Principal Founding Product Engineer PragmatikePrincipal Founding Product EngineerSan Francisco, California$200,000–$350,000 / yearOur client is building highly scalable technology that sits at the core of critical business operations, offering engineers the opportunity to work on complex systems, large-scale integrations, and real-world technical challenges. Pragmatike is recruiting on behalf of a fast-growing technology company building critical infrastructure that powers high-volume, real-time business operations across multiple systems and platforms.
Principal Security Operations Engineer AxonPrincipal Security Operations EngineerSan Francisco, CA$168,750–$270,000 / yearExpert-level Kubernetes experience, with deep hands-on knowledge of cluster architecture, provisioning, upgrades, networking, RBAC, policy enforcement, workload security, and operating production Kubernetes environments at scale. Lead architectural reviews and improvements across Axon's Kubernetes platforms, identifying security, reliability, and operational gaps and partnering with platform teams to implement scalable solutions.
Principal Artificial Intelligence Engineer InnovaccerPrincipal Artificial Intelligence EngineerSan Francisco, CAIn this role, you will work closely with product, engineering, and data teams to design, develop, and deploy AI-powered applications, including LLM-based solutions, AI agents, retrieval-augmented generation (RAG), and intelligent automation workflows. Depth beyond coursework: first-author publications at NeurIPS, ICML, ICLR, ACL, EMNLP, or similar; meaningful open-source ML contributions; a research internship at an AI lab; or models you trained and shipped that people actually used.
Principal Technical Program Manager Atom ComputingPrincipal Technical Program ManagerBerkeley, CA$175,000–$200,000 / yearWe are seeking a Principal Technical Program Manager who will manage operation and upgrades of existing neutral atom quantum computing hardware as well as a portfolio of research projects that advance the Atom Computing roadmap. Work with technical managers and other program managers to balance the time of the technical team in pursuit of advanced tech and main processor line development.
Sr Scientist/Principal Scientist, Discovery Oncology (In Vivo Biology) Eli Lilly and CompanySr Scientist/Principal Scientist, Discovery Oncology (In Vivo Biology)San Francisco, CA$71,250–$187,000 / yearWorking with a high degree of independence under the guidance of a senior scientific lead and/or director, the successful candidate will design, execute, and interpret in vivo (mouse and rat) studies - alongside supporting ex vivo and in vitro assays - to identify and validate novel druggable oncology targets, de-risk on-target toxicity liabilities, and advance targets from the pre-portfolio pipeline into the formal discovery portfolio. Our current groups include: Africa, Middle East, Central Asia (AMECA), Black Employees at Lilly (BE@Lilly), Chinese Culture Network (CCN), EnAble, Evolve, Lilly Indian Network (LIN), Organization of Latinx at Lilly (OLA), Pride (LGBTQ+ Allies), Veterans Leadership Network (VLN) and Women's Initiative for Leading at Lilly (WILL).
Risk Advisory Services Principal Baker Tilly Virchow Krause, LLPRisk Advisory Services PrincipalSanta Rosa, CAWork closely with client executives and management teams to understand their businesses and assist in identifying and managing financial and operational risks within their business systems to ensure technology risks are managed: Develop in-depth knowledge of clients' businesses and industries by having direct client interaction while working on multiple aspects of an engagement. Baker Tilly Advisory Group, LP and Baker Tilly US, LLP, trading as Baker Tilly, are independent members of Baker Tilly International, a worldwide network of independent accounting and business advisory firms in 141 territories, with 43,000 professionals and a combined worldwide revenue of $5.2 billion.
Sr Scientist/Principal Scientist, Discovery Oncology (in vivo Biology) Eli Lilly and CompanySr Scientist/Principal Scientist, Discovery Oncology (in vivo Biology)San Francisco, California$71,250–$187,000 / yearWorking with a high degree of independence under the guidance of a senior scientific lead and/or director, the successful candidate will design, execute, and interpret in vivo (mouse and rat) studies — alongside supporting ex vivo and in vitro assays — to identify and validate novel druggable oncology targets, de-risk on-target toxicity liabilities, and advance targets from the pre-portfolio pipeline into the formal discovery portfolio. Our current groups include: Africa, Middle East, Central Asia (AMECA), Black Employees at Lilly (BE@Lilly), Chinese Culture Network (CCN), EnAble, Evolve, Lilly Indian Network (LIN), Organization of Latinx at Lilly (OLA), Pride (LGBTQ+ Allies), Veterans Leadership Network (VLN) and Women’s Initiative for Leading at Lilly (WILL).
Principal Engineer I/II, MSAT / Viral Vector Downstream Third Rock Ventures LLCPrincipal Engineer I/II, MSAT / Viral Vector DownstreamBerkeley, CA$170,000–$215,000 / yearDefine and lead the external downstream process strategy for Azalea's viral vector programs, with an immediate focus on EDV and AAV manufacturing for Program 1. In collaboration with the PD team, assist with downstream process development, optimization, scale-up, and manufacturing readiness activities across clarification, filtration, chromatography, ultrafiltration/diafiltration, formulation interfaces, sterile filtration, hold-time strategy, and other relevant unit operations. Fraudulent emails claiming to be sent by Azalea or Azalea employees may come from similar sounding emails with endings like "@azaleajobs.com" or "@azalea.com" or even emails ending in common public domain addresses with endings like "@gmail.com,"
Senior Principal Investigator, Crypto Asset Investigations - Tokenized Securities Markets Financial Industry Regulatory Authority, Inc.Senior Principal Investigator, Crypto Asset Investigations - Tokenized Securities MarketsSan Francisco, CAThe Senior Principal Investigator in Crypto Asset Investigations (CAI) conducts high-complexity investigations into crypto asset activities of FINRA member firms and their associated persons; provides subject matter expertise to Regulatory Operations staff on crypto asset matters and initiatives; assists in the development and delivery of crypto asset training for FINRA staff and the securities industry; and assist in external engagements and intelligence sharing initiatives to raise awareness of emerging and priority threats related to crypto asset and blockchain technology, and highlight related challenges and effective practices. FINRA employees are required to disclose to FINRA all brokerage accounts that they maintain, and those in which they control trading or have a financial interest (including any trust account of which they are a trustee or beneficiary and all accounts of a spouse, domestic partner or minor child who lives with the employee) and to authorize their broker-dealers to provide FINRA with duplicate statements for all of those accounts.
Principal Forward Deployed Engineer PragmatikePrincipal Forward Deployed EngineerSan Francisco, California$200,000–$350,000 / yearYou'll work at the intersection of engineering, product, and customers, solving challenging real-world technical problems while directly influencing the evolution of a rapidly scaling technology platform. We are seeking a Principal Forward Deployed Engineer to own some of the company's most technically complex customer deployments and help define how the organization approaches forward deployment at scale.
Principal Software Engineer (YC Experience) PragmatikePrincipal Software Engineer (YC Experience)San Francisco, California$180,000–$300,000 / yearPragmatike is recruiting on behalf of a rapidly scaling technology company seeking a Principal Software Engineer with experience in YC-backed or Venture backed start-ups to provide technical leadership across critical systems and engineering initiatives. Our client is building highly scalable technology that sits at the core of critical business operations, offering engineers the opportunity to work on complex systems, large-scale integrations, and real-world technical challenges.
Senior Principal Program Manager, GTM Excellence RedditSenior Principal Program Manager, GTM ExcellenceSan Francisco, CA$180,200–$313,000 / yearResponsibilities: Support core GTM leadership by managing Reddit's largest OPEX planning cycles, overseeing complex roadmaps, and ensuring decision-ready documents are prepared for monthly engagements with executive leadership, including the CRO and COO. In this heavily executive-facing role, you will operate as a Business Transformation Manager leading large-scale strategic initiatives-specifically owning end-to-end processes, transforming our methodologies, and evolving our systems, data, and products.
Principal-Site Investigation & Remediation (Remote) Kimmel & AssociatesPrincipal-Site Investigation & Remediation (Remote)San Francisco, CARemote$170,000–$200,000 / yearThe successful candidate will have the autonomy and influence to identify opportunities, cultivate strategic client relationships, lead complex projects, and mentor the next generation of technical professionals. Our client is a well-established and highly respected environmental engineering and civil infrastructure firm recognized for technical excellence, responsiveness, and successful project delivery.
Principal AI/ML Engineer PragmatikePrincipal AI/ML EngineerSan Francisco, CaliforniaYou will take technical ownership of critical ML components, lead model development and productionization efforts, and work closely with AI researchers, platform engineers, and product teams to deliver scalable, production-grade AI systems. This role is intended for experienced AI/ML engineers who have already built and deployed models in production environments and want to operate at the intersection of research-quality AI and real-world systems engineering .
Principal Product Operations and Risk Analyst Circle Internet FinancialPrincipal Product Operations and Risk AnalystSan Francisco, CaliforniaRemoteThe role supports the overall Enterprise Risk Management (ERM) Program’s goal of maintaining and growing Circle's resiliency by identifying, assessing, and preparing its operations for any internal and external factors and risks that could interfere with reaching its goals and objectives. Circle’s platform includes the world’s largest regulated stablecoin network anchored by USDC, Circle Payments Network for global money movement, and Arc, an enterprise-grade blockchain designed to become the Economic OS for the internet.
Data Science Principal Slack Technologies LLCData Science PrincipalSan Francisco, CA$197,300–$313,700 / yearWhat you'll be doing: Establish strong partnership with product and business stakeholders in identifying opportunities, prioritize roadmaps, define and implement execution excellence, and coach and mentor team members for execution excellence. As Slack builds out its next generation of Platform capabilities, you'll lead the efforts on unearthing insights and building a complete picture of what users build and how they engage with agents and with each other on the Slack platform.
Snowflake Partner Solution Lead - Senior Principal - West Region Slalom IncSnowflake Partner Solution Lead - Senior Principal - West RegionSan Francisco, CA$158,000–$217,000 / yearRepresenting a Snowflake Elite Services Partner and 7-time Snowflake Partner of the Year, you will act as a senior technical and commercial authority at the intersection of partner strategy, solution leadership, and global go-to-market execution. You will be a trusted advisor to Snowflake, Slalom leadership, and our clients-bringing deep technical expertise, a strong point of view, and the ability to translate Snowflake's platform capabilities into compelling business outcomes.
Principal Program Manager (Req. #6949) 2 Locations Xperi IncPrincipal Program Manager (Req. #6949) 2 LocationsEmeryville, CAAct as the primary program lead for customers, ensuring successful delivery of Xperi's products and services, across multiple phases of the integration; pre-requisites, delivery, testing, launch, go-to-market planning, and operational readiness activities. This role also serves as a critical bridge between other agile squads within the Customer Success organization as well as with Xperi's Product, Engineering, Operations, Support, and external customers, driving execution excellence while scaling operational processes, governance, and delivery frameworks.
Principal AI Researcher InnovaccerPrincipal AI ResearcherSan Francisco, CAIn this role, you will work closely with product, engineering, and data teams to design, develop, and deploy AI-powered applications, including LLM-based solutions, AI agents, retrieval-augmented generation (RAG), and intelligent automation workflows. Depth beyond coursework: first-author publications at NeurIPS, ICML, ICLR, ACL, EMNLP, or similar; meaningful open-source ML contributions; a research internship at an AI lab; or models you trained and shipped that people actually used.
Associate Director, Principal Data Engineer Vir BiotechnologyAssociate Director, Principal Data EngineerSan Francisco, CA$176,500–$246,500 / yearThe ideal candidate is a forward-thinking technical leader who combines expertise in data engineering, scientific software, AWS cloud platforms, and practical AI implementation to transform complex scientific data into connected, searchable, and actionable insights. Vir Biotechnology is seeking an Associate Director, Principal Data Engineer to lead scalable data, cloud, software, and AI-enabled research platforms that support scientific discovery, clinical data analysis, and program decision-making.