QA Specialist IV Integrated Resources, IncQA Specialist IVLexington, MassachusettsFull timeResponsibilities-This position is responsible for monitoring and supporting batch disposition of bulk drug products (DP) and finished drug products (FDP)The individual may be responsible for, but is not limited to: Conducting record review of executed batch records for finish drug products to support CMO packaging & labeling record reviewPerforming review of bulk drug product executed records, if neededPrepares all paper work for product disposition (bulk and finished product) and performed assessments for impact to disposition from deviations and change controlsReviews and approve deviations and change controls related to DP and FDPMay own CAPAs associated within the QA unitSupports drug product and finish drug product annual review report sectionsUnderstanding of GMP'sSupports departmental projects as neededQualificationsBachelor's degree in chemistry, biology or a related discipline6-8 years Quality Assurance experience supporting the manufacture and/or release of drugs, biologics, or devices at CMOsWorking knowledge of DP and FDP batch record reviewUnderstanding of quality systems and cGMPs. Interpersonal skills and professional skills to interact with customersMust be flexibleMust be able to prioritize and multitask in a stressful environmentFluency in English is requiredSignificant experience in parenteral biotech manufacturing (aseptic or sterile processing)Significant experience working with suppliers and/or contract manufacturing organizationsExperience with TrackWise and LIMS systemsExperience with packaging and labeling operationsEvaluation of batches to ensure completeness, accuracy and complianceEvaluation of manufacturing or operational issues for impact and communication to management.
Stability Coordinator II Integrated Resources, IncStability Coordinator IILexington, MassachusettsFull timeThe Stability Coordinator will initiate stability studies for drug substance and drug product, maintain stability equipment, perform stability pulls, coordinate sample preparation/submission and testing, publish a monthly stability pull/testing status dashboard, follow through for on-schedule data delivery, receive, summarize and archive stability data, and manage stability inventory. Job DescriptionThe Stability Coordinator will be responsible for managing development stability studies including study execution and data management in alignment with regulatory guidance documents (CFR, ICH, etc.).In this role, the Stability Coordinator will interact with and support multiple cross-functional teams to meet stability needs for clinical programs in all stages of development.
NewQuality Control Scientist II BelcanQuality Control Scientist IIWestborough, MAThis role provides technical leadership across QC Microbiology and Manufacturing by ensuring effective microbiological testing, mentoring laboratory staff, supporting quality systems and delivering aseptic technique training to maintain compliance with GMP and contamination control requirements. Description The Scientist II QC Microbiology serves as senior technical subject matter expert responsible for overseeing microbiological testing programs supporting GMP operations.
Manager Regulatory Affairs-CMC Integrated Resources, IncManager Regulatory Affairs-CMCLexington, MassachusettsContractorJob DescriptionJob Title: Manager Regulatory Affairs-CMCLocation: Lexington, MA Duration: 4+months (Possibility of extension) Business Function: R&D Department Name: Global Regulatory Affairs Primary Role:Under the general direction of the CMC Regulatory Affairs team, develop a Core Dossier for Module 2.3 and Module 3 CTD sections for a marketed product, and leverage the Core Dossier documents to support Marketing Authorization Applications for international regions. Responsibilities:50% of the time develops global CMC Core Dossier for Module 2.3 and Module 3 CTD sections50% of the time prepares CMC components of new Marketing Authorization Applications for international countriesEDUCATION & EXPERIENCE Requirements:Bachelor's degree in pharmacy, biochemistry, chemistry, biology or related pharmaceutical field.
Staff Forward Deployed Engineer, Life Sciences Lila SciencesStaff Forward Deployed Engineer, Life SciencesCambridge, Massachusetts$192,000–$256,000 / yearFull-time U.S. employees receive a comprehensive benefits program including medical, dental, and vision coverage; employer-paid life and disability insurance; flexible time off with generous company wide holidays; paid parental leave; an educational assistance program; commuter benefits, including bike share memberships for office based employees; and a company subsidized lunch program. LILA combines advanced AI models with proprietary AI Science Factory instruments into an operating system for science that executes the entire scientific method autonomously, accelerating discovery at unprecedented speed, scale, and impact across medicine, materials, and energy.
Global Regulatory Affairs (CMC) Manager Integrated Resources, IncGlobal Regulatory Affairs (CMC) ManagerLexington, MassachusettsContractorJob DescriptionClient: Direct ClientLocation: Lexington, MAJob Title: Global Regulatory Affairs (CMC) ManagerDuration: 5 Months + (Possible Extension)Summary: Under the direction of the Director of Regulatory Affairs direct and manage Regulatory Affairs activities for developing global CMC strategies across product life cycles & execution in North America. Job Function and Description:• Provide regulatory support, guidance and expertise to internal groups such as product development, QA, QC and manufacturing teams to ensure that all applicable regulatory requirements are considered and appropriately incorporated into development programs and that products are developed and manufactured in compliance with appropriate regulations and guidelines so that they be studied and marketed as planned.•
Medical Laboratory Scientist AptiveMedical Laboratory ScientistWest Roxbury, Massachusetts$40–$45 / hourFull timeThe employee will perform routine chemistry and urinalysis testing using automated instrumentation, including Beckman Coulter Urinalysis systems, Advanced Instruments Osmos, Polymedco OC80, and manual urinalysis and chemistry methods. The employee will perform routine chemistry testing using automated instrumentation, including Abbott Architect ci8200, Abbott Alinity, Advanced Instruments Osmos, Polymedco OC80, and manual chemistry methods.
NewResearch Associate Drug Product Development Astellas Pharma IncResearch Associate Drug Product DevelopmentWestborough, MAContributes to drug product process development and technical transfer activities through cell culture, formulation screening and product characterization studies. The Research Associate II will support drug product development activities including formulation screening, process development and optimization, in-use evaluation, analyzing data.
(Sr.) Principal Scientist Molecular Cell Biologist (Sr.) Principal Scientist Molecular Cell Biologist Saviance Technologies(Sr.) Principal Scientist Molecular Cell Biologist (Sr.) Principal Scientist Molecular Cell BiologistBoston, MAExperience in molecular endpoints, including, PCR, qPCR, ddPCR, and protein analysis (Simple Western Jess, ELISA, MSD, Octet). Perform cell culture and molecular biology experiments and establish new functional assays to measure gene therapy outcomes both in vitro and in vivo.
Process Development Research Scientist Brigham and Women's HospitalProcess Development Research ScientistBoston, MA$60,000–$96,000 / yearThe Process Development Laboratory is a highly integrated, innovation-driven facility dedicated to translating next-generation cellular immunotherapy and gene engineering technologies into clinically deployable manufacturing solutions. The successful candidate will contribute to the design, development, optimization, and clinical translation of novel manufacturing workflows poised for IND-enabling studies and early-phase clinical trials, while operating in a collaborative academic medical center environment.
Research Fellow, PGY 4 Brigham and Women's HospitalResearch Fellow, PGY 4Boston, MA$70,000–$71,750 / yearPOSITION SUMMARY: The Chekuri Lab is seeking a postdoctoral fellow to join an NIH-funded research program focused on understanding the molecular mechanisms of inherited retinal degenerative diseases and developing genetic therapies for these conditions. The postdoctoral fellow will lead a mentored research project involving in vitro and in vivo experiments, molecular and functional outcome analyses, data presentation, manuscript preparation, and collaborative project development.
NewSenior Scientist, Translational Computational Biology Bristol-Myers Squibb CoSenior Scientist, Translational Computational BiologyMA$148,210–$179,601 / yearSpatial biology: hands-on experience with spatial transcriptomics (e.g., Visium, Xenium, CosMx, GeoMx, MERFISH) and/or spatial proteomics and multiplex immunofluorescence (e.g., Lunaphore COMET, RareCyte Orion, Akoya), including cell segmentation, phenotyping, and neighborhood or spatial statistics; familiarity with the analysis stack (Squidpy, SpatialData, scverse) and with digital pathology tooling (HALO, QuPath). What you will have to work with: Clinical and multi-modal patient-derived datasets from BMS's industry-leading early-stage clinical studies in oncology: the molecular and clinical biomarker data generated by our own early-phase trials, spanning RNA-seq, WES, TCR-seq, ctDNA and CTC, together with flow cytometry, cytokine profiling, IHC, and proteomics.
Senior Scientist, AI Computational Structural Biology Bristol-Myers Squibb CoSenior Scientist, AI Computational Structural BiologyMA$148,210–$179,601 / yearRequirements - Technical Skills & Experience: AI/ML & Deep Learning: Proven experience developing and deploying AI/ML models in biological or biochemical contexts, with proficiency in deep learning architectures for structural data (GNNs, equivariant neural networks, transformers, diffusion, flow matching) using Python and relevant libraries (PyTorch, JAX, RDKit, ESM/fair-esm, Biopython, etc.). IPS conducts applied computational research in areas that include genomic, structural and molecular informatics, computational and systems biology, patient selection and translational biomarker research, and broader fields including knowledge science, epidemiology and machine learning-across the full lifecycle of drug discovery and development and across all therapeutic areas at BMS.
Principal Scientist, Computational Biology Bristol-Myers Squibb CoPrincipal Scientist, Computational BiologyMARemote$166,770–$202,086 / yearIPS conducts applied computational research in areas that include genomic, structural and molecular informatics, computational and systems biology, patient selection and translational biomarker research, and broader fields including knowledge science, epidemiology and machine learning-across the full lifecycle of drug discovery and development and across all therapeutic areas at BMS. Hands on experience analyzing and integrating high-dimensional molecular datasets such as multi-omics (RNA-seq, ATAC-seq, proteomics, ChIP-seq/CUT&RUN), single cell profiling (CITE-seq, scATAC-seq, perturb-seq) and/or spatial profiling to derive novel biological insights.
NewPostdoctoral Scientist - Neuroscience (Synuclein Biology) Eli Lilly and CoPostdoctoral Scientist - Neuroscience (Synuclein Biology)Boston, MA$58,000–$123,200 / yearOur current groups include: Africa, Middle East, Central Asia (AMECA), Black Employees at Lilly (BE@Lilly), Chinese Culture Network (CCN), EnAble, Evolve, Lilly Indian Network (LIN), Organization of Latinx at Lilly (OLA), Pride (LGBTQ+ Allies), Veterans Leadership Network (VLN) and Women's Initiative for Leading at Lilly (WILL). The team brings together expertise in -synuclein biology, iPSC-derived neuronal models, high-content imaging, and target validation, with active efforts spanning small molecule discovery, gene therapy, and biomarker development.
NewPostdoctoral Scientist – Neuroscience (Synuclein Biology) Eli Lilly and CompanyPostdoctoral Scientist – Neuroscience (Synuclein Biology)MassachusettsOur current groups include: Africa, Middle East, Central Asia (AMECA), Black Employees at Lilly (BE@Lilly), Chinese Culture Network (CCN), EnAble, Evolve, Lilly Indian Network (LIN), Organization of Latinx at Lilly (OLA), Pride (LGBTQ+ Allies), Veterans Leadership Network (VLN) and Women’s Initiative for Leading at Lilly (WILL). The team brings together expertise in -synuclein biology, iPSC-derived neuronal models, high-content imaging, and target validation, with active efforts spanning small molecule discovery, gene therapy, and biomarker development.
Adjunct Faculty: Biology Bunker Hill Community CollegeAdjunct Faculty: BiologyBoston, MACourses offered in biology include: BIO 105 Introduction to Biology BIO 108 Human Biology/Lab BIO 115 Nutrition BIO 203 Anatomy/Physiology I/Lab BIO 204 Anatomy/Physiology II/Lab BIO 205 Microbiology/Lab. The Biology and Chemistry department offers biology courses that support majors in Biology, Biomedical Engineering, Medical Laboratory Technician, and Allied Health.
Senior Associate Scientist, In Vivo Pharmacology, Oncology Discovery Biology Bristol-Myers Squibb CoSenior Associate Scientist, In Vivo Pharmacology, Oncology Discovery BiologyMA$105,040–$127,287 / yearPosition Responsibilities: In the role as a Senior Associate Scientist within In Vivo Discovery Oncology, the ideal candidate will: Experience in conducting mouse in vivo pharmacology experiments, including but not limited to model development, tumor implantation, dosing via IV, IP, SC, IT, IM, and PO routes, tumor measurements, health monitoring, tissue sampling by tail vessel micro-sampling, cardiac puncture and tissue/tumor collection at necropsy including fixation, freezing and tissue disaggregation to support ex vivo analyses. Independently execute end-to-end flow cytometry workflows, encompassing panel design and establishment, multiparametric profiling of blood, tumor, and lymphoid tissues, downstream data analysis, and clear communication of results to cross-functional teams.
Senior Principal Scientist - Translational Muscle Biology UCBSenior Principal Scientist - Translational Muscle BiologyCambridge, MAThe candidate will bring hands-on scientific leadership to a matrixed team focused on identifying and building knowledge across pathobiological pathways and patient populations, including neuromuscular diseases related to nucleotide repeat expansions, genetic mutations, muscle atrophy, mitochondrial/lysosomal dysfunction, or inflammation. This is an opportunity for a scientific leader to advance portfolio projects and lead from the bench-exploring new biology and directly shaping the design, development, and execution of in vitro and in vivo models as well as cellular and biochemical assays for early drug discovery across multiple therapeutic programs and target discovery efforts.
Scientist, Cellular & Molecular Biology - Lexington, MA DSM Nutritional Products Asia Pacific Pte LtdScientist, Cellular & Molecular Biology - Lexington, MALexington, MA$100,000–$125,000 / yearThe successful candidate will play a hands-on role in designing and executing cell-based assays, supporting preclinical and translational studies, and handling human clinical samples in a BSL 2 laboratory environment. Collaborate closely with cross-functional teams (Data Science, Regulatory Affairs, and Biotechnology) to integrate cellular data into broader study frameworks.