Sr. Manager, Environmental Health & Safety

HistoSonics is a commercial-stage medtech company advancing the Edison System, a novel non-invasive sonic beam therapy based on histotripsy. Since receiving FDA De Novo grant for the non-invasive destruction of liver tumors in 2023, the company has progressed beyond initial market entry into commercial expansion, reimbursement momentum, and ongoing clinical and pipeline development. In addition to its current liver tumor indication, HistoSonics is pursuing future indications across multiple applications including kidney, pancreas, prostate, neuro, women's health, and other significant underserved human health areas, to realize the broader potential histotripsy across multiple disease states and medical specialties.

We offer an exciting work culture where cutting-edge science meets real-world application, and each team member's contribution is important to our success in ensuring our physicians and their patients get what they need most.

Location: Plymouth, MN

Position Summary (Why this role matters):

The Senior Manager, Environmental Health & Safety (EHS) is responsible for building and leading HistoSonics' EHS program across all domestic sites, with growing responsibility for international locations as the company expands globally. This role ensures that HistoSonics maintains a safe, compliant, and well-governed working environment for employees, contractors, and visitors, while supporting the company's operations as a fast-scaling medical device manufacturer.

Reporting to the Director, Facilities & Real Estate, this role partners closely with Facilities, Manufacturing, R&D, Quality, Regulatory and HR to embed safety and environmental compliance into daily operations. The Senior Manager is both a program builder and a hands-on practitioner - equally comfortable developing policy and standards as they are walking the floor, identifying hazards, and coaching teams on safe practices.

Key Responsibilities (What you'll do):

EHS Program Strategy & Governance

• Develop, implement, and continuously improve a comprehensive EHS program covering occupational safety, industrial hygiene, environmental compliance, and emergency preparedness across all domestic sites.
• Establish EHS policies, standards, and procedures aligned with applicable federal, state, and local regulations (e.g., OSHA, EPA) and relevant industry standards for medical device manufacturing.
• Build the foundation for a global EHS framework that can extend to international sites as HistoSonics scales, ensuring consistency in core safety standards while accommodating local regulatory requirements.
• Define and track key EHS performance metrics; report program performance, trends, and risk areas to senior leadership on a regular cadence.

Workplace Safety & Risk Management

• Develop and oversee core occupational safety programs, including Lockout/Tagout, Machine Guarding, Hazard Communication, Chemical Hygiene, Electrical Safety, and Contractor Safety.
• Conduct regular safety audits, job hazard analyses, and risk assessments across manufacturing, lab, warehouse, and office environments; drive corrective and preventive actions to closure.
• Lead investigation of workplace incidents, near-misses, and injuries; identify root causes and implement systemic improvements to prevent recurrence.
• Own the company's industrial hygiene program, including exposure monitoring, ergonomic assessments, and personal protective equipment (PPE) standards.
• Partner with Facilities and Manufacturing leadership to ensure equipment, processes, and site layouts meet safety design and operational requirements.

Regulatory Compliance & Reporting

• Ensure compliance with all applicable occupational safety and environmental regulations; maintain required permits, certifications, and recordkeeping (e.g., OSHA 300 logs, environmental permits, hazardous waste manifests).
• Serve as the primary point of contact for EHS-related regulatory inspections and audits, including preparation, on-site representation, and response to findings.
• Manage hazardous materials and waste programs in compliance with applicable regulations, including proper storage, handling, labeling, and disposal practices.
• Maintain effective chemical inventory and Safety Data Sheet management systems across applicable locations.
• Stay current on evolving EHS regulations and industry best practices; proactively assess and communicate the impact of regulatory changes on HistoSonics' operations.

Emergency Preparedness & Business Continuity

• Develop and maintain site-specific emergency response plans, including fire, severe weather, and other site-relevant emergency scenarios.
• Lead emergency response training and drills (e.g., evacuation drills, fire safety training) across all sites; ensure designated emergency personnel are trained and ready.
• Partner with Facilities to support the readiness, testing, and ongoing effectiveness of life-safety systems and related emergency infrastructure.
• Partner with Facilities on business continuity planning related to safety and environmental risks at each site.

Training, Culture & Stakeholder Engagement

• Design and deliver EHS training programs for employees, contractors, and new hires, ensuring role-appropriate safety knowledge across the organization.
• Champion a strong safety culture across HistoSonics, partnering with site leaders and team members to embed safety as a shared responsibility rather than a compliance checkbox.
• Establish and facilitate employee safety committees or other structured forums for identifying risks, sharing feedback, and advancing safety improvements.
• Collaborate with Manufacturing, R&D, Quality, Facilities, and HR to integrate EHS considerations into process design, facility planning, and workforce policies.
• Represent EHS in cross-functional projects, including new site buildouts, equipment installations, and process changes, ensuring safety is considered early in planning.

Qualifications and Skills:

Required

• Bachelor's degree in Occupational Health and Safety, Environmental Science, Engineering, or a related field, or equivalent professional experience.
• 10+ years of progressive experience in environmental health and safety, with demonstrated ownership of an EHS program in a manufacturing, industrial, or life sciences environment.
• Strong working knowledge of OSHA, EPA, and other applicable federal, state, and local EHS regulations.
• Experience in a medical device, or other regulated manufacturing environment.
• Experience leading incident investigations, root cause analysis, and corrective action programs.
• Demonstrated experience managing hazardous materials and waste programs in a regulated environment.
• Demonstrated experience serving as a Radiation Safety Officer or supporting radiation-safety programs, including familiarity with applicable state and federal requirements.
• Strong project management skills with experience leading cross-functional safety initiatives.
• Excellent communication and training skills, with the ability to influence safety behavior at all levels of the organization.

Preferred

• Certified Safety Professional (CSP), Certified Industrial Hygienist (CIH), Certified Hazardous Materials Manager (CHMM), or similar professional certification.
• Experience building or scaling an EHS program in a high-growth company.
• Exposure to international EHS regulatory frameworks or experience supporting global site expansion.
• Experience partnering closely with Facilities and Manufacturing functions on integrated safety planning.

Benefits: We offer a comprehensive benefits package for full-time employees. This includes health, dental, and vision insurance, life, short-term and long-term disability insurance, 401(k), paid time off, and more.

We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

U.S. Work Authorization & Sponsorship: Employer will not sponsor visas for position.

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