Senior Manager, Clinical Supply Chain – Remote | Pharmaceutical & Clinical Trials

Job ID: 37504289

Sigma Systems is seeking an experienced Senior Manager, Clinical Supply Chain for a 6-month remote contract. This role is ideal for a senior clinical supply chain professional with strong experience in clinical trial supply management, pharmaceutical development, drug supply planning, packaging and labeling, inventory management, distribution, vendor management, and cross-functional project leadership.

The successful candidate will manage end-to-end clinical supply activities across multiple clinical programs and work closely with Clinical Operations, CMC, Regulatory Affairs, Quality Assurance, Project Management, external partners, and Contract Manufacturing Organizations (CMOs) to ensure investigational products are available when and where needed.

Position Details

• Job Title: Senior Manager, Clinical Supply Chain
• Job ID: 37504289
• Location: Remote
• Contract: 6 Months
• Work Arrangement: 100% Remote
• Industry: Pharmaceutical / Biotechnology / Life Sciences
• Level: Senior Manager

Key Responsibilities

• Lead end-to-end clinical supply chain activities for assigned clinical programs, including supply planning, packaging, labeling, distribution, returns, and destruction.
• Manage drug supply planning, inventory control, distribution, and logistics activities across multiple clinical programs.
• Develop and manage clinical supply forecasts, supply plans, demand projections, and project timelines in collaboration with Clinical Operations and CMC.
• Coordinate clinical supply from manufacturers through depots and ultimately to clinical sites.
• Monitor and manage Investigational Product (IP) inventory levels at depots and clinical sites.
• Ensure timely availability of clinical trial supplies to support study milestones and patient enrollment.
• Manage label and packaging schedules and ensure clinical supply activities remain aligned with study timelines.
• Design, review, and coordinate clinical supply label text to meet product requirements and applicable U.S. and international regulations.
• Ensure investigational product management complies with clinical protocols, cGMP, GCP, ICH, FDA, and applicable international and local regulations.
• Manage and resolve clinical supply and logistics issues, including:
  • Shipment delays
  • Temperature excursions
  • Import/export issues
  • Distribution challenges
  • Inventory shortages or discrepancies
  • Packaging and labeling issues
• Partner with internal Trade Compliance and Logistics teams to resolve shipping and import/export matters.
• Collaborate closely with Clinical Operations, CMC, Regulatory Affairs, Quality Assurance, PDM, and external partners to ensure clinical supply readiness.
• Provide clinical supply chain leadership and represent the function at clinical trial and project team meetings.
• Communicate supply plans, milestones, risks, and timelines to internal stakeholders, vendors, CMOs, and external partners.
• Manage clinical supply vendors, including contracts, purchase orders, invoices, budgets, and performance.
• Participate in clinical supply chain budget and forecast planning.
• Oversee vendor activities and ensure external partners meet agreed timelines, quality standards, and deliverables.
• Review scope and implement changes affecting clinical supply programs.
• Support issue resolution, change implementation, and continuous improvement initiatives.
• Build strong working relationships with internal teams and external clinical supply partners.
• Ensure clinical supplies remain aligned with clinical study design, enrollment requirements, and overall program timelines.

Required Qualifications

• Bachelor's degree (BS/BA) in Life Sciences, Business, Supply Chain, Pharmaceutical Sciences, or related field required.
• Master's degree preferred.
• Minimum 5–7 years of experience in the life sciences industry.
• Experience in one or more of the following areas:
  • Clinical Supply Management
  • Pharmaceutical Development
  • Project Management
  • Clinical Trial Coordination
  • Pharmaceutical Supply Chain
• Minimum 3+ years of direct Clinical Supplies Management experience.
• Strong understanding of clinical trial supply processes and requirements.
• Demonstrated experience managing clinical supplies across early- and late-phase clinical programs.
• Strong knowledge of drug supply planning, packaging, labeling, distribution, inventory management, and clinical logistics.
• Understanding of clinical study designs, including randomized, blinded, and open-label studies.
• Experience working with CMOs, clinical supply vendors, depots, and clinical sites.
• Strong knowledge of applicable cGMP, GCP, ICH, FDA, and international regulatory requirements.
• Strong project management, organizational, communication, and problem-solving skills.
• Ability to manage multiple clinical programs, priorities, vendors, and timelines simultaneously.
• Strong experience working cross-functionally with Clinical Operations, CMC, Regulatory Affairs, QA, and other stakeholders.
• Excellent written and verbal communication skills.

Technical Skills

• Microsoft Excel
• Microsoft PowerPoint
• Microsoft Project
• Clinical supply management systems
• Supply forecasting and inventory planning tools
• Vendor management systems

Preferred Qualifications

• APICS certification, such as:
  • CPIM
  • CLTD
  • CSCP
• Master's degree in Life Sciences, Business, Supply Chain, Pharmaceutical Sciences, or related discipline.
• Experience supporting both early-phase and late-phase clinical trials.
• Experience with international clinical supply distribution and import/export requirements.
• Experience managing temperature-controlled shipments and temperature excursions.
• Experience with clinical supply budgets, purchase orders, contracts, and vendor invoices.