Senior Laboratory Operations Associate

Prime Medicine Inc

Watertown, MA

JOB DETAILS
SKILLS
Administrative Management, Animal Research, Asset Management, Biology, Biotech and Pharmaceutical, Building Codes, Chemistry, Cleanroom, Communication Skills, Computerized Maintenance Management System (CMMS), Cross-Functional, Detail Oriented, Digital Asset Management, Documentation, Environmental Monitoring, Environmental Protection Agency (EPA), Facilities Management, GMP (Good Manufacturing Practices), Hazardous Materials/Substances, High Throughput, ISO (International Organization for Standardization), Just in Time (JIT), Kanban, Laboratory, Laboratory Information Management System (LIMS), Laboratory Management, Laboratory Operations, Lift/Move 50 Pounds, Manufacturing, Multitasking, On Call, Organizational Skills, Presentation/Verbal Skills, Preventative Maintenance, Regulations, Research & Development (R&D), Resource Conservation and Recovery Act (RCRA), Supplier Relationship Management (SRM), Supply Chain Management, Systems Administration/Management, Systems Maintenance, Telephone Skills, Vendor/Supplier Management, Vendor/Supplier Relations, Vendor/Supplier Selection, Writing Skills, Zoology
LOCATION
Watertown, MA
POSTED
30+ days ago

Position Summary

We are seeking a highly motivated Senior Laboratory Operations Associate with 3-5 years of hands-on experience supporting high-throughput, high-hazard chemistry, vivarium, and GMP operations. This individual will play a critical role in ensuring the smooth operation of a dynamic laboratory environment. The ideal candidate has a deep understanding of management of high-volume high hazard chemicals, asset management, is adaptable, detail-oriented, and a strong cross-functional communicator with a passion for operational excellence.

Key Responsibilities

• Under the guidance of the Senior Laboratory Manager, manage day-to-day operations in high-volume chemistry, biology, animal, and GMP laboratories, including supply management, asset management, chemical inventory, and waste handling. • Oversee management and administration of laboratory instrument service agreements, remedial repair, scheduling preventative maintenance, and digital asset management system. • Manage relationship with select vendors and suppliers. • Oversee the receipt, organization, and distribution of reagents and consumables to support chemistry workflows including 55-gallon drums of virgin chemicals and waste. • Ensure appropriate segregation, labeling, storage, and disposal of high-hazard chemicals, including Class A, Class B, water reactive materials, organic acids, inorganic acids, bases, and acutely toxic chemicals. • Coordinate with chemists to prepare and dispose of solid-phase resins, solvents, and purification materials in compliance with EHS protocols. • Monitor and maintain process systems and chemicals in 780 CMR/International Building Code (IBC) §307 designated High-Hazard Group Occupancy (H3 room). • Collaborate with vivarium staff to support animal research workflows, including supply delivery, sanitization cycles, live animal deliveries, and carcass disposal in accordance with 105 CMR 480.000. • Support cross-functional workflows between R&D and GMP labs. • Ensure documentation, materials movement, and environmental monitoring align with GMP compliance expectations. • Other responsibilities as required.

Qualifications

Education & Experience

• 3-5 years of direct hands-on experience in laboratory operations within a biotechnology environment. • Experience supporting high-hazard chemistry, vivarium operations, GMP manufacturing, and BSL-2 biology labs.

Required Skills & Competencies

• Experience working in ISO 5, 7, and 8 cleanroom environments. • Experience with 'just-in-time' supply chain management, KANBAN, 5S/Lean. • Familiarity with lab and facility management systems (e.g., LIMS, CMMS, asset management). • Comfortable working in environments requiring strict compliance: H3 occupancy, BSL-2, vivarium, and GMP. • Strong organizational and multitasking skills with an ability to work independently. • Excellent communication skills, both verbal and written. • Familiarity with 527 CMR 1.00, RCRA, EPA, DOT, HAZWOPPER, and IATA regulations.

Physical Requirements

• Ability to be on-call to receive and respond to alarms within 1 hour. • Ability to lift 50lbs, stand for extended periods, and perform repetitive physical tasks. • Comfortable working with hazardous materials while wearing appropriate PPE including the Advantage 420 Respirator, Tyvek Full GMP Sterile Coverall, lab coat, and 'silvershield' gloves.

About the Company

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Prime Medicine Inc