Senior Analytical Scientist

Job Title: Analytical Scientist

Job Description

The Analytical Scientist leads unknown compound identification using advanced mass spectrometry techniques to support pharmaceutical, medical device, and extractables and leachables (E&L) studies. This role requires deep expertise in LC/MS, strong regulatory knowledge, and the ability to provide technical leadership in solving complex analytical challenges within a cGMP/GLP environment.

Responsibilities

• Lead unknown peak and compound identification using LC/MS, LC‑MS/MS, and high‑resolution mass spectrometry (LC‑HRMS) in support of pharmaceutical, medical device, and E&L studies.
• Operate, maintain, and troubleshoot LC/MS and high‑resolution MS systems to ensure high data quality and instrument reliability.
• Interpret complex mass spectrometry data, including fragmentation patterns, to support structure elucidation and structure confirmation.
• Investigate and resolve analytical challenges related to methods, instrumentation, and complex sample matrices, proposing and implementing effective solutions.
• Prepare, review, and approve technical reports, study protocols, and regulatory documentation in alignment with relevant guidelines (including ISO‑18 and USP <1663>/<1664>).
• Collaborate closely with cross‑functional teams and Quality Assurance to communicate results, address study needs, and provide expert technical guidance.
• Mentor, train, and support junior scientists in mass spectrometry techniques, unknown identification strategies, and best practices in analytical chemistry.
• Stay current with emerging analytical technologies, mass spectrometry methodologies, and regulatory expectations, and drive continuous improvement in laboratory practices and workflows.

Essential Skills

• PhD in Analytical Chemistry or a closely related field.
• At least 5 years of industry experience in analytical chemistry or a related discipline.
• Strong expertise in LC/MS and high‑resolution mass spectrometry, including LC‑MS/MS and LC‑HRMS.
• Deep understanding of mass spectrometry principles, fragmentation behavior, and structure elucidation strategies.
• Solid organic chemistry with practical structure‑confirmation skills.
• Experience working in GLP, GMP, and ISO‑regulated laboratory environments.
• Proficiency with mass spectrometry software platforms, with experience in Sciex OS and Thermo/Chromeleon preferred.
• Strong problem‑solving skills with a proven ability to troubleshoot methods, instruments, and complex analytical issues.
• Clear and effective written and verbal communication skills for technical reporting and cross‑functional collaboration.
• Demonstrated ability to mentor and train junior scientists.

Additional Skills & Qualifications

• Experience with GC/MS as a complementary technique to LC/MS.
• analytical chemistry applied to pharmaceutical, biotech, or medical device studies.
• Familiarity with extractables and leachables (E&L) studies and related regulatory expectations.
• Ability to contribute to continuous improvement initiatives and implement new analytical technologies.
• Strong collaboration skills and a team‑oriented mindset in a multidisciplinary laboratory environment.

Work Environment

This is a fully onsite role, based in a laboratory environment operating under cGMP/GLP and ISO standards. The position requires working on site five days per week, Monday through Friday, during standard business hours of approximately 8:30 a.m. to 5:00 p.m. You will work with advanced LC/MS, LC‑MS/MS, and high‑resolution MS instrumentation, as well as associated chromatography and data analysis software platforms such as Sciex OS and Thermo/Chromeleon. The organization focuses on toxicology, biocompatibility, pharmacology, analytical chemistry, and microbiology testing to support clients in the pharmaceutical, biotech, and medical device sectors, offering a mission‑driven culture dedicated to improving public health through science.

Job Type & Location

This is a Contract to Hire position based out of Hercules, CA.

Pay and Benefits

The pay range for this position is $55.00 - $64.90/hr.

Eligibility requirements apply to some benefits and may depend on your job classification and length of employment. Benefits are subject to change and may be subject to specific elections, plan, or program terms. If eligible, the benefits available for this temporary role may include the following:

• Medical, dental & vision
• Critical Illness, Accident, and Hospital
• 401(k) Retirement Plan - Pre-tax and Roth post-tax contributions available
• Life Insurance (Voluntary Life & AD&D for the employee and dependents)
• Short and long-term disability
• Health Spending Account (HSA)
• Transportation benefits
• Employee Assistance Program
• Time Off/Leave (PTO, Vacation or Sick Leave)

Workplace Type

This is a fully onsite position in Hercules,CA.

Application Deadline

This position is anticipated to close on Apr 30, 2026.

Diversity, Equity & Inclusion

At Actalent, diversity and inclusion are a bridge towards the equity and success of our people. DE&I is embedded into our culture through:

• Hiring diverse talent
• Maintaining an inclusive environment through persistent self-reflection
• Building a culture of care, engagement, and recognition with clear outcomes
• Ensuring growth opportunities for our people

Actalent is an equal opportunity employer.

About Actalent

Actalent is a global leader in engineering and sciences services. For more than 40 years, we've helped visionary companies advance their goals. Headquartered in the United States, our teams span 150 offices across North America, EMEA, and APAC-with four delivery centers in India led by 1,000+ extraordinary employees who connect their passion with purpose every day.

Our Bangalore, Hyderabad, Pune, and Chennai delivery centers are hubs of engineering expertise, with core capabilities in mechanical and electrical engineering, systems and software, and manufacturing engineering. Our teams deliver work across multiple industries including transportation, consumer and industrial products, and life sciences. We serve more than 4,500 clients, including many Fortune 500 brands. Learn more about how we can work together at actalentservices.com.