Sr. Science & Health Advisor, Guidelines, AHA/ACC

Overview

Since our founding in 1924, we''ve cut cardiovascular disease deaths in half, but there is still so much more to do. To overcome today's biggest health challenges and accelerate this progress, we need passionate individuals like you. Join our movement, be part of the progress, and help ensure a healthier future for all. You matter, and so does the impact you can make with us.

The American Heart Association has an excellent opportunity for a Senior Science and Health Advisor, Guideline Methodology.

The Senior Science and Health Advisor, Guideline Methodology, serves as a scientific and operational leader for the development, application, and continuous improvement of the American Heart Association/ACC clinical guideline methodology. This role will drive error-free methodological rigor and will also demonstrate success in ensuring consistency across guideline products and leading innovation in evidence review processes, including AI-enabled approaches. The incumbent also collaborates across leadership, guideline advisors, and volunteer committees to advance high-quality, efficient guideline development.

The Association offers many resources to help you maintain work-life harmonization through your changing needs and life situations. To help you be successful, you will have access to Heart U, our award-winning corporate university, as well as additional training and support, locally.

#TheAHALife is more than a company culture; it is our way of life. It embodies our commitment to work-life harmonization and is guided by our core values where our employees can thrive both personally and professionally. Discover why you will Be Seen. Be Heard. Be Valued at the American Heart Association by following us on LinkedIn, Instagram, Facebook, X, and at heart.jobs.

Responsibilities

• Lead and evolve guideline methodology

• Oversee the development, application, and continuous improvement of American Heart Association/ACC guideline methodology, ensuring consistency, rigor, and alignment across all guideline product

• Maintain and update the American Heart Association/ACC Guideline Methodology and Policies Manual to reflect current standards and best practices

• Champion AI-enabled guideline development

• Lead the AI-LLM-first strategy for guideline development, including design, development, and deployment of AI agents/workflows for evidence review, data extraction, and content drafting; oversee prompt engineering, validation, and continuous optimization

• Partner with the American Heart Association/ACC National Senior Director to scale AI-enabled methodologies across guideline advisors and volunteer committees

• Provide methodological oversight across guideline development

• Conduct a comprehensive methodological review of recommendations, evidence grading (COR/LOE), and associated figures throughout key development milestones, including peer review

• Ensure consistent and appropriate application of methodological standards, including evidence classification, FDA considerations, and cost-effectiveness analyses

• Ensure consistent, error-free application of methodological standards across all guideline documents, minimizing variability and post-review corrections

• Lead guideline projects and pragmatic updates

• Serve as a primary liaison and project lead for guidelines undergoing pragmatic updates, ensuring alignment with methodological standards, timelines, and Joint Committee expectations

• Coordinate across scientific, operational, and volunteer stakeholders to deliver high-quality outputs on schedule

• Oversee relationships with industry (RWI) implementation and compliance

• Supervise the Compliance Operations Manager for RWI processes, ensuring highly accurate, error-free documentation, timely disclosures, and adherence to the American Heart Association/ACC RWI procedure.

• Monitor and ensure full compliance with the joint documents, committees, and contributors.

• Oversee documentation and processes that ensure audit readiness and consistency across the full guideline portfolio

• Develop and train guideline contributors

• Design and deliver training programs (synchronous and asynchronous) for writing committee members and reviewers on guideline methodology and evidence evaluation frameworks

• Promote adoption of best practices in evidence review and recommendation development

• Supervise and develop staff

• Manage and mentor direct reports, ensuring effective project execution, professional development, and alignment with organizational priorities

• Support staff in navigating complex volunteer and guideline development environments

• Contribute to team and organizational priorities

• Support cross-functional initiatives and evolving priorities related to guideline methodology and innovation

Qualifications

• Bachelor's degree in Public Health, Epidemiology, or a related health, life science, or medical research discipline
• 5+ years of relevant experience
• 5+ years of experience in medical writing, scientific editing, guideline development, or clinical research
• 3-5 years of experience supporting or overseeing clinical guideline development and/or methodology application
• 2-5 years of experience managing direct reports or leading staff/project teams
• Demonstrated expertise and success in comprehensive evidence review, evidence synthesis, and development of evidence tables
• Strong understanding of clinical research methods, evidence grading frameworks (e.g., COR/LOE), and guideline development processes
• Proven ability and success in managing multiple complex projects simultaneously in a deadline-driven environment
• Excellent written and verbal communication skills, including advanced editing and proofreading proficiency
• Strong interpersonal and leadership skills, with experience working with cross-functional teams, volunteer experts, and senior stakeholders
• Proficiency with Microsoft Office, reference management tools (e.g., EndNote), Adobe Acrobat, and workflow/content management platforms
• Ability to travel approximately 5-10%, including occasional overnight travel.

Preferred Qualifications

• Advanced degree (e.g., MPH, MS, PhD) in Public Health, Epidemiology, or a related field
• Extensive experience contributing to clinical practice guidelines, scientific statements, or other evidence-based publications
• Experience developing or applying guideline methodology frameworks at scale
• Experience leading or implementing AI-enabled or technology-driven approaches to evidence review or content development
• Experience working in a professional association, academic, or clinical organization with volunteer committee structures
• Familiarity with workflow/project management tools and structured content management systems

Compensation & Benefits

The expected pay range will be $110,000 - $115,000. Pay is commensurate with experience; geographic differentials to the pay range may apply. The American Heart Association reserves the right to pay more or less than the posted range.

The American Heart Association invests in its people. Here are the main components of our total rewards package. Visit Rewards & Benefits to see more details.

• Compensation - Our goal is to ensure you have a competitive base salary. That's why we regularly review the market value of jobs and make adjustments, as needed.
• Performance and Recognition - You are rewarded for achieving success through annual salary planning and incentive programs; based on the type of position
• Benefits - We offer a wide array of benefits including medical, dental, vision, disability, and life insurance, along with a robust retirement program that includes an employer match and automatic contribution. As a mark of our commitment to employee well-being, we also offer an employee assistance program, employee wellness program and telemedicine, and medical consultation.
• Professional Development - You can join one of our many Employee Resource Groups (ERG) or be a mentor/mentee in our professional mentoring program. Heart U is the Association's national online university, with more than 100,000 resources designed to meet your needs and busy schedule.
• Work-Life Harmonization - The Association offers Paid Time Off (PTO) at a minimum of 16 days per year for new employees. The number of days will increase based on seniority level. You will also have a total of 12 paid holidays off each year, which includes several days off at the end of the year.
• Tuition Assistance - We support the career development of all employees. This program provides financial assistance to employees who wish to further their education and career in relation to their current duties and responsibilities, or for potential future positions in the organization.

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