Senior Director, Migraine Lifecycle & Strategy Lead

In Global Commercial Strategy (GCS), we translate the science of R&D into value for patients and Pfizer - from early development through launch, growth, and lifecycle. Migraine is a chronic, often debilitating disease that can significantly impact a person's ability to work, care for family, and fully participate in everyday life. As the migraine treatment landscape evolves from simply managing acute symptoms to preventing disease burden, the Migraine franchise is uniquely positioned to help more patients achieve meaningful relief through innovative oral CGRP therapies. The business is projected to have strong growth over the next few years reaching global peak revenues of over $3B. 

What You Will Achieve

The Senior Director, Migraine Lifecycle & Strategy Lead is a senior individual contributor role in the Global Commercial Strategy organization, reporting to the Global Migraine Commercial Team Lead. This role will lead through influence and cross-functional matrixed leadership to shape strategic recommendations and support critical commercial decisions and objectives.

The colleague will own lifecycle strategic planning across all current and future indications, lead the franchise's competitive intelligence strategy & response, develop the long-range forecast assumptions and partner closely with Medical, Clinical, H&V, and Commercial colleagues on evidence generation priorities. The role will also lead the development of the market shaping strategy, working in close partnership with Medical, Policy and Communications colleagues ensuring external and internal narratives are aligned with franchise priorities.

This role requires an experienced commercial strategist with strong analytical rigor, sound judgment under ambiguity, and the ability to translate competitive, scientific, and market signals into clear implications and mitigation plans.  The Sr. Director will partner closely with the Global XFT as well as US and ICO/EM colleagues to integrate perspectives and drive decision-making. 

Responsibilities

Lifecycle Strategic Planning:

• Lead lifecycle strategic planning and assessments across current and future Migraine indications integrating evidence generation, regulatory, and market dynamics into a coherent long-range plan.

• Translate lifecycle priorities into clear recommendations and decision materials for franchise leadership and governance forums.

• Lead insight generation, develop launch strategies and long-range forecasts for all lifecycle launches, including QD, MM, FTC and Chronic

Competitive Intelligence Leadership:

• Serve as CI Lead for the Migraine Franchise, owning monitoring and generation of competitive insights and their strategic implications.
• Drive competitive scenario planning and war-game differentiation strategies across the full GTM model to proactively address competitor moves, pipeline developments, new data/publications, and market shifts.
• Lead the Rapid Response Team, ensuring the franchise can react quickly and coherently to competitive events.

Evidence Generation:

• Partner with Medical Affairs, H&V and Clinical Development to shape evidence generation priorities that support lifecycle and competitive positioning goals.
• Have a thorough understanding of our data and identify data gaps and opportunities in close partnership with Regional/US commercial teams to improve value proposition and recommendations

Long-Range Forecasting & OP Guidance:

• Own OP long-range forecast (LRF) assumptions and provide guidance to regional teams/markets and cross-functional partners.
• Ensure forecast assumptions reflect the latest competitive intelligence and lifecycle plan updates.

Market Shaping:

• Lead market shaping strategy and plan development for the Migraine Franchise, aligning closely with commercial, medical, policy and communications colleagues.
• Liaise with the Communications team on internal and external communications.

Global Performance Support:

• Support global performance reviews and reporting for the Migraine Franchise, as needed.
• Demonstrate an absolute commitment to Pfizer values and adherence to all applicable compliance rules and regulations.

Qualifications

Must Have

• Applicant must have a bachelor's degree with at least 12 years of experience; OR a master's degree with at least 10 years of experience; OR a PhD with 7+ years of experience.
• Experience in pharmaceutical, biotechnology, or life sciences commercial roles, with direct exposure to lifecycle management, competitive intelligence, or franchise strategy.
• Demonstrated experience leading complex cross-functional initiatives and influencing senior stakeholders in matrixed environments without direct authority.
• Strong analytical and strategic skills, with the ability to synthesize competitive, scientific, and market signals into clear implications and competitive response plans.
• Experience with long-range forecasting, evidence generation planning, or OP-cycle guidance.
• Strong communication, executive presence, and stakeholder management skills.
• Strong work ethic and proven track record of delivering high quality within timelines.

Preferred

• Experience in Migraine, Neurology, or other complex specialty therapeutic areas.
• Experience leading a Rapid Response or competitive response capability.
• Experience partnering with Medical, H&V, Policy and/or Communications teams on market shaping strategy.
• Comfort working in an AI-enabled or AI-augmented environment; experience using AI tools to support strategy, synthesis, or analysis is a plus.
• Ability to thrive in ambiguity, operate with an enterprise mindset, and adapt to evolving franchise priorities.
• Diverse leadership experience including in-market and above country/regional/global scope

 
Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.

NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS

Availability to travel internationally up to 30% of the time

Additional Job Information:

Last Date to Apply: August 14, 2026
Work Location Assignment: Hybrid

The annual base salary for this position ranges from $214,900.00 to $358,100.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 22.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States. This role is posted in multiple locations. If you are applying for the role in an secondary job posting location where pay transparency regulations apply, your Talent Advisor will share the local pay information with you during the first interview.

Relocation assistance may be available based on business needs and/or eligibility.

Candidates must be authorized to be employed in the U.S. by any employer.

U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.

To learn more about acceptable and prohibited uses of AI during the recruitment process, please review our candidate AI-use guidelines available on Pfizer Careers.

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