Vice President of Business Development Holt BrothersVice President of Business DevelopmentRaleigh, NCThe Vice President of Business Development will serve as a vital member of the executive team, responsible for identifying and pursuing new business opportunities, cultivating and maintaining relationships with key clients, and coordinating with internal teams to ensure successful project delivery. Holt Brothers Construction is an award-winning, Carolina-based, full-service construction firm focused on delivering thoughtful, high-quality projects with an emphasis on client service, community engagement, and teamwork.
Assembly Technician Graham Personnel ServicesAssembly TechnicianMebane, NC$18–$24 / hourOnce assembly is complete, you will transport the units to the packaging area using motorized overhead cranes or forklifts and assist in loading them onto flatbed trucks for shipping. Position Overview : You will be responsible for assembling large and complex cooling systems based on detailed work order instructions and 3D computer models.
Pipewelder - RTP EASPipewelder - RTPRaleigh, North CarolinaAll welders under the trade of piping are required to pass certifications tests on; Carbon Steel Schedule 40 Pipe, open root joint, and in the 6G, fixed position. Welds performed must meet ASME Sec IX Boiler and Pressure Vessel Code requirements.
Product Manager (Truss Software) Illinois Tool WorksProduct Manager (Truss Software)Any City, NC$90,000–$140,000 / yearDivision Description: Alpine, an ITW company, is a leading provider of industry solutions and increased business productivity for component manufacturers helping design and manufacture the highest quality roof, floor and wall components. The company's seven industry-leading segments leverage the ITW Business Model to generate solid growth with best-in-class margins and returns in markets where highly innovative, customer-focused solutions are required.
Senior Maintenance Technician - Utilities (Waste Water Treatment) - Day Shift Amgen IncSenior Maintenance Technician - Utilities (Waste Water Treatment) - Day ShiftHolly Springs, NCThe Senior Operator/Mechanic works independently to maintain treatment system performance, monitor permit compliance parameters, and perform mechanical and electrical maintenance on wastewater treatment equipment including pumps, mixers, chemical feed systems, Dissolved Air Flotation (DAF) systems, instrumentation, controls, and associated utilities. In addition to the base salary, Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including: Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
Senior Maintenance Technician – Utilities (Waste Water Treatment) – Day Shift AmgenSenior Maintenance Technician – Utilities (Waste Water Treatment) – Day ShiftHolly Springs, North CarolinaThe Senior Operator/Mechanic works independently to maintain treatment system performance, monitor permit compliance parameters, and perform mechanical and electrical maintenance on wastewater treatment equipment including pumps, mixers, chemical feed systems, Dissolved Air Flotation (DAF) systems, instrumentation, controls, and associated utilities. In addition to the base salary, Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including: Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
Front Line Manufacturing Manager - Upstream Bulk Drug Substance - Days Amgen IncFront Line Manufacturing Manager - Upstream Bulk Drug Substance - DaysHolly Springs, NCIn addition to the base salary, Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including: Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. This essential role will lead a team responsible for manufacturing cell culture operations including seed train, SUBs, Perfusion, RTF, Stainless Steel BRXs, Depth Filtration and Centrifugation, while partnering across functions to ensure successful operational readiness, technology transfer, and ramp‑up of manufacturing operations within the new facility.
Senior Specialist – Contamination Control and Investigations AmgenSenior Specialist – Contamination Control and InvestigationsHolly Springs, North CarolinaWhen completed, the Amgen FleX batch facility will combine the latest in single use technologies with traditional stainless steel equipment to allow for maximum flexibility in operations The FleX Batch facility will not only feature the best in-class drug substance manufacturing technologies with embedded industry 4.0 capabilities, but it will also integrate sustainability innovations to reduce carbon and waste, as part of Amgen's plan to be a carbon-neutral company by 2027. In addition to the base salary, Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including: Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
Specialist Manufacturing New Product Introduction (NPI): Upstream Readiness AmgenSpecialist Manufacturing New Product Introduction (NPI): Upstream ReadinessHolly Springs, North CarolinaIn addition to the base salary, Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including: Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. Responsibilities: New Product Introduction (NPI) lead coordinating with Manufacturing, Process Development, Supply Chain, Planning, Facilities and Engineering, Quality, and other teams to introduce new Drug Substance products and/or advanced technologies into the plant using project management tools.
Front Line Manufacturing Manager - Bulk Drug Substance Services - Days AmgenFront Line Manufacturing Manager - Bulk Drug Substance Services - DaysHolly Springs, North CarolinaThisessentialrole will lead a team responsible for manufacturingoperations including Raw Material and Solution Logistics, Weighing and Dispensing, Buffer/Media Solution Preparation, Parts Washer, and Autoclave, and material handling,while partnering across functions to ensure successful operational readiness, technology transfer, and ramp‑up of manufacturing operations within the new facility. In addition to the base salary, Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including: Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
Senior Specialist - Contamination Control and Investigations Amgen IncSenior Specialist - Contamination Control and InvestigationsHolly Springs, NCWhen completed, the Amgen FleX batch facility will combine the latest in single use technologies with traditional stainless steel equipment to allow for maximum flexibility in operations The FleX Batch facility will not only feature the best in-class drug substance manufacturing technologies with embedded industry 4.0 capabilities, but it will also integrate sustainability innovations to reduce carbon and waste, as part of Amgen's plan to be a carbon-neutral company by 2027. In addition to the base salary, Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including: Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
Specialist Manufacturing New Product Introduction (NPI):Downstream Readiness Amgen IncSpecialist Manufacturing New Product Introduction (NPI):Downstream ReadinessHolly Springs, NCIn addition to the base salary, Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including: Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. Responsibilities: New Product Introduction (NPI) lead coordinating with Manufacturing, Process Development, Supply Chain, Planning, Facilities and Engineering, Quality, and other teams to introduce new Drug Substance products and/or advanced technologies into the plant using project management tools.
Front Line Manufacturing Manager - Downstream Bulk Drug Substance - Days Amgen IncFront Line Manufacturing Manager - Downstream Bulk Drug Substance - DaysHolly Springs, NCIn addition to the base salary, Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including: Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. This essential role will lead a team responsible for manufacturing downstream purification operations including column packing, column chromatography, TFF, viral filtration, viral inactivation, conjugation, and final fill while partnering across functions to ensure successful operational readiness, technology transfer, and ramp‑up of manufacturing operations within the new facility.
Specialist - Metals and Critical Minerals McKinsey & Co IncSpecialist - Metals and Critical MineralsRaleigh, NCYou will develop and maintain a strong internal reputation and network with client teams, and will be "in the flow" of new external thinking to renew personal knowledge and expertise over time to remain at leading edge in the field. Undergraduate degree with excellent academic record required, ideally in metallurgical engineering, materials science, chemical engineering, mechanical engineering or a closely related field; advanced degree in similar field a plus.
Senior Manufacturing Systems Engineer: Automation (Swing Shift Monday - Friday) Amgen IncSenior Manufacturing Systems Engineer: Automation (Swing Shift Monday - Friday)Holly Springs, NCWhen completed, the Amgen FleX batch facility will combine the latest in disposable technologies with traditional stainless steel equipment to allow for maximum flexibility in operations The FleX Batch facility will not only feature the best in-class drug substance manufacturing technologies with embedded industry 4.0 capabilities, but it will also integrate sustainability innovations to reduce carbon and waste, as part of Amgen's plan to be a carbon-neutral company by 2027. Direct knowledge of Automation System design, experience in process control engineering and troubleshooting with GMP biopharmaceutical production facility equipment/systems automation such as media, harvest, bioreactors, solution prep, single use mixing vessels, chromatography, TFFL/TFFX, viral filtration, viral inactivation, UF/DF, depth filtration, drug substance fill, CIP/SIP, clean utilities, and integrating various OEM automation software.
Senior Manufacturing Systems Engineer: Automation (Wednesday - Saturday Shift) Amgen IncSenior Manufacturing Systems Engineer: Automation (Wednesday - Saturday Shift)Holly Springs, NCWhen completed, the Amgen FleX batch facility will combine the latest in disposable technologies with traditional stainless steel equipment to allow for maximum flexibility in operations The FleX Batch facility will not only feature the best in-class drug substance manufacturing technologies with embedded industry 4.0 capabilities, but it will also integrate sustainability innovations to reduce carbon and waste, as part of Amgen's plan to be a carbon-neutral company by 2027. Direct knowledge of Automation System design, experience in process control engineering and troubleshooting with GMP biopharmaceutical production facility equipment/systems automation such as media, harvest, bioreactors, solution prep, single use mixing vessels, chromatography, TFFL/TFFX, viral filtration, viral inactivation, UF/DF, depth filtration, drug substance fill, CIP/SIP, clean utilities, and integrating various OEM automation software.
Front Line Manufacturing Manager (Bulk Drug Substance - Downstream) - Day Shift Amgen IncFront Line Manufacturing Manager (Bulk Drug Substance - Downstream) - Day ShiftHolly Springs, NCIn addition to the base salary, Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including: Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. The FleX Batch facility not only features the best in-class drug substance manufacturing technologies with embedded industry 4.0 capabilities, but it also integrates sustainability innovations to reduce carbon and waste, as part of Amgen's plan to be a carbon-neutral company by 2027.
Senior Manager, Quality Control Kyowa Kirin Pharmaceutical Research IncSenior Manager, Quality ControlSanford, NCRemote$137,300–$185,000 / yearProvide technical leadership, collaborating cross-functionally in the site''s early-stage activities, including: facility detailed design review; facility, equipment, and analytical instrument user requirements review; prioritization for implementation of equipment, instruments, and analytical methods required for facility start-up (GMP Ready/OQ Complete); and ICT efforts for developing user requirements and procuring selected electronic Quality Systems for operations (LIMS/ELN/Empower). Summary of Job: The Senior Manager, Quality Control will play a critical role in designing, developing, and executing the operational readiness program for the start-up of the Quality Control laboratories at the new Kyowa Kirin North America monoclonal antibody drug substance manufacturing facility in Sanford, NC.
Manufacturing Systems Engineer: Automation (Swing Shift Monday - Friday) Amgen IncManufacturing Systems Engineer: Automation (Swing Shift Monday - Friday)Holly Springs, NCDirect knowledge of Automation System design, experience in process control engineering and troubleshooting with GMP biopharmaceutical production facility equipment/systems automation such as media, harvest, bioreactors, solution prep, single use mixing vessels, chromatography, TFFL/TFFX, viral filtration, viral inactivation, UF/DF, depth filtration, drug substance fill, CIP/SIP, clean utilities, and integrating various OEM automation software. As a member of the Amgen team, you'll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.
Front Line Manufacturing Manager (Bulk Drug Substance - Downstream) - Night Shift AmgenFront Line Manufacturing Manager (Bulk Drug Substance - Downstream) - Night ShiftHolly Springs, North CarolinaIn addition to the base salary, Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including: Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. The FleX Batch facility not only features the best in-class drug substance manufacturing technologies with embedded industry 4.0 capabilities, but it also integrates sustainability innovations to reduce carbon and waste, as part of Amgen's plan to be a carbon-neutral company by 2027.