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Senior Bioinformatics Scientist

Boston Children's Hospital

Boston, MA

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JOB DETAILS
SKILLS
Analysis Skills, Best Practices, Bioinformatics, Biomedical Research, Cloud Computing, Cloud Storage, Communication Skills, Computer Systems, Data Migration, Documentation, Documentation Standards, Genomics, Git, Hardware Upgrades, Hospital, Human Diseases, Informatics, Knowledge Management Systems, Leadership, Mathematics, Microscopy, Next Generation Sequencing (NGS), Open Source, Pediatrics, Presentation/Verbal Skills, Problem Solving Skills, Programming Languages, Project/Program Coordination, Proteomics, Publications, Python Programming/Scripting Language, R Programming Language, Research Skills, SQL (Structured Query Language), Scientific Publications, Scientific Research, Set Goals, Source Code/Configuration Management (SCM), Staff Training, Standard Operating Procedures (SOP), Systems Administration/Management, Systems Maintenance, Team Player, Technical Writing, Time Management, Translational Research, Virtual Machine (VM), Virtualization, Web Programming
LOCATION
Boston, MA
POSTED
30+ days ago
Position Summary 
Research Computing supports basic, translational, and clinical research by providing researchers with access to digital tools and technologies. Our computing environment consists of high-performance computing clusters, virtual machines, PetaByte-scale high-performance storage and cloud platforms. We work with BCH scientists to develop solutions in support of cutting-edge research ranging from lattice light-sheet microscopy to CryoEM, genomics, and informatics.

The role will work with PhD-level bioinformatics scientists and researchers who have single-cell RNA-seq, bulk RNA-seq, proteomics and image data to investigate mouse and human diseases as well as with other pediatric scientists at BCH. The primary responsibilities will be building pipelines and web-based tools for the analysis, integration and sharing of these data. You will analyze, integrate different types of next-generation sequencing data and interpret the results and will have the opportunity to publish high-profile papers with prominent authorship depending on the intellectual contribution. The ideal candidate should have enthusiasm for developing collaborative relationships and a desire to foster the use of bioinformatics data in research studies.

Key Responsibilities: 
  • Providing computational support by applying a wide range of bioinformatics tools and technologies; completing assignments independently and on time; consistently adhering to and promoting standard operating procedures and best practices; maintaining and upgrading research computing tools and technologies, migrating data, documenting changes, and adjusting internal processes.
  • Routinely leading or participating in complex Research Computing projects with other members from the BCH research community; setting goals and objectives for projects and demonstrating achievement of those goals and objectives; coordinating work activities with other stakeholders; contributing to the resulting presentations and/or publications.
  • Training staff and researchers; effectively tailoring presentations; developing, implementing and maintaining knowledge management systems.
  • Communicating scientific findings clearly through presentations, email, memos, and scientific publications; presenting progress at project and departmental meetings; facilitating productive discussions and problem-solving.
Minimum Qualifications
Education: 
  • Bachelor's degree in science, technology, engineering or mathematics. Preference for candidates with a Ph.D. in Bioinformatics, Computational Biology or related. 
Experience:
  • A minimum of one year of position-specific experience. 
  • Extensive knowledge of the use of bioinformatics computations in high-performance computing environments and web development, including open-source bioinformatics software and pipelines to support diverse bioinformatics analyses such as single-cell RNA-seq, bulk RNA-seq, proteomics, etc.
  • Extensive knowledge of technologies used in support of biomedical research, such as programming languages (R and Python), databases (SQL), version control (Git), scientific workflow tools and high-performance computing clusters. Cloud computing tools would be a bonus.
  • Ability to resolve a wide range of complex Research Computing assignments in support of biomedical research. Ability to routinely lead complex projects and coordinate project teams; readiness to seek advice and guidance when needed and to operate effectively in collaboration with scientists and clinicians; ability to follow, improve and create technical documentation and standard operating procedures.
  • Strong publication record. Ability to effectively convey messages through written communication that are tailored to target audience; meeting discussions and one-on-one verbal communications are clear and effective; ability to conduct effective meetings, to present in departmental and hospital forums, and to develop training instructions and manuals.

About the Company

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Boston Children's Hospital

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