Software Developer - Bioinformatics (ETL & Object Oriented Programming)
Drug Discovery
Sequencing
Genomics
Bioinformatics
RNA
Data Analysis
SOPS
LIMS
UNIX
Big Data
ETL
Data Visualization
Datasets
Data Mining
Data Integration
Shell Scripting
Shiny
Object Oriented
Python
Object Oriented Programming
Description:
As an active team member of the Exploratory Bioinformatics group within the Computational Biology (CompBio)
research group at Boehringer-Ingelheim's US research facility in Ridgefield, CT. The successful candidate will
contribute to drug discovery efforts through analysis of multiple disease-relevant data sets, as well as development
of core informatics pipelines and data organization.
- Strong scientific understanding and experience in computer science or bioinformatics
- Work closely with internal genomics core groups and external CROs to enable data transfer/processing
workflows to enable FAIR data
- Leverage sample management, LIMS and other FAIR data resources to ensure efficient workflows
- Design, implement and/or deploy NGS data analysis workflows for data processing, visualization,
integration and mining to support novel therapeutic target identification and disease biomarker discovery
o Data Analysis: Implement methods for omics data analysis, and interpretation of genomic data
sets (e.g., bulk RNA-seq, scRNA-seq, ATAC-Seq)
o Data Visualization: Fluency in contemporary data visualization methods like R Shiny , D3
o Data Integration: Analyzing diverse datasets (multi-omics) to find relevant drug discovery targets
and downstream effects relevant to immune disease
o Data Mining: Internal, collaborative, and public databases to assist in the characterization of
Immune disease
- Select, and benchmark methods and tools, define and perform appropriate QC measures
- Apply and develop innovative analysis approaches when standard methods are not adequate
- Interpret and present analysis results to coworkers and collaborators
- Follow relevant scientific literature to ensure use of optimal methods and understand emerging practices
across the field
- Demonstrates the ability to interpret the outcome of experiments, propose appropriate follow-up, and may
propose new avenues of investigation
- Communicates own work effectively orally and in writing; contributes to writing protocols, procedures, and
technical reports
- Automate processing and results reporting and delivery
- Experience with at least one object oriented language
- Reports and treats data with a high level of integrity and ethics
- Complies with applicable regulations; Maintains proper records in accordance with SOPs and policies
- Experience working in genomics lab setting
- PhD degree (or equivalent) from an accredited institution in a related scientific discipline OR Master's
degree from an accredited institution with six-plus (6+) years of experience in a related scientific discipline
OR Bachelor's degree from an accredited institution with ten-plus (12+) years of experience in a STEM
discipline.
- The successful candidate will have experience with more than one of the following; analyzing nextgeneration
sequencing (NGS), functional genomics, statistics for big data analysis, or multi-omics data
integration
- Good knowledge of existing bioinformatics databases and file formats
- In-depth understanding of computational methods for NGS analysis and the usage of public data resources
required
- Strong hands-on skills in relevant programming languages (e.g., R, Python, Shiny, UNIX/Linux, UNIX bash
shell scripting, Nextflow), statistical software, cloud computing, visualization tools, and relevant
R/Bioconductor packages
- Demonstrated ability to produce well-designed and documented code
- Familiarity with computational biology tools and experience working with computational biologists to solve
problems
- Must enjoy working in a multi-disciplinary and collaborative environment
- Ability to troubleshoot both individually and as part of a team
- Excellent oral and written skills with the ability to communicate in an open, transparent, timely and
consistent manner
QUALIFICATION/ LICENSURE :
- Work Authorization : Green Card, US Citizen
- Travel Required : No travel required
- Shift timings: Not specified