Senior Research Associate In vivo Pharmacology

Senior Research Associate, In Vivo Pharmacology

About Astellas

Astellas is a global life sciences company committed to turning innovative science into VALUE for patients. We provide transformative therapies in disease areas that include oncology, ophthalmology, urology, immunology and women's health. Through our research and development programs, we are pioneering new healthcare solutions for diseases with high unmet medical need. Learn more at Astellas.com.

Are you driven to make a real difference in the lives of patients?

We're seeking passionate individuals who thrive in dynamic environments, embrace new ideas, and aren't afraid to take intelligent risks. People who act with unwavering integrity and are deeply committed to making a tangible impact.

Purpose & Scope

The In Vivo Senior Research Associate is responsible for executing preclinical in vivo studies and generating reliable pharmacology data to support research project decisions. This position provides specialized in vivo expertise that is essential for the successful evaluation and advancement of therapeutic candidates.

Role and Responsibilities

• Execute and support preclinical in vivo oncology and immunotherapy studies using mouse tumor models, including xenograft and syngeneic systems.
• Perform routine animal handling, restraint, health monitoring, and study-related procedures in compliance with approved protocols and animal welfare regulations
• Conduct in vivo procedures including intravenous (IV), intraperitoneal (IP), oral gavage, subcutaneous, and other administration routes as required.
• Perform surgical procedures and tumor implantation to establish and maintain in vivo cancer models.
• Randomize animals into study groups and monitor clinical observations, body weight, and study endpoints.
• Collect biological samples, including blood, tissues, and tumors, and ensure accurate documentation of all study activities in accordance with company SOPs and applicable regulations.
• Apply hands-on expertise in cell culture, ex vivo flow cytometry, and data analysis to support translational and pharmacology studies.
• Ensure full compliance with IACUC, institutional policies, and regulatory requirements governing animal care and use.
• Collaborate effectively with scientists and cross-functional research teams to support preclinical oncology and pharmacology programs.
• Contribute to the generation of high-quality, reliable scientific data that supports project decision-making and advancement of therapeutic candidates.