Senior Associate - Analytical Chemist

Sr. Associate - Analytical Chemist

Location: Cambridge, MA

Onsite Flexibility: Onsite

Contract Details

• Position Type: Contract
• Contract Duration: 6 months
• Pay Rate: $25.00 $28.00 / Hour (USD)
• Work Authorization: Applicants must be authorized to work for ANY employer in the U.S. We are unable to sponsor or take over sponsorship of an employment Visa at this time.

Job Summary

The client is currently seeking an Analytical Chemist in their Pivotal Attribute Sciences Department in Cambridge, MA. This team plays a crucial role in pivotal phase analytical support, including product development support, testing of drug substances and drug products. The role will work closely with a team of analysts and scientists responsible for the technical aspects of developing analytical tools to gain an understanding of key quality attributes in product and process for late-phase synthetic small molecule, synthetic peptide, and/or antibody peptide conjugates. The scientist will integrate and optimally utilize the platform and in-depth product attribute knowledge to advance the client's products and ensure success through pivotal clinical phases to marketing authorization application. In this vital role, you will integrate and optimally utilize platform and in-depth product attribute knowledge to advance the client's products and ensure success through pivotal clinical phases to marketing authorization application.

This individual will support chemists by analyzing samples using various chromatographic techniques, optimizing analytical methods for accuracy and repeatability, and troubleshooting instrumentation as needed. The ideal candidate should demonstrate strong problem-solving skills, be adept at overcoming complex analytical challenges, and take a proactive approach to supporting and improving laboratory operations.

Key Responsibilities

• Prepare samples and perform routine analyses utilizing liquid chromatography.
• Participate in the development and optimization of HPLC methods.

Required Skills

• Use Waters Empower system (or other LC platform) to perform liquid chromatography analysis; experience in large molecule analysis is a plus.
• Experience with operation, maintenance, and troubleshooting of chromatographic and spectroscopic laboratory equipment.
• Conduct liquid chromatography analysis using Empower or similar LC platforms; experience with large molecule analysis is preferred.
• Develop, optimize, and validate analytical methods for synthetic peptide release testing and characterization.
• Collaborate closely with drug substance and drug product process development colleagues to achieve project objectives.
• Hands-on experience with chromatographic techniques such as Reversed-Phase Liquid Chromatography (RPLC).
• Proficiency with the Waters Empower Chromatography Data System (CDS) for data acquisition, processing, and management.

Preferred Skills

• 2 years of experience in the pharmaceutical or biotech industry, focusing on process and product development and analytical method development for drug substances and products.
• Experience in analytical method development, characterization, and analytical control strategy, especially having mass spectrometry (MS) experience.
• Experience in fundamental programming skills (such as Python, MATLAB, etc.).
• Familiarity with USP monographs and chapters, and ICH/FDA guidance documents related to analytical method transfer and validation, impurities, mutagenic impurities, etc.
• Understanding of GLP and GMP requirements and their application in a phase-appropriate manner.
• Experience in technical transfer for non-GMP and GMP production and testing to external contract organizations, able to manage deliverables against timelines.
• Excellent communication skills and ability to provide cross-functional leadership and guidance to CMC and non-clinical teams, e.g., informing and defending the Quality Target Product Profile.
• Ability to work effectively in cross-functional teams and across various geographic locations in different time zones.
• Excellent technical writing skills with attention to detail in authoring methods, specifications, technical reports, and regulatory filing documents.
• Experience in working with large molecules such as peptides and synthetic small molecules.

Education Requirements

• Master's degree OR Bachelor's degree and 2 years of experience OR Associate's degree and 4 years of experience OR High school diploma/GED and 6 years of experience.
• The ideal candidate will hold a Master's or higher degree in Analytical Chemistry, Organic Chemistry, Physical Chemistry, Pharmaceutical Sciences, Life Sciences, or Engineering, with at least 2 years of experience in the pharmaceutical industry.

Benefits

• Medical, Vision, and Dental Insurance Plans
• 401k Retirement Fund

Important Notes

• 100% Onsite at the Cambridge site. Local candidates only this position is not open to relocation candidates due to urgent hiring needs.
• Interview process: Resumes will be collected for 1 2 weeks; the hiring manager will send 3 5 candidates to HR for phone screening (1 week), followed by video interviews with 2 3 candidates before a final decision is made (1 2 weeks).

About GTT

GTT is a minority-owned staffing firm and a subsidiary of Chenega Corporation, a Native American-owned company in Alaska. We highly value diverse and inclusive workplaces and support Fortune 500 organizations across banking, financial services, technology, life sciences, biotech, utilities, and retail sectors throughout the U.S. and Canada.

Job Number: 26-07714

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