Wet Lab Scientist II

Position Overview:

MyOme is seeking a Scientist II to join our research wet lab team and help drive the development, optimization, and validation of next-generation sequencing (NGS) assays. You will work closely with Clinical Operations, Bioinformatics, and Quality teams to bring new sequencing-based tests from concept through verification and validation.

What You'll Do:

• Plan and execute structured development experiments including optimization, titrations, and bridging studies 
• Contribute to transitioning workflows from R&D into standardized or regulated environments (e.g., CLIA/CAP-ready processes)
• Collaborate with the bioinformatics team to analyze results including QC metrics, run acceptance criteria, and end-to-end workflow performance to drive data-informed decisions
• Author and review SOPs, batch records, validation plans and validation reports
• Evaluate new reagents, instruments, and technologies and recommend adoption where appropriate

What You'll Need:

• M.S. with 4+ years, or B.S. with 6+ years of hands-on wet lab experience in molecular biology, genomics, biochemistry, or a related discipline. Ph.D. with 1+ years of relevant industry experience also considered.
• Proven, hands-on experience developing or optimizing NGS assays (e.g. whole-genome sequencing, RNASeq, etc.) end-to-end — from extraction through library prep, sequencing, and QC interpretation.
• Preference for R and Python experience to analyze downstream results
• Proficiency with sequencing platforms (e.g., Illumina, ONT, PacBio) and common library preparation chemistries.
• Strong working knowledge of DNA/RNA quantification and QC tools (e.g. Qubit, TapeStation/Bioanalyzer).
• Skilled at experimental design and troubleshooting with strong documentation habits

Location, Compensation, and Benefits:

• Location: Onsite at our Menlo Park, CA laboratory campus.
• Compensation: Annual salary range of $130,000 - $160,000, based on experience.