Sr. Clinical Data Manager

Karwell Technologies
  • Lake county, IL
  • Quick Apply
30+ days ago

Job Description

Responsibilities:
  • Clinical Data Manager will be responsible for all aspects of clinical trial data management from study start up through database lock and study close.
  • This includes the EDC build and user acceptance testing (UAT), study data cleaning and reconciliation, query issue and resolution, and database locks.
  • They will ensure optimized data collection, flow and access across EDC and non-EDC data sources.
  • They are also responsible for accuracy, consistency, completeness and CDISC compliance of all clinical databases.
  • The role will operate as a key member of the Clinical Operations team.
  • Develop and maintain all data management documentation, including case report forms, data management plans, edit check specifications, data review plans and data transfer agreements.
  • Design case report forms (CRFs) for electronic data capture (EDC) systems for data collection.
  • Perform data entry and cleaning activities, including discrepancy management and query resolution.
  • Conduct data validation checks and implement quality control measures to ensure accuracy and completeness.
  • Collaborate with study team members to resolve data-related issues and discrepancies.
  • Generate and review data listings, summaries and reports for data review.
  • Serve as a primary or backup resource for issues about data management.
  • Ensure compliance with guidelines, Good Clinical Practice (GCP), CDISC standards and other relevant regulations.
  • Contribute to the development and validation of data management software tools.
Requirements:
  • BSc or MSc in Life Sciences, Data/Computer Science, Bioinformatics or equivalent industry experience.
  • 5-7 years of data management experience in the pharmaceutical or biotechnology industries.
  • Strong expertise in project/program management including stakeholder management.
  • Knowledge of industry standards (CDISC, SDTM, CDASH).
  • In-depth understanding of Data Management regulatory guidelines: ICH, GCDMP, 21CFR Part 11.
  • Proven ability to pre-emptively identify data and system issues and mitigate risks to data quality.
  • Knowledge and experience with development, validation, execution, maintenance, documentation, and archival of clinical data.
  • Experience in development and implementation of Clinical data management standards and procedures.
  • Experience with web-based EDC, clinical data management systems and medical coding dictionaries such as MedDRA and WHO Drug.

Numbers & Facts

LocationLake county, IL

Skills

  • Acceptance Testingunmatched
  • Bioinformaticsunmatched
  • Biologyunmatched
  • Biotech and Pharmaceuticalunmatched
  • Case Report Form (CRF)unmatched
  • Clinical Dataunmatched
  • Clinical Data Interchange Standards Consortium (CDISC)unmatched
  • Clinical Data Managementunmatched
  • Clinical Information Systemsunmatched
  • Clinical Practices/Protocolsunmatched
  • Clinical Trial Managementunmatched
  • Code of Federal Regulationsunmatched
  • Computer Scienceunmatched
  • Data Cleaningunmatched
  • Data Collectionunmatched
  • Data Entryunmatched
  • Data Managementunmatched
  • Data Qualityunmatched
  • Document Archivingunmatched
  • Documentationunmatched
  • Electronic Data Capture (EDC)unmatched
  • GCP (Good Clinical Practices)unmatched
  • ICH Regulationsunmatched
  • Industry Standardsunmatched
  • Maintain Complianceunmatched
  • Medical Codingunmatched
  • Medical Dictionary for Regulatory Activities (MedDRA)unmatched
  • Problem Solving Skillsunmatched
  • Project/Program Managementunmatched
  • Quality Controlunmatched
  • Quality Metricsunmatched
  • Reconciliationunmatched
  • Regulationsunmatched
  • Risk Managementunmatched
  • Software Validationunmatched
  • Startupunmatched
  • Validation Testingunmatched

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