Job Description Summary
The de Cubas Laboratory at the Hollings Cancer Center at Medical University of South Carolina is recruiting a Research Specialist I to contribute to cutting-edge research at the intersection of cancer biology and immunology. Our work focuses on understanding how genetic alterations such as SETD2 loss influence tumor immunogenicity and therapeutic response. By combining molecular biology cell-based systems and mouse models we seek to translate mechanistic discoveries into strategies that improve cancer treatment.
The selected candidate will be responsible for the maintenance and logistical organization of a basic science laboratory with particular emphasis on performing cell and molecular biology techniques and ordering and maintaining lab supplies. We seek a highly motivated individual with previous experience in western blotting RT-qPCR and cell culture.
Medical University of South Carolina MUSC - UnivWorker TypeEmployeeWorker Sub-TypeResearch GrantCost CenterCC001034 COM PHARM Operations CCPay Rate TypeHourlyPay GradeUniversity-GEN06Pay Range37200.00 - 48300.00 - 59500.000Scheduled Weekly Hours40Work Shift
Job Description Research Specialist I - The de Cubas Lab MUSCHollings Cancer CenterPercent Effort
This Research Specialist I position will involve providing technical assistance to the Principal Investigator in cancer research studies as well as assist in lab operations. Specific tasks will be as follows:
• Perform a number of molecular biology procedures (35) • Molecular biology experimentation employing various techniques such as isolation and purification of proteins and nucleic acids. • Proteins will be further analyzed by immunoblot analysis. • Cell culture and in vitro functional assays (30) • Maintaining cell lines and performing various assays. • Assist with daily lab operations (25) • The selected candidate will assist with daily lab operations including stocking consumable items and reagents making buffers and aliquoting reagents. • Perform routine maintenance of and experimentation in mice (10) • These responsibilities include weighing and measuring mice and treating with compounds. • Assists PI in ensuring that lab personnel adhere to IACUC animal protocol. • Aid in IACUC inspections.
Required Minimum Education and Experience
MUSC Minimum Training and Experience Requirements
A high school diploma and two years work experience in a clinical or research setting a bachelors degree in chemistry biology or other natural life or health care science may be substituted for the two years of required experience. Preferred Knowledge Skills and Abilities
Previous experience in a laboratory. Strong organizational record keeping interpersonal and communication skills required. Must be able to perform calculations to follow experimental procedures and methods and develop independence with tasks and experiments. Prior experience working with mice is valued. Some weekend holidays and/or evenings may be required. Must be organized and have attention to detail. All personnel are expected to maintain laboratory notebook.
Position Start Date: April 2025
Additional Job Description
Minimum Requirements A high school diploma and two years work experience in a clinical or research setting a bachelors degree in chemistry biology or other natural life or health care science may be substituted for the two years of required experience. Physical Requirements
Note: The following descriptions are applicable to this section
Continuous - 6-8 hours per shift Frequent - 2-6 hours per shift Infrequent - 0-2 hours per shift
Ability to perform job functions in an upright position. Frequent Ability to perform job functions in a seated position. Continuous Ability to perform job functions while walkingmobile. Frequent Ability to climb using step stool. Infrequent Ability to work in temperature extremes 32° F to 100° F when required due to assignments in cold rooms and/or foreign countries. Infrequent Ability to work in confined/cramped spaces. Continuous Ability to bend at the waist. Frequent Ability to twist at the waist. Frequent Ability to fully use both hands/arms. Continuous Ability to perform repetitive motions with hands/wrists/elbows and shoulders. Frequent Ability to fully use both legs. Frequent Ability to reach in all directions stretch/bend while moving items/materials from both sitting and standing positions. Frequent Ability to maintain good olfactory sensory function/distinction. Continuous Ability to lift materials up to 20 lbs. unassisted. Infrequent Ability to lift and carry 4 liter waste material bottles a distance of 30 feet unassisted. Frequent Ability to lift and carry 25-30 lbs. jugs of liquid a distance of 100 feet unassisted. Infrequent Ability to lift file boxes from floor level to counter tops unassisted. Frequent Ability to push Ability to lift 40 lbs. centrifuge rotors from floor level to height of 40 inches then down 20 inches into centrifuge drum unassisted. Infrequent Ability to lift 25 lbs. boxes from floor level to maximum height of 72 inches unassisted. Infrequent Ability to push/pull file boxes from one location to another at floor level. Frequent Ability to maneuver heavy equipment on bench tops 50 lbs. or greater unassisted. Frequent Ability to perform gross motor functions with frequent fine motor movements. Continuous Ability to maintain 2040 vision corrected in one eye or with both eyes. Continuous Ability to match or discriminate between colors normally. Continuous Ability to hear and recognize various alarms emitting from work area systems. Continuous Ability to hear and/or understand conversations. Continuous Ability to work in a darkroom for processing film etc. Continuous Ability to be qualified physically for respirator use initially and annually. Continuous Additional New Requirements
Ability to work rotating shifts as required. Ability to work overtime as required. Ability to learn and use new processes tools and equipment as required.
If you like working with energetic enthusiastic individuals you will enjoy your career with us
The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race color religion or belief age sex national origin gender identity sexual orientation disability protected veteran status family or parental status or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications merit and business need. Medical University of South Carolina participates in the federal E-Verify program to confirm the identity and employment authorization of all newly hired employees. For further information about the E-Verify program please click here http://www.uscis.gov/e-verify/employees