Job Description
Pay: $45-50/Hour
Duration:18 months
Location: Onsite – Emeryville, CA
About the Role
Key Responsibilities:
Qualifications:
Duration:18 months
Location: Onsite – Emeryville, CA
About the Role
- We are seeking a highly motivated and collaborative Senior Scientist to support the development and execution of in vitro ADME assays for the evaluation and optimization of potential therapeutic candidates. This onsite role, based in Emeryville, CA, will contribute to drug discovery programs by generating high quality data to inform compound progression and candidate selection.
- The ideal candidate will have hands-on experience conducting in vitro ADME assays in a biopharmaceutical, pharmaceutical, or contract research organization setting, with strong technical expertise in LCMS/MS, enzyme kinetics, cell-based assays, and data interpretation.
Key Responsibilities:
- Design, develop, and execute in vitro ADME assays to support drug discovery and candidate optimization.
- Conduct ADME screening studies, including but not limited to microsomal stability, hepatocyte stability, permeability, plasma protein binding, and related metabolism assays.
- Generate, analyze, interpret, and report high quality data to support project decisions and compound progression.
- Collaborate closely with DMPK, biology, chemistry, and project team members to ensure timely delivery of decision enabling data.
- Design and troubleshoot in vitro experiments to address project specific questions related to compound metabolism, stability, permeability, and protein binding.
- Contribute to LCMS/MS bioanalytical method development, sample analysis, assay optimization, and troubleshooting.
- Apply enzyme kinetic and quantitative bioanalytical principles to support assay design and data interpretation.
- Prepare experimental protocols, study summaries, technical reports, and presentations for internal stakeholders and project teams.
- Maintain accurate documentation in electronic laboratory notebooks and ensure adherence to internal quality and safety standards.
- Support implementation and use of laboratory automation platforms, as applicable.
Qualifications:
- BS or MS in chemistry, biochemistry, pharmacology, pharmaceutical sciences, biology, or a related scientific discipline.
- Minimum of 2 years of relevant hands-on in vitro ADME experience in a biopharmaceutical, pharmaceutical, or contract research organization environment.
- Strong understanding of DMPK and ADME principles, including assay design, data analysis, and interpretation.
- Demonstrated experience designing and executing automated in vitro assays to evaluate and optimize ADME properties of drug candidates.
- Handson experience with LCMS/MS based sample analysis; experience with Sciex instruments is preferred.
- Proficiency with data analysis and visualization tools such as Microsoft Excel, GraphPad Prism, Analyst, or similar software.
- Experience using electronic laboratory notebooks.
- Experience with laboratory automation platforms such as Hamilton, Tecan, or similar systems is preferred.
Numbers & Facts
| Location | Emeryville, CA |
| Industry | Staffing/Employment Agencies |
| Salary | $45–$50 Per Hour |
| Company Size | 500 to 999 employees |
| Website | https://www.thefountaingroup.com/ |
About Company
The Fountain Group provides Contingent Labor, Statement-of-Work, and Contingent-to-Permanent resources to clients with an internal/external Contingent Labor Managed Service Program or Clients without a program. The Fountain Group is committed to the belief that we all share in the responsibility to conduct our businesses in a socially and environmentally responsible manner. We base this on the premise that a company is much more than the products it offers. The effect a company has on the environment, the people and the communities it serves reflects the company’s dedication to being not only a good business, but to being a good corporate citizen. The Fountain Group believes the key to servicing a client is to identify the client demand precisely. Therefore, The Fountain Group focused its efforts on building and developing a process, which can identify an exact match for our client’s needs. Our process utilizes modern technology combined with 30+ years of Talent Acquisition experience to deliver Precision resources. Financial strength is prominent among The Fountain Group’s corporate values. The future of our business will be built on the innovation, compassion, outstanding services and technology, but a solid financial foundation is required to carry us forward to meet our business goal and support our long term vision.
Skills
- Analysis Skillsunmatched
- Assaysunmatched
- Biochemistryunmatched
- Biologyunmatched
- Biotech and Pharmaceuticalunmatched
- Chemistryunmatched
- Contract Research Organization (CRO)unmatched
- Data Analysisunmatched
- Data Qualityunmatched
- Data Visualization Toolsunmatched
- Documentationunmatched
- Drug Discoveryunmatched
- Drug-Screening Assaysunmatched
- Identify Issuesunmatched
- Laboratoryunmatched
- Laboratory Automationunmatched
- Laboratory Notebookunmatched
- Learning Content Management Systems (LCMS)unmatched
- Maintain Complianceunmatched
- Microsoft Excelunmatched
- Pharmacologyunmatched
- Plasmaunmatched
- Prismunmatched
- Safety Standardsunmatched
- Team Playerunmatched
- Technical Presentationunmatched
- Time Managementunmatched
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