Lead preventive/predictive/corrective maintenance across AHUs, chillers, boilers, heat exchangers, VAVs, exhaust, dehumidifiers, and split systems-owning temperature, humidity, airflow, and pressurization in GMP spaces.
Ensure cleanroom compliance with ISO 14644: HEPA integrity, airflow patterns, recovery times, and differential pressures; support aseptic areas and gowning zones.
Optimize and troubleshoot BMS/EMS/SCADA (Siemens, Allen-Bradley, Johnson Controls): tune PID loops, rationalize alarms, adjust sequences of operation, and document via change control.
Coordinate calibration (temperature, RH, pressure, flow) and support IQ/OQ/PQ with solid validation documentation.
Drive investigations and CAPA using RCA methods (5-Why, Fishbone) and maintain impeccable cGMP/GDP records and SOPs.
Champion audit readiness (FDA/EU GMP) and keep systems in a validated state.
Improve energy and performance: VFDs, heat recovery, demand-based ventilation, and smart control strategies.
Plan and execute outages/turnarounds/capital projects with contractors, materials, and risk assessments.
Lead safety culture (LOTO, confined space, hot work, arc-flash; EPA 608 refrigerants) and mentor junior techs.
Manage spares and CMMS workflows; partner closely with Quality, Manufacturing, Engineering, Validation, and Operations.
Impact that matters: Your work directly supports compliant manufacturing and product quality.
Variety and ownership: Complex systems, cross-functional collaboration, and continuous improvement.
Growth and mentorship: Be the SME and coach for a high-performing team.
Minimum Requirements:
High school diploma/GED
6-10+ years in HVAC maintenance, including 3-5 years in pharma/biotech or regulated GMP environments
Diagnostics: Advanced troubleshooting, basics of vibration analysis and thermography; instrumentation (anemometers, micromanometers, particle counters, data loggers).
Soft skills: Clear communication, teamwork, stakeholder management, decisive under time pressure, meticulous documentation.
Physical: Lift 50 lbs, ladders/heights/mechanical spaces, PPE for labs/cleanrooms, after-hours/on-call rotation.
Desired:
Technical diploma/apprenticeship in HVAC/Mechanical/Building Services;
Bachelor's in Mechanical/Building is a plus.
Certifications: Safety training preferred; manufacturer training on chillers/controls and GxP/cleanroom courses are a plus.
Interested? Apply to join our Technical Operations team in Santa Monica or Tarzana and help us keep mission-critical environments running flawlessly.
The annual base pay (or hourly rate of compensation) for this position ranges from $71,749.60 - 107,624.40 . Our positions offer eligibility for various incentives-an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.
Date Posted
04-Aug-2026
Closing Date
21-Aug-2026
Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.
Numbers & Facts
Location
Santa Monica, CA
Industry
Biotechnology/Pharmaceuticals
Salary
$71,749.60–$107,624.40 Per Year
Company Size
10,000 employees or more
Website
https://www.astrazeneca.com/
About Company
AstraZeneca is one of the world’s most exciting bio-pharmaceutical companies. From scientists to sales, lab techs to legal, we’re on a mission to turn ideas into life-changing medicines that improve patients’ lives and benefit society. We need great people who share our passion for science and have the drive and determination to meet the unmet needs of patients around the world.
Skills
Allen-Bradleyunmatched
Analysis Skillsunmatched
Asepsisunmatched
Biotech and Pharmaceuticalunmatched
Calibrationunmatched
Capital Projectunmatched
Change Controlunmatched
Cleanroomunmatched
Coachingunmatched
Communication Skillsunmatched
Computerized Maintenance Management System (CMMS)unmatched
Continuous Improvementunmatched
Corrective and Preventative Action (CAPA) Systemsunmatched
Cross-Functionalunmatched
Current Good Manufacturing Practice (cGMP)unmatched
Data Qualityunmatched
Documentationunmatched
Environmental Protection Agency (EPA)unmatched
FDA (Food and Drug Administration)unmatched
GMP (Good Manufacturing Practices)unmatched
GxPunmatched
HVACunmatched
Heat Exchangerunmatched
High School Diplomaunmatched
ISO (International Organization for Standardization)unmatched
Identify Issuesunmatched
Instrumentationunmatched
Lift/Move 50 Poundsunmatched
Maintain Complianceunmatched
Maintenance - HVACunmatched
Maintenance Servicesunmatched
Manufacturingunmatched
Materials Analysisunmatched
Mentoringunmatched
On Callunmatched
Performance Managementunmatched
Power Outagesunmatched
Process Validationunmatched
Risk Analysisunmatched
Safety Trainingunmatched
Standard Operating Procedures (SOP)unmatched
Supervisory Control and Data Acquisition (SCADA)unmatched
System Validationunmatched
Team Playerunmatched
Technical Operationsunmatched
Validation Documentationunmatched
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