Scientific Operations Manager / Associate Scientist, Oligonucleotide Synthesis & Analytical Sciences Alloy Therapeutics IncScientific Operations Manager / Associate Scientist, Oligonucleotide Synthesis & Analytical SciencesWaltham, MA$100,000–$125,000 / yearDesign and facilitate a tactical tier board system (Tier 1 through Tier 3) to drive daily accountability and structured escalation, tracking KPIs (on-time delivery and turnaround time by sequence class, synthesis first-pass success rate, average stepwise coupling efficiency, isolated yield, purity at release, resynthesis/rework rate, and OOS rate), action items, and resource constraints, and champion continuous improvement using lean principles. Own end-to-end demand planning for the NAC team-intake and triage of sequence requests (oligonucleotide length, chemistry, modification pattern, scale and conjugation), capacity forecasting against synthesizer column and plate availability, batch scheduling, and queue prioritization with input from biology, program management, and leadership-and provide real-time status visibility on every sequence from request through release via dashboards and reporting.
Scientist, Gene Editing Sciences & Laboratory Operations MaxCyteScientist, Gene Editing Sciences & Laboratory OperationsWaltham, MAAbout the Role: MaxCyte's SeQure platform applies state-of-the-art genomics technologies for CRISPR gene editing target profiling to advance discovery, clinical development, and diagnostic solutions. This individual will play a key role in evaluating emerging genome engineering technologies, implementing new workflows, supporting client studies, and driving continuous process improvement.
Principal Scientist, Translational Data Science Parabilis MedicinesPrincipal Scientist, Translational Data ScienceCambridge, MA$215,000–$245,000 / yearFor Programs, you will work in support of the Program Lead Data Scientist, collaborating with translational scientists, clinicians, biostatisticians, biomarker scientists, pathology, RWD/E colleagues, and other functions to connect emerging development and clinical observations with the underlying biology and preclinical evidence. Main tasks & duties for the position: Lead computational analyses supporting target identification and credentialing using tumor genomics, transcriptomics, functional genomics, human genetics, single-cell/spatial data, and relevant clinical and epidemiological datasets.
Senior Scientist - Translational Safety & Risk Sciences (TSRS) Amgen IncSenior Scientist - Translational Safety & Risk Sciences (TSRS)Cambridge, MAIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients.
Senior Scientist - Translational Safety & Risk Sciences (Tsrs) Amgen Inc.Senior Scientist - Translational Safety & Risk Sciences (Tsrs)Cambridge, MAIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients.
Sr. Principal Scientist / Director, DMPK & Bioanalytical Sciences Flagship Pioneering IncSr. Principal Scientist / Director, DMPK & Bioanalytical SciencesCambridge, MA$179,000–$236,000 / yearThe company's initial therapeutic programs are designed to restore full-length protein production in diseases caused by premature termination codons (PTCs), collectively referred to as Stop Codon Disease, which affects approximately 10% of people with a rare genetic disease. Reporting to the Chief Scientific Officer, this role leads DMPK and bioanalytical strategy across nonclinical and clinical programs, operating as a hands-on scientific leader.
Pioneering Medicines: Scientist / Sr. Scientist, Translational Sciences T-cell focused Flagship Pioneering IncPioneering Medicines: Scientist / Sr. Scientist, Translational Sciences T-cell focusedCambridge, MA$100,000–$181,500 / yearFlagship has been recognized twice on FORTUNE's "Change the World" list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company's annual list of the World's Most Innovative Companies. Harnessing the drug development expertise of its team together with the power of Flagship''s multiple scientific platforms, Pioneering Medicines explores and identifies new product concepts which are then advanced jointly with Flagship's bioplatform companies.
NewPioneering Medicines: Scientist / Sr. Scientist, Translational Sciences (T-cell focused) Flagship Pioneering, Inc.Pioneering Medicines: Scientist / Sr. Scientist, Translational Sciences (T-cell focused)Cambridge, MA USA$100,000–$181,500 / yearFlagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Harnessing the drug development expertise of its team together with the power of Flagship's multiple scientific platforms, Pioneering Medicines explores and identifies new product concepts which are then advanced jointly with Flagship’s bioplatform companies.
NewSr. Principal Scientist / Director, DMPK & Bioanalytical Sciences Flagship Pioneering, Inc.Sr. Principal Scientist / Director, DMPK & Bioanalytical SciencesCambridge, MA USA$179,000–$236,000 / yearThe company’s initial therapeutic programs are designed to restore full-length protein production in diseases caused by premature termination codons (PTCs), collectively referred to as Stop Codon Disease, which affects approximately 10% of people with a rare genetic disease. Reporting to the Chief Scientific Officer, this role leads DMPK and bioanalytical strategy across nonclinical and clinical programs, operating as a hands-on scientific leader.
Data Scientist II / Senior Data Scientist, Life Sciences Lila SciencesData Scientist II / Senior Data Scientist, Life SciencesCambridge, MassachusettsFull-time U.S. employees receive a comprehensive benefits program including medical, dental, and vision coverage; employer-paid life and disability insurance; flexible time off with generous company wide holidays; paid parental leave; an educational assistance program; commuter benefits, including bike share memberships for office based employees; and a company subsidized lunch program. This person will turn experimental data into actionable scientific insight, translate bench workflows into validated analytical requirements, and build reproducible analysis patterns that scale across life sciences programs.
Sr. Scientist, Delivery Sciences Moderna IncSr. Scientist, Delivery SciencesCambridge, MA$130,800–$209,400 / yearWe are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S. If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities. In this role, you will advance the science of LNP self-assembly, engineer delivery systems for small- and large-molecule payloads beyond the liver and leverage state-of-the-art analytical techniques to establish structure-function relationships that drive biological performance.
Principal Scientist, Translational Modeling & Decision Science Flagship Pioneering IncPrincipal Scientist, Translational Modeling & Decision ScienceCambridge, MA$179,000–$236,000 / yearFlagship has been recognized twice on FORTUNE's "Change the World" list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company's annual list of the World's Most Innovative Companies. PhD in a life sciences discipline with quantitative experience, or in a quantitative life sciences discipline (pharmacometrics, systems pharmacology, computational biology, biomedical engineering, or equivalent) with strong knowledge of physiology, molecular biology, and immunology.
NewSenior / Principal Scientist - Translational Modeling & Decision Science Flagship Pioneering, Inc.Senior / Principal Scientist - Translational Modeling & Decision ScienceCambridge, MA USA$146,000–$236,000 / yearTh is forward-deployed role bridges the gap from capability to impact by leveraging PI technologies to tak e on tr anslation al challenges across Flagship’s therapeutic portfolio , delivering value through programs and business decisions while returning insights that improve the AI platform. . PhD in a life sciences discipline with quantitative experience, or in a quantitative life sciences discipline (pharmacometrics, systems pharmacology, computational biology, biomedical engineering, or equivalent) with 3 to 7 years of industry experience with strong knowledge of physiology, molecular biology, and immunology .
Principal Scientist / Associate Director, Agentic AI Research for Materials Science Lila Sciences IncPrincipal Scientist / Associate Director, Agentic AI Research for Materials ScienceCambridge, MA$288,000–$420,000 / yearFull-time U.S. employees receive a comprehensive benefits program including medical, dental, and vision coverage; employer-paid life and disability insurance; flexible time off with generous company wide holidays; paid parental leave; an educational assistance program; commuter benefits, including bike share memberships for office based employees; and a company subsidized lunch program. LILA combines advanced AI models with proprietary AI Science Factory instruments into an operating system for science that executes the entire scientific method autonomously, accelerating discovery at unprecedented speed, scale, and impact across medicine, materials, and energy.
NewAssociate Director, Data Science, Computational Oncology Merck & Co IncAssociate Director, Data Science, Computational OncologyBoston, MA$159,600–$251,200 / yearA PhD in computational biology, bioinformatics, biostatistics, genetics/genomics, computational biology, mathematics, computer science, biophysics, computational chemistry or a related quantitative STEM discipline and 4+ years of relevant experience; MS and 8+ years of relevant experience; OR BS and 12+ years of relevant experience. Analyze large-scale oncology datasets, including bulk RNA-seq, whole-exome and whole-genome sequencing (WES/WGS), and single-cell RNA-seq (scRNA-seq), to understand disease biology and the mechanisms of disease progression and drug action.
Head of Translational Sciences, Drug Design, Cambridge, MA Isomorphic Labs LimitedHead of Translational Sciences, Drug Design, Cambridge, MACambridge, MAThis team will be highly collaborative and need to establish strong scientific relationships with multiple groups in the company, from Medicinal Chemists to Applied Machine Learning Scientists, creating a powerful symbiotic relationship that drives our internal and collaborative portfolios. Direct all in vitro and in vivo biology operations in Cambridge, MA through a network of CROs to generate, ingest and interpret high quality experimental data efficiently to support all aspects of our drug design programs from HitID through to IND.
Sr. Manager, Data Science & Analytics Nova BiomedicalSr. Manager, Data Science & AnalyticsWaltham, MA$210,000–$250,000 / yearDriven by innovation and guided by our core values — Customer Centricity, Ingenuity, Ownership & Accountability, Collaboration, and Integrity — Nova creates solutions that make a global impact. By combining our strengths, we are accelerating innovation, supporting critical workflows, and delivering world-class service across the biopharmaceutical and clinical markets.
Scientist II, Data Science Les Laboratoires Servier SASScientist II, Data ScienceBoston, MA$146,000–$165,000 / yearAs a privately held organization, Servier is uniquely positioned to advance cutting-edge science, tackle underserved therapeutic areas, and make patients the focus of every strategic decision. An employee's pay position within the salary range will be based on several factors including, but not limited to, relevant education, qualifications, certifications, experience, skills, geographic location, performance, and business or organizational needs.
Assistant/Associate Professor of Biostatistics and Data Science Harvard UniversityAssistant/Associate Professor of Biostatistics and Data ScienceCambridge, MA$154,000–$180,000 / yearChan School of Public Health (HSPH) seek candidates to fill a tenure-track faculty position at the Assistant or Associate Professor level in the field of statistics or machine learning, with demonstrated interest in single-cell or spatial genomics applications. Chan School of Public Health and Data Science at the Dana-Farber Cancer Institute provide exceptional environments to pursue research and education in quantitative methods, while leading global efforts to improve the health of individuals and populations.
Principal Scientist I or II, PK Sciences Therapeutic Areas (Multiple Listings) Novartis AGPrincipal Scientist I or II, PK Sciences Therapeutic Areas (Multiple Listings)Cambridge, MA$108,500–$201,500 / yearA minimum of 0-2 years of experience in drug discovery and/or development in a relevant environment (academia, CRO, biotech or Pharma).• 2+ years of experience preferably in a lead role overseeing ADME/DMPK project strategy, either in discovery or clinical development to be considered for Principal Scientist II• Extensive and in-depth knowledge of pharmacokinetics including, drug metabolism and PK/PD evaluation, experience in working in project teams (preferably global) as well as sound awareness of recent developments in drug development and regulatory sciences.• • Works in close collaboration with clinicians and clinical development colleagues to integrate PKS insights into study design, data interpretation, and project decision‑making• Use of Artificial intelligence (AI) / Machine Learning (ML) approaches to enable model guided molecular design, preclinical and clinical data automation, authoring regulatory documents, and the use of predictive modelsThis role reports to Therapeutic Area group in PK Sciences within Translational Medicine (TM) in Biomedical Research.