Senior Research Technologist (Meeks Lab)

Department: MED-Urology

Salary/Grade: NEX/15

Target hiring range for this position will be between be range is as be $27.06-$33.50 per hour. Offered salary will be determined by the applicant's education, experience, knowledge, skills and abilities, as well as internal equity and alignment with market data.

Job Summary:

Conducts complex experimental research in a research lab, functioning as a specialist or technical expert. May manage one or more phase(s) of a major project(s) or all activities of a small project. May ensure overall lab compliance with all associated rules and regulations.

The Meeks Lab is seeking a Scientist who will oversee the operations of the laboratory, develop and manage foundational research projects in bladder cancer, especially the management of complex molecular biology techniques (single cell RNA-seq and digital spatial profiling), oversight of our mouse colony, and help in collaborations with investigators at NU. Our laboratory is vibrant, collaborative international group, fully supportive of each other to identify cures for bladder cancer. We are seeking to recruit a new laboratory manager that will make will manage daily operations of a research lab.

More specifically, the Scientist will:

• Help to supervise experiments and infrastructure of the lab, including mouse colony management, molecular biology techniques, cell culture, and genetic and protein analyses.
• Directly participate in experiments, and assist other laboratory members with cell culture experiments, single-cell RNA-seq and digital spatial profiling
• Independently plan, perform, and analyze experiments, and collaborate with PI on writing papers and grants;
• Serve as technical resource to, graduate and post-graduate trainees and provide insight, advice and guidance on experimental technologies for cancer research.
• Supervise and train lab support staff and oversee day-to-day operations of the laboratory, develops, implements & administers budgets, grant & administrative procedures.
• Assist in IACUC and laboratory research safety protocols, reviews technical operations ensuring that all processes, protocols & procedures are quality controlled & functioning up to standards

Specific Responsibilities:

• Acting as a technical expert or specialist in a particular field within a research lab, establishes and optimizes protocols and coordinates conduct of multiple complex experiments.

Molecular Biology:

• DNA, RNA, Protein isolation, purification and expression
• Southern, Northern, Western blotting
• PCR, RT-PCR
• Plasmid preparation
• Cloning, mapping and sequencing of DNA
• Recombinant virus production and purification

Cellular Biology:

• Cell culture, cell isolation
• Functional studies
• Transfection

Histology:

• Tissue fixation/processing: embedding, preparation of blocks and sectioning, staining
• Immunohistochemistry

Immunology:

• Flow cytometry
• ELISA, Elispot assay
• Cytokine assay
• Antibody production and purification

Animal:

• Husbandry
• Breeding and screening transgenic mice
• Dissections
• Blood collection
• Surgical procedures
• Database management of colony

Administration

• Oversees and manages lab databases which may include ensuring that experiments are observed and that data is collected and entered correctly.
• Reviews and analyzes data.
• Creates computer models, graphs, reports and summaries for use in publications, professional journals, and grant applications.
• Co-authors scientific papers for presentation and publication.
• Researches and obtains funding.
• Creates and maintains lab manuals regarding operating, safety, and etc. procedures.

Finance

• Creates lab financial plan and budget/audit expenses.
• Obtains sales quotes for lab equipment and supplies.
• Reviews and adjusts expenses to decrease costs.
• Oversees repair and maintenance of all lab equipment.
• Ensures that lab supplies are ready and available when necessary.

Supervision

• Trains, directs, assigns duties to and may supervise lab EEs, students, residents and/or fellows.

Miscellaneous

Performs other duties as assigned.

Minimum Qualifications:

Successful completion of a full 4-year course of study in an accredited college or university leading to a bachelors or higher degree in a scientific major or related; OR appropriate combination of education and experience and 5 years lab/bench or other relevant experience required; OR

Successful completion of a full course of study in an accredited college or university leading to a masters or higher degree in a scientific major or related; OR appropriate combination of education and experience and 3 years lab/bench or other relevant experience.

Benefits:

At Northwestern, we are proud to provide meaningful, competitive, high-quality health care plans, retirement benefits, tuition discounts and more! Visit us at https://www.northwestern.edu/hr/benefits/index.html to learn more.

Work-Life and Wellness:

Northwestern offers comprehensive programs and services to help you and your family navigate life's challenges and opportunities, and adopt and maintain healthy lifestyles.

We support flexible work arrangements where possible and programs to help you locate and pay for quality, affordable childcare and senior/adult care. Visit us at https://www.northwestern.edu/hr/benefits/work-life/index.html to learn more.

Professional Growth & Development:

Northwestern supports employee career development in all circumstances whether your workspace is on campus or at home. If you're interested in developing your professional potential or continuing your formal education, we offer a variety of tools and resources. Visit us at https://www.northwestern.edu/hr/learning/index.html to learn more.

Northwestern University is an Equal Opportunity Employer and does not discriminate on the basis of protected characteristics, including disability and veteran status. View Northwestern's non-discrimination statement. Job applicants who wish to request an accommodation in the application or hiring process should contact the Office of Civil Rights and Title IX Compliance. View additional information on the accommodations process.