Sr Director, Government Accounts

Definium Therapeutics is a late-stage clinical biopharmaceutical company and our mission is to forge a new era of psychiatry by applying scientific rigor to psychedelics, with the goal of developing accessible treatments that unlock healing at scale.

Our lead product candidate, lysergide tartrate (our proprietary orally disintegrating tablet form of lysergide (LSD) D-tartrate), represents a highly differentiated, potential best-in-class opportunity for patients suffering from generalized anxiety, major depressive disorder, and posttraumatic stress disorder. Our early stage pipeline includes DT402, the R-enantiomer of MDMA and is under development to target the core symptoms of autism spectrum disorder (ASD), specifically addressing social communication challenges.

Guided by the recognition that patients deserve more than better, Definium is relentlessly advancing a new generation of therapeutics intended to address the underlying causes of psychiatric and neurological disorders. By turning evidence into impact, Definium aims to change the trajectory of today's mental health care crisis and enable a healthier future. Headquartered in New York, Definium Therapeutics trades on Nasdaq under the symbol DFTX.

Together we are moving psychiatry forward-beyond better, into a boundless future. Join us!

The Senior Director, Government Accounts implements Definium's government and public-sector payer access strategy across assigned Medicaid, Medicaid managed care, and other priority public payer channels. This role develops account-specific recommendations, supports launch readiness, and translates clinical, economic, operational, and policy considerations into practical access plans. As assigned, the role may also support Kaiser Permanente and similar integrated payer-provider organizations.

Primary Responsibilities

• Implement government access strategy across Medicaid fee-for-service, Medicaid managed care, and priority public payer channels
• Develop account plans that address state review timelines, policy requirements, coverage pathways, and reimbursement considerations
• Build relationships with state Medicaid agencies, Medicaid MCOs, pharmacy and medical policy leaders, and public payer stakeholders
• Identify and address access barriers, including policy criteria, utilization management, reimbursement, benefit design, and operational readiness
• Partner with Government Affairs to monitor federal and state policy developments affecting access, coverage timing, or payer review
• Support Kaiser Permanente and similar integrated payer-provider planning as assigned
• Collaborate with Finance, Legal/Compliance, and cross-functional partners on public payer access planning, policy considerations, and launch readiness
• Partner with HEOR, Medical Affairs, and Value & Access to support payer-relevant evidence, value communication, and launch readiness materials
• Generate customer insights and market intelligence to inform account planning, launch readiness, and leadership decision-making
• Operate as a player/coach by supporting account planning and directly engaging priority accounts where senior-level access expertise is required

Primary Customers

• State Medicaid agencies and Medicaid fee-for-service programs
• Medicaid managed care organizations and pharmacy/medical policy leaders
• State pharmacy and medical directors, DUR/P&T stakeholders, and public payer clinical decision-makers
• CMS and federal policy stakeholders, as appropriate and in coordination with Government Affairs
• Kaiser Permanente and similar integrated payer-provider organizations, as assigned
• Government policy organizations and external access influencers relevant to coverage and reimbursement readiness

Required Qualifications

• Bachelor''s degree required; advanced degree preferred
• Minimum 10 years in government/public payer market access, including Medicaid, managed Medicaid/MCOs, Medicare, and/or state health programs
• Expertise navigating state-level policy, legislative, and regulatory processes affecting drug access and reimbursement
• Experience with Medicaid PDLs, supplemental rebates, and state P&T or DUR processes
• Track record contributing account-level insights and recommendations to government affairs or market access planning
• Relationships with state Medicaid directors, state pharmacy directors, or Medicaid MCO leadership a plus
• Working knowledge of public payer access considerations, Medicaid policy requirements, and state-level coverage and reimbursement processes
• Ability to synthesize state-by-state policy variation into clear account and national recommendations
• Experience with Kaiser Permanente or similar integrated payer-provider organizations preferred
• Cross-functional collaboration with government affairs, policy, legal/compliance, HEOR, medical, finance, and commercial operations teams
• People/team leadership experience; willingness to travel, typically 50%+
• Knowledge of relevant compliance requirements, including anti-kickback statute, False Claims Act, and state-specific transparency laws

Compliance and PIE-Aligned Communications

Payer communications, including appropriate pre-approval information exchange and healthcare economic information, will be conducted in alignment with approved company materials, Medical/Legal/Regulatory review processes, applicable FDA guidance, PIE guidelines, and company compliance policies. This role will partner closely with internal stakeholders to ensure payer planning discussions are accurate, consistent, and appropriately aligned with approved access, value, and launch readiness objectives.

The starting base pay range for this position is $220,000.00 - $280,000.00. Compensation will be determined based on several factors including, but not limited to, skill set, years of experience, and the employee's geographic location.

Employees in this role may be entitled to additional compensation, including bonus and equity. Benefits information is listed on our Jobs Page. The Company provides competitive benefits to employees including:

• 100% paid health benefits including Medical, Dental and Vision for you and your dependents
• 401(k) program with company match and vesting after the turn of the first month after your start date
• Flexible time off
• Generous parental leave and some fun fringe perks!