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Senior Research Investigator

University of Pennsylvania

Philadelphia, PA

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JOB DETAILS
SALARY
$80,891–$100,000 Per Year
SKILLS
Analysis Skills, Automation Systems, Biology, Biomedical Engineering, Biophysics, Closing Costs, Communication Skills, Computer Programming, Computer Science, Computer Systems, Conferences, Data Sets, Data Visualization, Documentation, Entertainment and Media, Grant Writing, Instrumentation, Leadership, Legal, Localization, MATLAB, Medicine, Mentoring, Microscopy, Mortgage, Music, Needs Assessment, News Reporting, Organizational Skills, People Management, Physics, Presentation/Verbal Skills, Publications, Python Programming/Scripting Language, Quantitative Analysis, Scholarship, Science Software, Seminars, Software Administration, Software Development, Statistics, Team Player, Technical Research, Test Plan/Schedule, Test Tools, Theater Production, Training/Teaching, University Library, Workflow Analysis, Writing Skills
LOCATION
Philadelphia, PA
POSTED
16 days ago


University Overview


The University of Pennsylvania, the largest private employer in Philadelphia, is a world-renowned leader in education, research, and innovation. This historic, Ivy League school consistently ranks among the top 10 universities in the annual U.S. News & World Report survey. Penn has 12 highly-regarded schools that provide opportunities for undergraduate, graduate and continuing education, all influenced by Penn’s distinctive interdisciplinary approach to scholarship and learning. As an employer Penn has been ranked nationally on many occasions with the most recent award from Forbes who named Penn one of America’s Best Large Employers in 2023.




Penn offers a unique working environment within the city of Philadelphia. The University is situated on a beautiful urban campus, with easy access to a range of educational, cultural, and recreational activities. With its historical significance and landmarks, lively cultural offerings, and wide variety of atmospheres, Philadelphia is the perfect place to call home for work and play.




The University offers a competitive benefits package that includes excellent healthcare and tuition benefits for employees and their families, generous retirement benefits, a wide variety of professional development opportunities, supportive work and family benefits, a wealth of health and wellness programs and resources, and much more.








Posted Job Title

Senior Research Investigator





Job Profile Title

Research Investigator, Senior





Job Description Summary

The Senior Research Investigator will design, develop, implement, and maintain computational analysis tools for advanced fluorescence microscopy and super-resolution microscopy data. The position will be jointly based between the Lakadamyali Lab and the ACME core at the Perelman School of Medicine at the University of Pennsylvania, with an approximately 50/50 effort split between both groups. The Senior Research Investigator will, under limited supervision of Dr. Melike Lakadamyali and Dr. Mustafa Mir, lead independent software development and quantitative image analysis projects that support both fundamental biological research and core facility users across Penn.





Job Description


Job Description:


The Senior Research Investigator will build, validate, document, and deploy robust, custom-tailored and user-friendly image analysis pipelines for the analysis of super-resolution microscopy data, including but not limited to single-molecule localization microscopy, single-particle tracking, spatial statistics, and multi-dimensional image analysis. The successful candidate will work closely with the Lakadamyali Lab, ACME core leadership, Penn investigators, trainees, and collaborators.


The position requires an independent scientist with expertise in computational image analysis, microscopy, software development, and quantitative data interpretation. The successful candidate should have a highly analytical mindset and be able to identify analysis needs, design appropriate computational approaches, implement and test software tools, support the biological interpretation of imaging data, and help disseminate methods through publications, grants, and documentation.




Duties and Responsibilities:



+ Design, build, validate, and maintain user-friendly software tools for the analysis of advanced fluorescence microscopy and super-resolution microscopy data for use by the Lakadamyali Lab, ACME core users, and collaborators.


+ Develop analysis workflows for single-molecule localization microscopy, single-particle tracking, co-localization, spatial statistics, morpholomics analysis, and clustering.


+ Perform quantitative analysis and interpretation of complex microscopy datasets generated from biological samples, including cells and tissues.


+ Support, mentor, and train ACME core users by providing guidance on image analysis strategies, quantitative workflows, data interpretation, reproducible microscopy analysis practices, and tutorial development.


+ Interface with wet-lab collaborators to translate biological needs into appropriate quantitative image analysis strategies.


+ Write, test, optimize, and maintain code using appropriate programming and image analysis environments, including but not limited to MATLAB, Python, Fiji/ImageJ, and related scientific computing tools.


+ Generate figures, graphs, quantitative summaries, method descriptions, and data visualizations for manuscripts, grant proposals, presentations, and core facility reports.


+ Present research findings and technical developments at lab meetings, core facility meetings, seminars, conferences, and collaborative meetings.


+ Other duties as assigned.







Qualifications



+ A Ph.D in computational biology, quantitative biology, biophysics, engineering, computer science, biomedical engineering, physics or a related field is required, as well as 5-7+ years of postdoctoral or equivalent research experience in microscopy, image analysis, computational biology, or scientific software development.


+ Strong programming skills are required, as well as experience with MATLAB, Python, Fiji/ImageJ, or related image analysis and scientific computing environments.


+ Experience with super-resolution microscopy, single-molecule localization microscopy, single-particle tracking, fluorescence microscopy, or related advanced imaging modalities is highly desirable.


+ Experience with microscope acquisition and hardware-control software and instrumentation automation is preferred but not required.


+ The candidate must be highly motivated, organized, and able to work both independently and collaboratively, and possess strong oral and written communication skills.


+ The successful candidate should have demonstrated expertise through published papers in peer-reviewed scientific journals





This position is contingent upon grant funding.






Job Location - City, State

Philadelphia, Pennsylvania









Department / School

Perelman School of Medicine





Pay Range

$80,891.00 - $100,000.00 Annual Rate

Salary offers are made based on the candidate’s qualifications, experience, skills, and education as they directly relate to the requirements of the position, and in alignment with salary ranges based on external market data for the job’s level. Internal organization and peer data at Penn are also considered.




Equal Opportunity Statement


The University of Pennsylvania is an equal opportunity employer. Candidates are considered for employment without regard to race, color, sex, sexual orientation, religion, creed, national origin (including shared ancestry or ethnic characteristics) , citizenship status, age, disability, veteran status or any class protected under applicable federal, state or local law .




Special Requirements Background checks may be required after a conditional job offer is made. Consideration of the background check will be tailored to the requirements of the job.




University Benefits

+ Health, Life, and Flexible Spending Accounts : Penn offers comprehensive medical, prescription, behavioral health, dental, vision, and life insurance benefits to protect you and your family’s health and welfare. You can also use flexible spending accounts to pay for eligible health care and dependent care expenses with pre-tax dollars.

+ Tuition : Take advantage of Penn's exceptional tuition benefits . You, your spouse, and your dependent children can get tuition assistance here at Penn. Your dependent children are also eligible for tuition assistance at other institutions.

+ Retirement: Penn offers generous retirement plans to help you save for your future. Penn’s Basic, Matching, and Supplemental retirement plans allow you to save for retirement on a pre-tax or Roth basis. Choose from a wide variety of investment options through TIAA and Vanguard.

+ Time Away from Work: Penn provides you with a substantial amount of time away from work during the course of the year. This allows you to relax, take vacations, attend to personal affairs, recover from illness or injury, spend time with family—whatever your personal needs may be.

+ Long-Term Care Insurance: In partnership with Genworth Financial, Penn offers faculty and staff (and your eligible family members) long-term care insurance to help you cover some of the costs of long-term care services received at home, in the community or in a nursing facility. If you apply when you’re newly hired, you won’t have to provide proof of good health or be subject to underwriting requirements. Eligible family members must always provide proof of good health and are subject to underwriting.

+ Wellness and Work-life Resources : Penn is committed to supporting our faculty and staff as they balance the competing demands of work and personal life. That’s why we offer a wide variety of programs and resources to help you care for your health, your family, and your work-life balance.

+ Professional and Personal Development: Penn provides an array of resources to help you advance yourself personally and professionally.

+ University Resources: As a member of the Penn community, you have access to a wide range of University resources as well as cultural and recreational activities. Take advantage of the University’s libraries and athletic facilities, or visit our arboretum and art galleries. There’s always something going on at Penn, whether it’s a new exhibit at the Penn Museum, the latest music or theater presentation at the Annenberg Center, or the Penn Relays at Franklin Field to name just a few examples. As a member of the Penn community, you’re right in the middle of the excitement—and you and your family can enjoy many of these activities for free.

+ Discounts and Special Services : From arts and entertainment to transportation and mortgages, you'll find great deals for University faculty and staff. Not only do Penn arts and cultural centers and museums offer free and discounted admission and memberships to faculty and staff. You can also enjoy substantial savings on other goods and services such as new cars from Ford and General Motors, cellular phone service plans, movie tickets, and admission to theme parks.

+ Flexible Work Hours: Flexible work options offer creative approaches for completing work while promoting balance between work and personal commitments. These approaches involve use of non-traditional work hours, locations, and/or job structures.

+ Penn Home Ownership Services: Penn offers a forgivable loan for eligible employees interested in buying a home or currently residing in West Philadelphia, which can be used for closing costs or home improvements.

+ Adoption Assistance: Penn will reimburse eligible employees on qualified expenses in connection with the legal adoption of an eligible child, such as travel or court fees, for up to two adoptions in your household.




​


To learn more, please visit: https://www.hr.upenn.edu/PennHR/benefits-pay



The University of Pennsylvania’s special character is reflected in the wide variety of backgrounds, experiences, and perspectives of the Penn community. We seek talented faculty and staff who will constitute a vibrant community and help create an educational and working environment that best supports the University’s commitment to excellence in teaching, research, and scholarship. The University of Pennsylvania is an equal opportunity employer. Candidates are considered for employment without regard to race, color, sex, sexual orientation, religion, creed, national origin (including shared ancestry or ethnic characteristics), citizenship status, age, disability, veteran status, or any class protected under applicable federal, state or local law.

About the Company

U

University of Pennsylvania

Penn's beautiful urban campus provides easy access to a range of educational, cultural, and recreational activities. We offer excellent healthcare and tuition benefits for you and your family, as well as generous retirement benefits, professional development opportunities and flexible work options. Penn is a diverse, multicultural learning community at the cutting edge of research and information technology. Click here to read more about why we're a Best Employer. Not only does Penn offer a unique environment within the city of Philadelphia to work, we also provide a wide array of employee benefits. From a competitive retirement program and comprehensive health care options to health promotion and wellness services and tuition assistance, there's a wealth of opportunities and resources available to you at Penn.

Penn is frequently cited as an outstanding employer:

  • Recipient of the 2010 Terri Lynne Lokoff Child Care Foundation Corporate Leadership Award for commitment to supporting worklife balance programs.
  • Selected as a recipient of the 2010 Healthy Workplace Award by the Philadelphia Business Journal and presenting sponsor UnitedHealthcare
  • Recognized as a 2010 Top Workplace by The Philadelphia Inquirer/Daily News.
  • Recipient of the 2009 Vision Award for commitment to workforce diversity and economic inclusion.
  • Selected for Computerworld's 100 Best Places to Work in IT six years in a row!
  • Recognized by the Delaware Valley Association for the Education of Young Children as a 2006 Best Employer for Working Parents
  • Named a Best Place to Work in the November 2007 issue of Philadelphia Magazine.
  • Designated a Best Workplace for Commuters by the National Center for Transit Research
COMPANY SIZE
100 to 499 employees
INDUSTRY
Advertising and PR Services
FOUNDED
1990
WEBSITE
http://www.cmimedia.com/

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