Working with a high degree of independence under the guidance of a senior scientific lead, the successful candidate will plan, execute, and interpret in vivo studies - alongside supporting ex vivo and in vitro assays - to identify and validate novel druggable oncology targets, and advance targets from the pre-DC pipeline into the Astellas drug portfolio. including tail-vein injection), tumor cell implantation (subcutaneous, orthotopic, and intravenous), tumor caliper measurements, body weight and body condition scoring, blood and terminal sample collection, and rodent survival surgeries for in vivo efficacy, PK/PD, safety and mechanistic studies in relevant mouse models.