The Senior Security Manager for CMS Endpoints & M365 is responsible for leading security operations, compliance, and lifecycle management for CMS-managed endpoints and the Microsoft 365 ecosystem. This role ensures the protection, integrity, and continuous security posture of desktops, mobile devices, collaboration tools, cloud productivity services, and hybrid enterprise environments supporting CMS mission operations.
The manager oversees the secure deployment, configuration, monitoring, and modernization of endpoint platforms and M365 services, while developing security standards, governance processes, and operational controls that align with CMS, HHS, FISMA, and NIST security requirements.
Key Responsibilities
Endpoint Security Operations & Compliance
Lead end-to-end security management for CMS endpoints, including Windows, Mac, and VDI.
Develop and enforce security baselines, patching standards, encryption requirements, and hardening procedures.
Maintain compliance with CMS ARS, HHS security directives, and NIST 800-53 control families through documentation, audits, and continuous monitoring.
Coordinate with CMS security leaders, ISSOs, and system owners to ensure endpoint platforms meet accreditation and risk management obligations.
M365 Security & Administration
Oversee security governance for Microsoft 365, including Exchange Online, SharePoint Online, OneDrive, Teams, and security/compliance center capabilities.
Manage conditional access, identity protections, DLP policies, threat detection, and data governance controls.
Partner with engineering and operations teams to ensure secure configuration, feature deployment, and lifecycle maintenance of the M365 environment.
Evaluate and implement security enhancements, logging strategies, and integration points across cloud and on-premise environments.
Secure Infrastructure Oversight
Lead modernization and secure deployment initiatives across CMS environments, including migration of legacy systems into protected M365 and endpoint ecosystems.
Manage sustainment of multi-site enterprise endpoint systems, ensuring availability, integrity, and compliance.
Oversee device inventory, and asset accountability processes, aligning with federal property standards.
Team Leadership & Security Governance
Work with multidisciplinary teams of system administrators, endpoint engineers, and security analysts.
Establish SOPs, workflows, and operational frameworks that enhance security posture and operational quality across the CMS endpoint and M365 landscape.
Lead cross-functional coordination involving IT, security, engineering, compliance, and governance groups.
Configuration, Patch, and Change Management
Manage secure configuration repositories and CM processes, ensuring version control, traceability, and documented baselines for endpoint and M365 systems.
Oversee secure patch deployment, software updates, vulnerability remediation, and endpoint lifecycle management.
Incident Response & Endpoint/M365 Support
Provide Tier III escalation support for endpoint and M365 incidents, outages, or security events.
Coordinate forensic reviews, root-cause analysis, and response actions related to endpoint or cloud productivity platforms.
Ensure timely communication and remediation across impacted CMS teams.
Required Qualifications
Bachelors degree in Information Technology or related field.
Extensive experience managing enterprise endpoints, secure infrastructure, or M365 environments.
Strong knowledge of Windows, VDI/thin client ecosystems, and endpoint-security tooling.
Demonstrated expertise in configuration management, security compliance, and process development.
Proven ability to lead technical teams and work collaboratively within a large federal organization.
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Original Posting:
May 13, 2026
For U.S. Positions: While subject to change based on business needs, Leidos reasonably anticipates that this job requisition will remain open for at least 3 days with an anticipated close date of no earlier than 3 days after the original posting date as listed above.
Pay Range:
Pay Range $131,300.00 - $237,350.00
The Leidos pay range for this job level is a general guideline only and not a guarantee of compensation or salary. Additional factors considered in extending an offer include (but are not limited to) responsibilities of the job, education, experience, knowledge, skills, and abilities, as well as internal equity, alignment with market data, applicable bargaining agreement (if any), or other law.