Principal Automation Engineer 3383 Shire Human Genetic TherapiesPrincipal Automation EngineerLexington, MassachusettsAny individual may provide documentary evidence bearing on this application, with information on available workers and information on wages and working conditions, to the Certifying Officer, U.S. Department of Labor, Employment and Training Administration, Office of Foreign Labor Certification, 200 Constitution Avenue, NW, Room N-5311, Washington, DC 20210. POSITION DESCRIPTION : Shire Human Genetic Therapies, Inc. is seeking a Principal Automation Engineer with the following duties: responsible for operational, project, and strategic support of PLC, DCS, Manufacturing Execution systems, and ancillary data systems used to control and collect data for various building and manufacturing unit operations.
Principal Test Engineer - Product Development Analog DevicesPrincipal Test Engineer - Product DevelopmentWilmington, MassachusettsADI combines analog, digital, AI, and software technologies into solutions that combat climate change, reliably connect humans and the world, and help drive advancements in automation and robotics, mobility, healthcare, energy and data centers. For positions requiring access to technical data, Analog Devices, Inc. may have to obtain export licensing approval from the U.S. Department of Commerce - Bureau of Industry and Security and/or the U.S. Department of State - Directorate of Defense Trade Controls.
Tax Principal - Life Sciences Baker Tilly Virchow Krause, LLPTax Principal - Life SciencesTewksbury, MAWhat you will do: Be a trusted leader of Baker Tilly's tax services, providing federal tax compliance and consulting services to commercial clients, positively impacting your clients through: Being a valued tax business advisor, leading client relationships on day-to-day tax matters with various clients ranging from middle market to multinational. Baker Tilly Advisory Group, LP and Baker Tilly US, LLP, trading as Baker Tilly, are independent members of Baker Tilly International, a worldwide network of independent accounting and business advisory firms in 141 territories, with 43,000 professionals and a combined worldwide revenue of $5.2 billion.
Principal Engineer, Systems Design/Architecture Engineering Analog DevicesPrincipal Engineer, Systems Design/Architecture EngineeringWilmington, MassachusettsADI combines analog, digital, AI, and software technologies into solutions that combat climate change, reliably connect humans and the world, and help drive advancements in automation and robotics, mobility, healthcare, energy and data centers. For positions requiring access to technical data, Analog Devices, Inc. may have to obtain export licensing approval from the U.S. Department of Commerce - Bureau of Industry and Security and/or the U.S. Department of State - Directorate of Defense Trade Controls.
Principal Security Operations Engineer AxonPrincipal Security Operations EngineerBoston, MA$168,750–$270,000 / yearExpert-level Kubernetes experience, with deep hands-on knowledge of cluster architecture, provisioning, upgrades, networking, RBAC, policy enforcement, workload security, and operating production Kubernetes environments at scale. Lead architectural reviews and improvements across Axon's Kubernetes platforms, identifying security, reliability, and operational gaps and partnering with platform teams to implement scalable solutions.
Principal Product Technical Leader PfizerPrincipal Product Technical LeaderAndover, MA$124,400–$207,400 / yearThis role is accountable for establishing, maintaining, and continuously improving site-level product technical strategies and product lifecycle management, ensuring site‑ and network‑aligned control strategies, validated‑state compliance, effective risk management, and sustained technical excellence. As a Principal Product Technical Leader in Site Technical Services, you will serve as the technical product portfolio owner, setting product philosophy and strategy while acting as the site point of contact within network governance and cross‑functional project teams.
Associate Principal Analyst, Surveillance And Market Intelligence Financial Industry Regulatory Authority, Inc.Associate Principal Analyst, Surveillance And Market IntelligenceBoston, MAFINRA employees are required to disclose to FINRA all brokerage accounts that they maintain, and those in which they control trading or have a financial interest (including any trust account of which they are a trustee or beneficiary and all accounts of a spouse, domestic partner or minor child who lives with the employee) and to authorize their broker-dealers to provide FINRA with duplicate statements for all of those accounts. Additional insurance includes basic life, accidental death and dismemberment, supplemental life, spouse/domestic partner and dependent life, and spouse/domestic partner and dependent accidental death and dismemberment, short- and long-term disability, long-term care, business travel accident, disability and legal.
Principal Embedded Software Test Engineer MondoPrincipal Embedded Software Test EngineerDanvers, Massachusetts$115,000–$197,800 / yearLeads embedded software testing strategy and execution for complex, regulated products, ensuring quality across multiple full development lifecycles. Guide testing strategy for device communication protocols and board-level validation.
Principal Software Engineer eClinical SolutionsPrincipal Software EngineerMansfield, Massachusetts$152,000–$190,000 / yeareClinical Solutions is transforming clinical development with elluminate®, our Clinical Data Cloud , helping life sciences organizations unify, analyze, and unlock the value of their data faster than ever before. This role is ideal for an experienced engineer who enjoys hands-on development , mentoring others, and bringing modern capabilities—including AI-assisted and agentic workflows—into production-grade systems .
Principal Cloud Kubernetes Engineer InterSystemsPrincipal Cloud Kubernetes EngineerBoston, MassachusettsWe are seeking a Principal Cloud Kubernetes Engineer to join our global infrastructure team to lead the architecture, strategy, and evolution of our cloud-native platform across public cloud and on-premises environments. Our data platforms solve interoperability, speed, and scalability problems for large organizations around the globe to unlock the power of data and allow people to perceive data in imaginative ways.
Principal Optical Engineer QuEra ComputingPrincipal Optical EngineerBoston, Massachusetts$151,200–$236,250 / yearThe Hardware Engineering Group at QuEra Computing is seeking strong candidates for a Principal Optical Engineer to serve as a senior individual contributor to the company’s mission of building state-of-the-art, manufacturable, and deployable neutral atom quantum computers. Work with physicists to understand requirements and architect optical systems, sub-systems, modules, and components to support QuEra’s neutral atom computers through the full development lifecycle (R&D, productization, maintenance, and beyond).
Principal Integration Engineer MaximusPrincipal Integration EngineerBoston, MAFull timeDrive adoption of modern integration patterns, including API-first design, event-driven architectures, microservices-aligned integrations, and reusable integration components. • Proven experience designing scalable enterprise integration architectures across cloud services, SaaS platforms, enterprise applications and APIs.
Principal Analyst, Sales Operations Strategic Initiatives Analog DevicesPrincipal Analyst, Sales Operations Strategic InitiativesWilmington, MassachusettsAnalog Devices (ADI) is seeking a highly strategic and commercially minded Principal Analyst, Sales Operations Strategic Initiatives to drive the successful implementation, adoption, measurement, and continuous improvement of critical commercial initiatives across the global sales organization. This role serves as the operational bridge between Sales Leadership, Business Unit Leadership, and Sales Operations, ensuring strategic initiatives are clearly defined, consistently executed, and embedded into day-to-day sales processes.
NewPrincipal Systems Architect, Communications Hardware (Remote Eligible | Relocation Assistance Available) AxonPrincipal Systems Architect, Communications Hardware (Remote Eligible | Relocation Assistance Available)Boston, MARemote$210,600–$242,100 / yearYou will partner closely with Electrical Engineering (EE), Radio Frequency (RF) Engineering, Software (SW) Engineering, and Mechanical Engineering (ME) leads to define system requirements, drive cross-functional design decisions, and ensure each subsystem comes together as a cohesive, production-ready device. Familiarity with relevant hardware design, simulation, testing, and lifecycle tools , such as Altium/Cadence, SolidWorks/Creo/NX, RF and electrical test equipment, thermal characterization tools, and PLM/BOM or requirements-management systems.
Risk Advisory Services Principal Baker Tilly Virchow Krause, LLPRisk Advisory Services PrincipalTewksbury, MAWork closely with client executives and management teams to understand their businesses and assist in identifying and managing financial and operational risks within their business systems to ensure technology risks are managed: Develop in-depth knowledge of clients' businesses and industries by having direct client interaction while working on multiple aspects of an engagement. Baker Tilly Advisory Group, LP and Baker Tilly US, LLP, trading as Baker Tilly, are independent members of Baker Tilly International, a worldwide network of independent accounting and business advisory firms in 141 territories, with 43,000 professionals and a combined worldwide revenue of $5.2 billion.
Principal Customer Solutions Architect, Ads Regulatory Compliance MicrosoftPrincipal Customer Solutions Architect, Ads Regulatory ComplianceBoston, MA$142,800–$274,800 / yearAs the Principal Customer Solutions Architect, Ads Regulatory Compliance, you will operate at the intersection of product, engineering, policy, legal, operations, and business strategy to translate emerging regulatory requirements into scalable frameworks, governance models, and solution architectures. There is a different range applicable to specific work locations, within the San Francisco Bay area and New York City metropolitan area, and the base pay range for this role in those locations is USD $188,000 - $304,200 per year.
Principal Manufacturing Engineer-Npi TransMedics Group, Inc.Principal Manufacturing Engineer-NpiAndover, MA$147,200–$183,600 / yearJob Description: POSITION SUMMARY: The Principal Engineer - NPI Manufacturing serve as the technical project leader for NPI manufacturing activities, driving the development and commercialization of TransMedics perfusion set and OCS products. To accomplish this mission, we partner closely with transplant stakeholders worldwide and help expand their access to healthy donor organs, while delivering the highest quality technology, service, clinical care and outcomes.
Principal Mechanical Engineer, Process Equipment Boston Materials, IncPrincipal Mechanical Engineer, Process EquipmentBillerica, MA$160,000–$190,000 / yearDesign and requisition mechanical machinery and components using CAD (SolidWorks preferred), ensuring design specifications are met, and manage design files, revisions, and workflows within a Product Data Management (PDM) system. 8+ years designing, building, and commissioning custom capital equipment in advanced materials, semiconductor packaging, battery, display, web converting, or other environments where the fidelity of a chemical or materials process must be preserved by the equipment design.
Principal Consultant - Life Sciences LumanityPrincipal Consultant - Life SciencesBoston, MassachusettsAs a trusted advisor to senior leaders across the life sciences industry, you will lead complex consulting engagements, cultivate long-term client relationships, identify new business opportunities, and mentor high-performing consulting teams. As a global strategic partner that brings together strategy, evidence, engagement, and technology, we were designed to engineer breakthrough value to tackle our clients’ toughest challenges by revolutionizing how value is generated, demonstrated, and communicated.
Principal Analyst - Enterprise CX Transformation Forrester Research, Inc.Principal Analyst - Enterprise CX TransformationCambridge, MA$141,000–$229,000 / yearYou'll conduct visionary original research that helps senior CX executives across industries build the experiences and CX programs of the future - and you'll advise these leaders on how to customize and implement your findings. In this role, you'll examine how senior CX leaders build and operate cutting-edge CX programs and drive enterprisewide customer-led innovation amid the rise of AI and volatility.