Principal Scientist, DMPK Merck & Co IncPrincipal Scientist, DMPKBoston, MA$176,200–$277,300 / yearRequired Skills: ADME, Bioanalytical Method Development, Biologics, Cross-Functional Teamwork, DMPK, Drug Metabolism, Immunoassays, Immunology, In Vitro Studies, Mentoring Staff, Oncology, Peptides, Pharmaceutical Sciences, Pharmacodynamics, Pharmacokinetics, Pharmacotherapeutics, PKPD Modeling. The ideal candidate will lead drug metabolism and pharmacokinetic (DMPK) efforts across multiple modalities such as peptides and protein therapeutics as a project-team representative, regularly interacting with multi-disciplinary discovery teams and partners from other functions within our Research & Development Division.
Undergraduate Internship - Immune Organ on Chip Harvard UniversityUndergraduate Internship - Immune Organ on ChipMA$20–$25 / hourTrain with the immune organs-on-chip team to isolate human immune cells, human and mouse cancer cells and collaborate with them to set up different types of cocultures. What you'll Need: Background in cell biology, biomedical engineering, or related fields is required with some experience involving aseptic cell culture and endpoint assay analysis (ELISA, qPCR, Western, or imaging).
Senior Director MMAI & Outcome Prediction - AI for Precision Health AstraZeneca PlcSenior Director MMAI & Outcome Prediction - AI for Precision HealthBoston, MA$212.99–$319.49Working in close collaboration with Enterprise AI, R&D teams, and AI for Science Innovation (AISI), you will drive the development, reinforcement, and validation of multimodal predictive and diagnostic systems integrating radiology, digital pathology, multi-omics (genomics, transcriptomics, proteomics), molecular diagnostics, clinical trial datasets, real-world electronic health records and claims, and longitudinal patient signals including digital biomarkers. Advance multimodal biomarker and computational diagnostic strategies that integrate radiology, digital pathology, omics data, and digital biomarkers to refine disease taxonomy, identify biologically meaningful subtypes, and support precision medicine approaches including companion diagnostics and AI-enabled diagnostic tools.
Associate Director, Translational PK/PD Merck & Co IncAssociate Director, Translational PK/PDBoston, MA$156,900–$247,000 / yearThe Translational PK/PD Scientific Associate Director will: Serve as expert PK/PD modeler in cross-functional teams, to make model-informed decisions about drug discovery, modality selection, and dose prediction across therapeutic areas; Integrate in vitro and in vivo data to build PKPD, PBPK, quantitative systems pharmacology (QSP), or other mechanistic modeling platforms of drug disposition and pharmacology, to support forward/reverse translation for both established and novel therapeutic targets; Collaborate across our PDMB and broader Discovery / Translational organization to design experimental studies and modeling plans, to identify and optimize drug candidates and guide broader translational strategy across programs; Guide the design of automated workflows for implementing modeling platforms, to inform human PK/PD and dose projections; Provide scientific and modeling guidance to junior colleagues. Required Skills: Biologics, Biostatistics, Data Analysis, Data Modeling, Data Science, Drug Discovery Process, Interdisciplinary Collaboration, MATLAB, Peptides, Pharmacodynamics, Pharmacokinetics, Pharmacotherapeutics, PKPD Modeling, Proteins, Statistical Analysis, Translational Pharmacokinetics and Pharmacodynamics (PKPD).
Senior Program Manager, Sports Medicine Smith & Nephew PlcSenior Program Manager, Sports MedicineAndover, MA$119,500–$207,250 / yearExperience working within regulated environments, including involvement with regulatory submissions or product clearances, and familiarity with tools such as Jira, Jama, Windchill, Microsoft Project, Planview, Smartsheet, or equivalent platforms. This is an opportunity to work across global, cross functional teams, influence strategic decisions, and drive programs from concept through commercialization while helping improve the lives of patients around the world.
Associate Director, Quantitative Pharmacology and Pharmacometrics, Cardiometabolic Merck & Co IncAssociate Director, Quantitative Pharmacology and Pharmacometrics, CardiometabolicBoston, MA$156,900–$247,000 / yearThe Quantitative Pharmacology and Pharmacometrics (QP2) Department within our Company's Research Laboratories in Rahway, NJ, and West Point, PA is excited to welcome a curious, collaborative, and scientifically driven Associate Director to help support our growing cardiometabolic pipelines. Partner collaboratively with functional area colleagues, external vendors, and strategic partners to build aligned, quantitative, and model-informed approaches that support drug discovery, development, and regulatory decision-making.
Director/Senior Director, CMC Operations Beam Therapeutics IncDirector/Senior Director, CMC OperationsCambridge, MA$210,000–$320,000 / yearLead the preparation of source documentation and technical review of CMC sections for global regulatory submissions specifically focusing on Module 3. Act as the CMC subject matter expert during regulatory meetings and support information requests from regulatory agencies. Beam's suite of gene editing technologies is anchored by base editing, a proprietary technology that is designed to enable precise, predictable and efficient single base changes, at targeted genomic sequences, without making double-stranded breaks in the DNA.
Regulatory & Clinical Specialist LivaNovaRegulatory & Clinical SpecialistBoston, MARemote$85,000–$95,000 / yearManage the overall development and approval process for assigned documents (CEP, CER, etc.) within timelines, including documentation generation, initiation of the review process, discussions on proposed revisions, and document completion in collaboration with other team members. If you are concerned that an offer of employment might be a scam or that the recruiter is not legitimate, please verify by searching for "See Open Jobs" on https://www.livanova.com/en-us/careers , and check that all recruitment emails come from an @livanova.com email address.
Technical Support Specialist WerfenTechnical Support SpecialistBedford, Massachusetts$80,000–$95,000 / yearFull timeMinimum Three years experience in a clinical setting or clinical support role in a regulated environment required Hemostasis: Strong knowledge of Hemostasis/QC required. Provides first line contact and ownership for technical assistance on Werfen products and services, including research, troubleshooting, and identifying solutions to resolve.
Research Associate, Healthcare Wellington ManagementResearch Associate, HealthcareBoston, MassachusettsAdditional qualifications and characteristics include: A minimum of 3 years of relevant investment experience; Prior experience in healthcare or MedTech, Tools or Diagnostics equity research, ideally in a buy-side or sell-side research associate role; Experience analyzing medical device, diagnostics, or life science tools companies, including procedure volumes, utilization trends, industry datasets, clinical data, regulatory pathways, and reimbursement dynamics is preferred; Financial modeling experience, including valuation frameworks for medical device, diagnostics, and tools healthcare companies; Understanding of long/short investing concepts and risk management approaches is beneficial; Strong analytical and problem-solving abilities; High level of intellectual curiosity and willingness to engage deeply with clinical, technical, commercial, reimbursement, and financial material; Strong data and technology skills, including experience using AI and tools to screen, rank, and analyze large stock universes; A willingness to lead effort to integrate AI into research processes; Sound judgment, strong work ethic, and the highest level of personal and professional integrity; Ability to work independently and make decisions in the face of uncertainty; Strong organizational skills and attention to detail; Excellent written and verbal communication skills; and. Analytical acumen and passion for markets –The ideal candidate will possess strong financial modeling skills and the ability to analyze clinical, commercial, regulatory, reimbursement, and financial datasets, while leveraging AI and data tools to drive deeper and more efficient research.
Biologist GlobalchannelmanagementBiologistBoston, MassachusettsBiologist needs 3 years of hands-on laboratory experience (academic or industry) with ELISAs, and automated liquid handlers. Hands-on experience with immunoassay techniques, molecular biology workflows, and laboratory automation platforms.
Research Associate, Healthcare Wellington Management Company, LLPResearch Associate, HealthcareBoston, MAAdditional qualifications and characteristics include: A minimum of 3 years of relevant investment experience; Prior experience in healthcare or MedTech, Tools or Diagnostics equity research, ideally in a buy-side or sell-side research associate role; Experience analyzing medical device, diagnostics, or life science tools companies, including procedure volumes, utilization trends, industry datasets, clinical data, regulatory pathways, and reimbursement dynamics is preferred; Financial modeling experience, including valuation frameworks for medical device, diagnostics, and tools healthcare companies; Understanding of long/short investing concepts and risk management approaches is beneficial; Strong analytical and problem-solving abilities; High level of intellectual curiosity and willingness to engage deeply with clinical, technical, commercial, reimbursement, and financial material; Strong data and technology skills, including experience using AI and tools to screen, rank, and analyze large stock universes; A willingness to lead effort to integrate AI into research processes; Sound judgment, strong work ethic, and the highest level of personal and professional integrity; Ability to work independently and make decisions in the face of uncertainty; Strong organizational skills and attention to detail; Excellent written and verbal communication skills; and. Analytical acumen and passion for markets- The ideal candidate will possess strong financial modeling skills and the ability to analyze clinical, commercial, regulatory, reimbursement, and financial datasets, while leveraging AI and data tools to drive deeper and more efficient research.
Research Fellow, Neuroimaging Brigham and Women's HospitalResearch Fellow, NeuroimagingBoston, MA$70,000–$71,750 / yearResponsibilities include participating in all aspects of data acquisition and management; developing, modifying, and executing analytical protocols; preparing publications and scientific presentations; disseminating results in peer-reviewed scientific journals and at major national and international meetings, and mentoring junior staff. Opportunities exist for excellent scientific interactions and collaborations with an extensive program of seminars, symposia, and other meetings focused on a large array of topics in neuroscience, clinical research, and neurotechnology.
Research Fellow - Deep Learning Brigham and Women's HospitalResearch Fellow - Deep LearningBoston, MA$70,000–$71,750 / yearThe framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. The postdoctoral fellow will be part of a multidisciplinary team of neuroscientists, neurologists, laryngologists, and geneticists at Mass Eye and Ear and Mass General Hospital and work at the intersection on the development, testing and implement of DystoniaNet in the clinical setting.
Program Coordinator II, Part Time Brigham and Women's HospitalProgram Coordinator II, Part TimeBoston, MA$22.22–$31.71 / hourThe Central Venous Catheter (CVC) Program Coordinator provides administrative and operational support to the MGB CVC Safe Insertion Training and Competency Program across Massachusetts General Hospital (MGH) and Brigham and Women's Hospital (BWH), operating under the AMC Office of the Chief Medical Officer. PRINCIPAL DUTIES AND RESPONSIBILITIES: TRAINING SCHEDULING AND COORDINATION: Coordinate with department and training program leaders across both AMCs to enroll and schedule trainees and attendings annually across AMC departments and divisions, ensuring all required participants complete training prior to clinical CVC insertions.
Rehabilitation Aide Brigham and Women's HospitalRehabilitation AideWaltham, MA$17.71–$24.28 / hourPhysical RequirementsStanding Occasionally (3-33%) Walking Occasionally (3-33%) Sitting Constantly (67-100%) Lifting Occasionally (3-33%) 20lbs- 35lbs Carrying Occasionally (3-33%) 20lbs- 35lbs Pushing Rarely (Less than 2%) Pulling Rarely (Less than 2%) Climbing Rarely (Less than 2%) Balancing Occasionally (3-33%) Stooping Occasionally (3-33%) Kneeling Rarely (Less than 2%) Crouching Rarely (Less than 2%) Crawling Rarely (Less than 2%) Reaching Occasionally (3-33%) Gross Manipulation (Handling) Constantly (67-100%) Fine Manipulation (Fingering) Frequently (34-66%) Feeling Constantly (67-100%) Foot Use Rarely (Less than 2%) Vision- Far Constantly (67-100%) Vision- Near Constantly (67-100%) Talking Constantly (67-100%) Hearing Constantly (67-100%). The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success.
NewDirector of Regulatory Affairs, Post-Market Compliance WerfenDirector of Regulatory Affairs, Post-Market ComplianceBedford, Massachusetts$200,000–$240,000 / yearFull timeReporting to the Senior Director of Regulatory Affairs, this position is responsible for ensuring worldwide regulatory compliance of commercially distributed products through effective management of vigilance reporting, field actions, post-market surveillance activities, regulatory assessments, and product lifecycle compliance programs. The Director serves as the regulatory leader for post-market compliance activities and collaborates closely with Quality Assurance, Medical Affairs, R&D, Operations, Manufacturing, Supply Chain, and Commercial teams to ensure timely identification, assessment, communication, and resolution of product-related regulatory issues.
NewResearch Fellow (Miller) Brigham and Women's HospitalResearch Fellow (Miller)Boston, MA$70,000–$71,750 / yearEDUCATION AND EXPERIENCE: Doctoral degree (MD or PhD) with more than 1 year experience in research, with background in mathematics, computational science, computer science, statistics, machine learning, deep learning, computer vision, image processing, biomedical engineering, bioinformatics, visual science and ophthalmology. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success.
NewLate-Stage LNP Process Development Scientist Eurofins Scientific SELate-Stage LNP Process Development ScientistBoston, MA$36–$41 / hourThe successful candidate will have experience with LNP process development (having additional experience in tech transfer and GMP manufacturing is a plus but not required), and a desire to contribute to a team focused on establishing science-based manufacturing solutions for complex nucleic acid-based drug products. Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable.
Post Doctoral Fellow Brigham and Women's HospitalPost Doctoral FellowBelmont, MAMcLean Hospital is seeking a Postdoctoral Research Fellow with a primary focus on investigating the neurobiology of posttraumatic stress disorder (PTSD) and related emotional disorders using magnetic resonance imaging (MRI), including functional MRI. The position offers substantial opportunities for scientific development, including leading manuscripts, presenting findings at national and international conferences, contributing to grant applications, developing new research questions using existing datasets, and building an independent program of research.