Biotech and Pharmaceutical, Case Report Form (CRF), Clinical Monitoring, Clinical Practices/Protocols, Clinical Research, Clinical Trial, Communication Skills, Cross-Functional, Customer Relations, GCP (Good Clinical Practices), ICH Regulations, Legal, Oncology, Organizational Skills, Phase III Clinical Trials, Problem Solving Skills, Quality Management, Research Protocols, Standard Operating Procedures (SOP), Willing to Travel, Work From Home
Piper Companies is seeking a Senior Clinical Research Associate (Oncology) to join a clinical research organization supporting biotech-sponsored Phase II-III Oncology studies. The Senior Clinical Research Associate will play a critical role in trial execution, site management, and monitoring activities while serving as a key partner to investigative sites and study sponsors. This position is remote with regional travel throughout assigned territories. Candidates must reside within one hour of a major airport. Must be authorized to work in the United States.
Responsibilities for the Senior Clinical Research Associate:
- Independently monitor Phase II-III Oncology clinical trials in accordance with ICH-GCP guidelines, study protocols, and SOPs
- Conduct site initiation, routine monitoring, and close-out visits, averaging approximately 8 onsite monitoring days per month
- Perform source data review (SDR), source data verification (SDV), and case report form (CRF) review to ensure accurate, high-quality, inspection-ready data
- Partner closely with investigative sites to support patient enrollment, protocol adherence, and issue resolution
- Identify site-level risks and escalate concerns appropriately to maintain study quality and timelines
- Collaborate directly with biotech sponsors and cross-functional study teams to ensure successful clinical trial execution
- Manage multiple sites, study activities, and priorities while working independently with minimal oversight
Requirements for the Senior Clinical Research Associate:
- Experience as a Senior Clinical Research Associate supporting Oncology clinical trials
- Strong background in independent site monitoring and clinical trial oversight
- Experience supporting Phase II and/or Phase III studies
- Comprehensive knowledge of ICH-GCP guidelines and clinical research regulations
- Ability to work directly with biotech sponsors in a client-facing environment
- Strong organizational, communication, and problem-solving skills
- Ability to manage multiple sites and competing priorities with minimal supervision
- Must reside within one hour of a major airport and be able to travel regionally
Must be authorized to work in the United States
Compensation for the Senior Clinical Research Associate:
- Competitive salary plus bonus, depending on experience
- Full benefits including medical, dental, vision, 401(k), PTO, and sick leave as required by law
- Remote work environment with regional travel requirements
This job opens for applications on July 10th, 2026. Applications for this job will be accepted for at least 30 days from the posting date.