Machine Learning Scientist, Applied Machine Learning and Agentic AI, Pharma R&D Tempus AI IncMachine Learning Scientist, Applied Machine Learning and Agentic AI, Pharma R&DBoston, MA$100,000–$150,000 / yearThe Machine Learning Scientist, Applied Machine Learning and Agentic AI will contribute to the technical development of cutting-edge agentic frameworks designed to automate the discovery of novel prognostic and predictive models in oncology. You will apply advanced scientific methodologies to develop new predictive models and utilize causal inference frameworks to analyze vast multimodal oncology data, helping to scale scientific discovery from a manual process to a high-throughput, automated engine.
Associate Director - Computational Biology (Cardiovascular, Metabolic, Obesity and Related) Amgen IncAssociate Director - Computational Biology (Cardiovascular, Metabolic, Obesity and Related)Cambridge, MA$182,465–$246,865 / yearThe Computational Biology group in the Center for Technology and Innovation (CfTI) within the Precision Medicine organization at Amgen is seeking a highly motivated Computational Biologist with expertise in analyzing clinical biomarker data, including but not limited to metabolomics, genomics, transcriptomics, proteomics, spatial-omics, flow cytometry, immunoassays, and other biomarker assays. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
Data Analyst Brigham and Women's HospitalData AnalystBoston, MAMasters degree preferred but not required (MS, MA, or MPH), preferably focusing on applied mathematics, decision science, data science, biostatistics, statistics, computer science, computational biology and/or economics, with a strong background in quantitative coursework and research. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success.
Director, Medical Writing Alkermes PlcDirector, Medical WritingWaltham, MAThe Director is accountable for document development strategy, planning, and execution; leads clinical content development for complex submissions (including content strategy, organization, and resourcing); and partners with Clinical Development, Regulatory Affairs, Biostatistics, and other key functions to ensure cohesive messaging, mitigate risk, and support successful regulatory interactions and filings. In 2024 and 2025, we were certified as a Great Place to Work in the U.S. and named one of Massachusetts' Top Places to Work by the Boston Globe, a Best Place to Work in Greater Cincinnati by the Cincinnati Business Courier and recognized as a Best Place to Work in BioPharma by Fortune Magazine.
Director, Medical Affairs, Rare Disease ImCheck Therapeutics SASDirector, Medical Affairs, Rare DiseaseCambridge, MA$225,000–$300,000 / yearThe role also includes oversight of medical information responses (in collaboration with Medical Information), scientific communications (including publications and congress presentations in partnership with the Publication team), and the design and medical oversight of US based clinical studies, as well as the review and approval of promotional and medical materials and educational grants. The Director works closely with the Medical Science Liaison team to guide field medical strategy, develop and maintain relationships with key opinion leaders, and incorporate field insights into medical planning.
Sr. Medical Director, Medical Affairs (Alixorexton) Alkermes PlcSr. Medical Director, Medical Affairs (Alixorexton)Waltham, MAThe incumbent will need to understand the business strategies and drivers underlying our Alixorexton program, translating those drivers into strategies and data generation and communication plans that contribute to a successful product launch, and ensure alignment of Alixorexton activities across our neuroscience portfolio. In 2024 and 2025, we were certified as a Great Place to Work in the U.S. and named one of Massachusetts' Top Places to Work by the Boston Globe, a Best Place to Work in Greater Cincinnati by the Cincinnati Business Courier and recognized as a Best Place to Work in BioPharma by Fortune Magazine.
Sr. Manager - Clinical Trial Lead Biogen IncSr. Manager - Clinical Trial LeadCambridge, MA$141,000–$188,000 / yearThe Senior Manager, CTL, leverages their phase, indication and operational expertise to independently manage and ensure delivery of one or more clinical studies, including: Partnering with cross-functional representatives to drive the development of operationally feasible and robust protocol designs, ensuring that principles of patient focus, risk management, quality and scientific integrity are applied, exercising appropriate budget responsibility and focused, endpoint-driven cost consideration. As required, collaborates strategically with the core SMT (study MD, biostatistics, etc.) and other key program team members to provide direction on phase, disease, or therapeutic area to support study design in alignment with the Integrated Asset Plan (IAP) and Program Operational Plan (POP), enabling protocol concept development and driving forward studies through governance approval.
Senior Director, Bioanalytical And Biomarker Development Editas Medicine, Inc.Senior Director, Bioanalytical And Biomarker DevelopmentCambridge, MA$270,000–$300,000 / yearThis highly visible role will be accountable for the preclinical bioanalytical strategy, biomarker strategy, data quality, and regulatory readiness, ensuring successful EDIT-401 IND submission and Clinical Trial execution. Characterizing Your Impact: As the Senior Director, Bioanalytical and Biomarker Development, you will: Lead assay development, qualification, validation, and execution for measuring drug product components, immunogenicity, biomarkers, and other analytes in biological matrices.
Senior Director, Clinical Operations Kymera Therapeutics IncSenior Director, Clinical OperationsWatertown, MA$235,000–$330,000 / yearHaving advanced the first degrader into the clinic for immunological diseases, Kymera is focused on building an industry-leading pipeline of oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions. How you'll make an impact: The Senior Director, Clinical Operations is a leadership role responsible for overseeing and managing all aspects of clinical operations for the Phase 3 program of a high priority immunology program, KT-621.
Clinical Trial Manager/Senior Clinical Trial Manager Oruka Therapeutics IncClinical Trial Manager/Senior Clinical Trial ManagerWaltham, MA$146,000–$161,000 / yearOruka's mission is to offer patients suffering from chronic skin diseases like plaque psoriasis the greatest possible freedom from their condition by achieving high rates of complete disease clearance with dosing as infrequently as once or twice per year. Key Responsibilities: Clinical Trial Management: Lead and manage multiple clinical trials from initiation through to completion, ensuring adherence to study timelines and budgets.
Associate Director, Medical Writing Alkermes PlcAssociate Director, Medical WritingWaltham, MAThe Associate Director is accountable for document development strategy, planning, and execution; leads clinical content development for complex submissions (including content strategy, organization, and resourcing); and partners with Clinical Development, Regulatory Affairs, Biostatistics, and other key functions to ensure cohesive messaging, mitigate risk, and support successful regulatory interactions and filings. In 2024 and 2025, we were certified as a Great Place to Work in the U.S. and named one of Massachusetts' Top Places to Work by the Boston Globe, a Best Place to Work in Greater Cincinnati by the Cincinnati Business Courier and recognized as a Best Place to Work in BioPharma by Fortune Magazine.
Senior Director, Clinical Quality Assurance Alkermes PlcSenior Director, Clinical Quality AssuranceWaltham, MAA member of the Alkermes Quality leadership team responsible for overall Quality culture and continuous improvement of Alkermes QMS and compliance, and leads the Alkermes strategy and GXP compliance on all matters concerning Quality in the areas of; Good Laboratory Practices (GLP), Good Clinical Practices (GCPs), and Good Pharmacovigilance Practices pre and post market (GVPs). Oversee the development, implementation, and continuous improvement of clinical quality systems, harmonized GCP/GVP/GLP Policies, processes, SOPs, and governance structures collaborating closely with Clinical Department, related functions and external partners to comply with global requirements.
Senior Director, Clinical Dosimetry & Radiation Sciences Alpha-9 OncologySenior Director, Clinical Dosimetry & Radiation SciencesBoston, MassachusettsThis role operates at the intersection of clinical development, clinical pharmacology, regulatory affairs, and external imaging partners, with direct influence on how quantitative radiopharmaceutical data is translated into clinical decisions. Reporting into Clinical Development, this role serves as the internal scientific lead for dosimetry methodology and imaging quantification, ensuring rigor, consistency, and interpretability across multiple active studies.
Senior Director, Program & Portfolio Management Vera TherapeuticsSenior Director, Program & Portfolio ManagementBoston, MassachusettsThis person will also lead the Research and Development Governance and will partner closely with the Global Program Team Lead (GPTL) and the Global Program Team (GPT) Program Manager to ensure strategic direction set by the GPT translates into clear, well-coordinated execution across Program Teams and Governance Forums. Serve as the principal execution partner to the Global Program Team Lead (GPTL) and GPT Program Manager, translating GPT-level strategy into coordinated execution plans and ensuring program risk and status are communicated clearly across governance layers.
Analyst, Statistical Programming Biogen IdecAnalyst, Statistical ProgrammingCambridge, MA$81,000–$111,000 / yearThe Analyst, Statistical Programming supports statistical programming activities across clinical development programs, partnering with Biostatistics, Data Management, and external vendors to deliver high-quality, submission-ready statistical outputs. Regular employees are eligible to receive both short term and long-term incentives, including cash bonus and equity incentive opportunities, designed to reward recent achievements and recognize your future potential based on individual, business unit and company performance.
Associate Director - Computational Biology (Cardiovascular, Metabolic, Obesity And Related) Amgen Inc.Associate Director - Computational Biology (Cardiovascular, Metabolic, Obesity And Related)Cambridge, MA$182,465–$246,865 / yearThe Computational Biology group in the Center for Technology and Innovation (CfTI) within the Precision Medicine organization at Amgen is seeking a highly motivated Computational Biologist with expertise in analyzing clinical biomarker data, including but not limited to metabolomics, genomics, transcriptomics, proteomics, spatial-omics, flow cytometry, immunoassays, and other biomarker assays. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
Translational Scientist, Applied Machine Learning And Agentic AI, Pharma R&D TempusTranslational Scientist, Applied Machine Learning And Agentic AI, Pharma R&DBoston, MA$100,000–$150,000 / yearYou will apply advanced scientific methodologies to develop new predictive models and utilize causal inference frameworks to analyze vast multimodal oncology data, helping to scale scientific discovery from a manual process to a high-throughput, automated engine. The Translational Scientist, Applied Machine Learning and Agentic AI will contribute to the technical development of cutting-edge agentic frameworks designed to automate the discovery of novel prognostic and predictive models in oncology.
NewSenior Scientist I, Translational Research Tempus AI IncSenior Scientist I, Translational ResearchBoston, MA$100,000–$160,000 / yearDemonstrated ability to influence without authority (both with internal and external stakeholders Proactive mindset that bridges ideas to implementable solutions, and can help move both internal and external stakeholders to quickly solve problems Experience with communicating insights and presenting concepts to diverse audiences. Work with Product and Engineering teams to streamline workflow of computational analyze Contribute to the development of the portfolio by providing feedback to leadership regarding client responses and suggestions; maintain a solution-oriented mindset.
Senior Scientist I, Translational Research TempusSenior Scientist I, Translational ResearchBoston, MA$120,000–$170,000 / yearDemonstrated ability to influence without authority (both with internal and external stakeholders Proactive mindset that bridges ideas to implementable solutions, and can help move both internal and external stakeholders to quickly solve problems Experience with communicating insights and presenting concepts to diverse audiences. Work with Product and Engineering teams to streamline workflow of computational analyze Contribute to the development of the portfolio by providing feedback to leadership regarding client responses and suggestions; maintain a solution-oriented mindset.
Clinical Development Scientist, Senior Manager Pfizer IncClinical Development Scientist, Senior ManagerCambridge, MA$139,100–$231,900 / yearSubject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Authors and reviews key clinical and regulatory documents including, but not limited to, protocols, study-level informed consent forms (ICFs), Investigator's Brochures (IBs), clinical study reports (CSRs), and regulatory submission components.