Senior Director, Tilrekimig Launch Operations

Global Commercial Strategy (GCS): Senior Director, Tilrekimig Launch Operations

Why Patients Need You

Everything we do, every day, is driven by an unwavering commitment to the patients, healthcare providers, and customers who depend on us. In Global Commercial Strategy (GCS), we translate science of R&D into value for patients and Pfizer — from early development through launch, growth, and LOE lifecycle. GCS serves as the strategic engine and commercial voice across the asset lifecycle — shaping asset positioning and evidence generation, leading global launches, and driving sustained access and brand performance through market and payer insights, broad access, & commercial rigor. We take pride in shaping how innovative medicines reach the people who need them most, and ensuring they are accessible, understood, and valued across every market. Our success is anchored in the following Pfizer Blueprint values: Science, Technology, Transformation and Colleagues. Whether you are defining strategy, managing brands at different lifecycle, or building the capabilities that power our commercial engine, your work directly shapes patient outcomes and the long-term success of Pfizer's portfolio.

Role Summary:

The Senior Director, Tilrekimig is a senior individual contributor role within the Inflammation & Immunology (I&I) / Rare Disease business, part of the Global Commercial Strategy organization, reporting to the Global Commercial Lead (GCL), CIB/TIL. This role has no direct reports and will lead through senior matrix leadership. As the Launch Operations Lead for tilrekimig, the role is responsible for enabling flawless operational execution of the global launch plan — driving cross-functional integration, timelines, governance, and launch readiness across all three indications. The mandate spans both strategic and operational deliverables for a blockbuster launch of high complexity, but is more operational than the Global Launch Lead role, ensuring the GCL and leadership teams have the structure, tools, insights, and processes to accelerate tilrekimig’s path to launch.

The broader I&I and Rare Disease portfolio represents significant strategic value to realizing Pfizer's vision to achieve leadership via breakthroughs in prioritized diseases and biological axes, with the goal of generating highly differentiated, multi-indication mega-blockbusters. Today, the portfolio delivers more than $10B globally, with 22 ongoing clinical studies underway to significantly expand the product portfolio over the next several years. This role will contribute to that ambition by helping shape the commercial strategy and launch foundation for a high-priority I&I pipeline asset with potential to address significant unmet need across Type 2 inflammatory diseases.

Tilrekimig (PF-07275315) is an investigational trispecific antibody with potential to be a first-in-class, once-monthly treatment option targeting interleukin-4 (IL-4), interleukin-13 (IL-13), and thymic stromal lymphopoietin (TSLP) for multiple chronic Type 2 inflammatory conditions, including atopic dermatitis, asthma, and chronic obstructive pulmonary disease (COPD). Following positive Phase 2 results in moderate to severe atopic dermatitis and ongoing development across additional Type 2 inflammatory diseases, this colleague will help translate scientific and clinical potential into a launch-ready operational foundation, integrated cross-functional execution, and a clear, well-governed path to launch for patients, healthcare providers, payers, and markets.

The Senior Director will partner closely with the GCL (CIB/TIL), R&D, Medical Affairs, Global Access Strategy & Pricing (GASP), Business Analytics & Insights, Competitive Intelligence, Regulatory, Legal, Compliance, CMO, and US and International Commercial teams to drive cross-functional integration, manage launch timelines and governance, anticipate operational risks, and ensure launch readiness is grounded in patient need, scientific differentiation, access considerations, competitive dynamics, and enterprise value.

Responsibilities:

Global Launch Strategy and Enterprise Launch Program Management (DLPP):

· Deliver the Global Integrated Launch Strategy, including evidence positioning, indication sequencing, indication-specific value propositions, and portfolio integration.

· Lead end-to-end launch operations, including timelines, critical path management, risk mitigation plans, and scenario-planning frameworks.

· Maintain the cross-indication Launch Roadmap (DLPP) covering asset, evidence, regulatory, supply, medical, commercial, and regional readiness.

·  Integrate atopic dermatitis learnings and support new Respiratory capabilities (asthma and COPD) across the organization.

· Champion transformative processes and AI aligned to Pfizer Blueprint 2030 to meet all ELA Launch Stage Gates.

Launch Governance and Decision Support:

· Run governance forums, including the Global Launch Team (GLT), sub-teams, readiness reviews, and the Launch Excellence Council.

· Deliver the ELA process for tilrekimig and ensure all functions and senior leadership adhere to it.

· Lead creation and evolution of the Launch Playbook, including OGSM, the Market Development Plan, and Brand Positioning.

· Deliver a fully costed resourcing and launch tactical plan to ensure a successful tilrekimig launch.

· Create senior-leadership readouts, including OGSM materials, senior leader updates, and asset milestone reviews.

Operational Integration Across Functions:

· Ensure alignment between core Global functions so that launch stage gates are achieved:

· Commercial; Medical (Integrated Evidence Plan); HEOR (Integrated Value & Access Strategy); Regulatory (North Star); and Supply / Manufacturing.

· Anticipate operational risks and realize acceleration opportunities, championing transformative processes and AI aligned to Pfizer Blueprint 2030.

Launch KPI Monitoring and Performance Management:

· Build global launch dashboards covering KPIs, milestones, and risk indicators.

· Own readiness frameworks, including Enterprise Launch Excellence checklists and functional readiness matrices.

Regional and Country Enablement (in close collaboration with US and ICO launch teams):

· Ensure launch readiness across regions and priority markets through global frameworks, capability building, and market engagement tools.

· Lead global-to-regional alignment, including LRF forecasts, launch excellence KPIs, and readiness reviews.

Budget, Resourcing and Vendor Management:

· Oversee global launch budget tracking, resourcing models, and vendor / program partner management.

Basic Qualifications:

· Bachelor's degree required; MBA or advanced degree preferred.

· 12+ years of pharmaceutical, biotechnology, or life sciences experience in marketing, strategy, commercial development, launch planning, brand management, or related commercial roles.

· Strong strategic marketing experience, including development of brand strategy, positioning, core messaging, launch readiness deliverables, and commercial tactical architecture.

· Demonstrated ability to translate scientific and clinical data, customer insights, market dynamics, access considerations, and competitive intelligence into meaningful commercial strategies and recommendations.

· Experience leading complex cross-functional initiatives and influencing senior stakeholders without direct authority in a global or matrixed environment.

· Strong analytical and strategic skills, including the ability to identify and prioritize strategic challenges, balance short-term needs with long-term vision, and make recommendations with incomplete information.

· Excellent verbal and written communication skills for senior leadership, cross-functional partners, and a wide variety of audiences.

· Demonstrated commitment to Pfizer values and adherence to all applicable compliance rules and regulations.

Preferred Qualifications:

· Advanced degree in business, life sciences, medicine, pharmacy, public health, or related field preferred.

· Experience in Inflammation & Immunology, dermatology, respiratory, Type 2 inflammatory disease, specialty care, biologics, or other complex therapeutic areas preferred.

· Global marketing, above-country, US, International, or launch experience strongly preferred.

· Experience developing HCP strategy, Medical Education strategy, congress strategy, core content packages, and agency-led commercial deliverables.

· Understanding of market access dynamics, evidence generation, payer considerations, value demonstration, and launch sequencing.

· Ability to thrive in ambiguity, operate with urgency, and navigate complex scientific, clinical, commercial, and organizational considerations.

· Comfort working in an AI-enabled or AI-augmented environment; experience using AI tools to support strategy, synthesis, content development, or analysis is a plus.

· Discretion, sound judgment, and trustworthiness in handling confidential or sensitive organizational matters.

 Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.

NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS

Global travel required, up to 25%

Last Day to Apply: July 1, 2026
Work Location Assignment: Hybrid

The annual base salary for this position ranges from $214,900.00 to $358,100.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 22.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States. This role is posted in multiple locations. If you are applying for the role in an secondary job posting location where pay transparency regulations apply, your Talent Advisor will share the local pay information with you during the first interview.

Relocation assistance may be available based on business needs and/or eligibility.

Candidates must be authorized to be employed in the U.S. by any employer.

U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.

To learn more about acceptable and prohibited uses of AI during the recruitment process, please review our candidate AI-use guidelines available on Pfizer Careers.

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