Senior Product Partnerships Manager SimpleClosureSenior Product Partnerships ManagerSan Francisco, New York$160,000–$230,000 / yearYou'll operate cross-functionally at the highest level, working directly with the CEO and partnering closely with R&D and GTM to identify, structure, and execute strategic partnerships with technology platforms, financial services, and ecosystems that touch founders at key inflection points. This person builds deep, integrated relationships — not a traditional channel or referral partnerships role, but one focused on high-impact deals that embed SimpleClosure into the products and platforms founders already rely on.
Senior Scientist, Bio AI EarliSenior Scientist, Bio AIRedwood City, CA$205,000–$235,000 / yearPerform routine bioinformatic analyses on multi-modal omics data (RNAseq and scRNA-seq, ATAC-seq, proteomics, phospho-proteomics etc.) using individual as well as coherent multi-omic ML-based pipelines to identify key dysregulated targets and pathways in selected cancer indications. Master's or PhD degree in a relevant field (bioengineering, computer science, data science, etc.) with a minimum of 3 years of hands-on experience using AI/ML applied to genomic/bioinformatic data using state-of-the-art GenAI models.
Scientist/Sr Scientist, Protein Engineering EarliScientist/Sr Scientist, Protein EngineeringRedwood City, CA$110,000–$145,000 / yearDesign novel protein therapeutics-including cytokines, immune agonists, fusion proteins, bispecific constructs (multi-domain and 2A-based), leveraging structure-function knowledge and/or computational tools to guide engineering hypotheses. Design, develop, and execute functional assays in relevant cancer cell lines and primary human immune cells (PBMCs, T cells, NK cells, monocytes/macrophages) to evaluate candidate activity, potency, and selectivity.
Engineering Manager, Platform AirbyteEngineering Manager, PlatformSan Francisco, CaliforniaAs an Engineering Manager on the Platform team, you'll lead the engineers responsible for cloud infrastructure, deployment systems, CI/CD, observability, reliability, and the internal tooling that powers engineering velocity across the company. Invest in and drive adoption of AI-powered workflows for debugging, release validation, infrastructure management, and developer productivity, moving past experimentation into real operational leverage.
Product Manager, Agent Development - Healthcare SierraProduct Manager, Agent Development - HealthcareSan Francisco, CaliforniaOur healthcare customers include major health insurance networks, nonprofit providers, multi-site primary and urgent care practices, healthcare diagnostics companies, and healthcare financial platforms. Build enterprise-grade AI agents for healthcare: As an Agent PM at Sierra, you will be responsible for partnering directly with our engineers and customers to build and ship AI agents that handle thousands of customer conversations a day.
Payroll Lead SierraPayroll LeadSan Francisco, CaliforniaServe as a trusted advisor to employees and leaders , providing clear guidance on payroll, taxes, and equity, while managing third-party vendors for quality and accuracy. As our Payroll Manager, you will own and evolve Sierra’s global payroll operations, ensuring accuracy, compliance, and an exceptional experience for employees across multiple regions.
Founding Marketer QuantaFounding MarketerSan Francisco, California$150,000–$225,000 / yearPlan and create high-quality content across all mediums — including blog, social, and email — including customer stories, launch posts, and thought leadership pieces. By operating directly on real customer data and real workflows, we turn messy, judgment-heavy financial data into a reliable, queryable system of record.
Security and Compliance Manager SierraSecurity and Compliance ManagerSan Francisco, CaliforniaYou will act as a strategic partner to Platform, Product, Agent Development, Legal, and GTM, ensuring security and compliance requirements are embedded into architecture decisions, product roadmaps, and go to market execution while supporting product velocity and technical complexity. Design and operate automated compliance workflows using AI, infrastructure as code, and security tooling to reduce manual effort, improve control assurance, and scale with platform evolution.
Software Engineer TonicSoftware EngineerSan Francisco, CAWe are backed by top-tier investors from Accel, a16z, Patron, and Sequoia, alongside individuals including Pharrell Williams, Packy McCormick, Steve Chen (cofounder Youtube), Kevin Lin (cofounder Twitch), Bob Meese (CBO Duolingo), Marc Merrill (cofounder Riot Games), Lucy Guo (cofounder Scale), Rajiv Ayyangar (CEO ProductHunt), and many more. • Provide thoughtful feedback on Pull Requests, Product Briefs, and ADRs, helping the Tonic Dev Team grow in the quality of code and the way they think about product and technical decisions.