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Biology Jobs in Cambridge, MA

Spatial Biology Scientist

The Fountain Group LLC

Cambridge, MA

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JOB DETAILS
SALARY
$46–$56 Per Hour
SKILLS
Analysis Software, Antibodies, Assay Development, Assays, Biology, Biomarkers, Budgeting, Communication Skills, Cross-Functional, Customer Acquisition, Detail Oriented, Documentation, Establish Priorities, Histology, Identify Issues, Laboratory Equipment, Microscopy, Multiplexing, Multitasking, Pathology, Problem Solving Skills, Project/Program Management, Quality Control, Regulatory Compliance, Spatial Multiplexing, Standard Operating Procedures (SOP), Team Player
LOCATION
Cambridge, MA
POSTED
3 days ago
Currently I have an opening for a Scientist located in Cambridge, MA. Details for the position are as follows:
 
Pay Range: $46-$56/hour

Job Description:
  • 23-month contract with the possibility of extending or converting to permanent based on performance and budget.
  • We are seeking an experienced scientist with deep, hands-on expertise in histology and antibody validation to join a fast-paced and highly collaborative scientific environment. This role will support multiple ongoing spatial omics projects including biomarker discovery and target validation initiatives requiring someone who is highly adaptable, detail-oriented, and comfortable balancing planned work with urgent, short-term requests. The ideal candidate thrives in a dynamic environment, approaches shifting priorities as an opportunity, and can deliver high-quality work across a broad range of histology and multiplex imaging workflows.
  • Contribute to and help shape DAGS multiomics and spatial biology experimental strategies.
  • Support the maintenance, troubleshooting, and optimization of histology instruments and associated laboratory workflows. Maintain, calibrate, and document the use of laboratory equipment in compliance with internal standards.
  • Perform routine and advanced preparation of histological slides from FFPE blocks, including embedding, sectioning, staining, labeling, and quality assessment.
  • Perform antibody validation using chromogenic and multiplex immunofluorescence approaches to support assay development and target validation.
  • Design, optimize, and validate multiplex immunofluorescence panels using the Lunaphore COMET platform and execute assigned projects with accuracy and timeliness.
  • Collaborate with cross-functional and cross-departmental teams to support target evaluation, assay troubleshooting, and technology implementation.
  • Manage multiple priorities effectively in a fast-paced setting while maintaining scientific rigor and attention to detail.
  • Contribute ideas for workflow improvements, assay optimization, and adoption of Client technologies.
Essential Requirements:
  • BS with 6years or M.Sc. with 4years or PHD with 2years in a relevant scientific discipline with significant hands-on experience in histological techniques.
  • Demonstrated expertise in antibody validation using chromogenic and multiplex immunofluorescence staining methods.
    Familiarity with automated staining platforms, preferably the Leica BOND system.
  • Strong experience in high-plex spatial biology and multiplex immunofluorescence methodologies, including platforms such as Lunaphore COMET, CODEX, CellScape, and imaging mass cytometry.
  • Experience operating microscopy systems and modern slide scanners such as Leica GT450, Akoya PhenoImager, or Zeiss Axioscan.
  • Proficiency with image visualization and analysis software, such as HALO, QuPath, and ImageJ.
  • Strong scientific judgment, critical thinking, and problem-solving skills.
  • Excellent communication and collaboration skills, with the ability to work effectively across teams.
  • Curiosity, adaptability, and a proactive mindset toward learning and implementing new technologies.
Preferred Qualifications:
  • Experience with assay development, optimization, and troubleshooting in a research or translational setting.
  • Familiarity with tissue biomarker evaluation, spatial tissue profiling, or pathology-adjacent workflows.
  • Experience documenting and standardizing workflows, SOPs, and QC procedures.
  • Ability to independently prioritize requests and manage multiple concurrent projects.
  • Demonstrated experience working in a matrixed, interdisciplinary environment.
  • Exposure to data interpretation and presentation of histology or imaging-based results to scientific stakeholders.
 
 
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About the Company

T

The Fountain Group LLC

The Fountain Group provides Contingent Labor, Statement-of-Work, and Contingent-to-Permanent resources to clients with an internal/external Contingent Labor Managed Service Program or Clients without a program. The Fountain Group is committed to the belief that we all share in the responsibility to conduct our businesses in a socially and environmentally responsible manner. We base this on the premise that a company is much more than the products it offers. The effect a company has on the environment, the people and the communities it serves reflects the company’s dedication to being not only a good business, but to being a good corporate citizen. The Fountain Group believes the key to servicing a client is to identify the client demand precisely. Therefore, The Fountain Group focused its efforts on building and developing a process, which can identify an exact match for our client’s needs. Our process utilizes modern technology combined with 30+ years of Talent Acquisition experience to deliver Precision resources. Financial strength is prominent among The Fountain Group’s corporate values. The future of our business will be built on the innovation, compassion, outstanding services and technology, but a solid financial foundation is required to carry us forward to meet our business goal and support our long term vision.

COMPANY SIZE
500 to 999 employees
INDUSTRY
Staffing/Employment Agencies
WEBSITE
https://www.thefountaingroup.com/

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