Sr. Director, Clinical Outsourcing and Vendor Management City TherapeuticsSr. Director, Clinical Outsourcing and Vendor ManagementCambridge, Massachusetts$253,333–$286,667 / yearReporting to the Vice President of Clinical Operations, this individual will serve as the primary business owner for key clinical vendors, including CROs, central laboratories, imaging providers, eCOA/ePRO vendors, IRT providers, and specialty service partners. The successful candidate will establish scalable vendor governance processes, ensure operational excellence, and drive accountability across external partnerships while supporting the execution of City's clinical development programs.
Medical Director, Oncology Clinical Development - GU GSK plcMedical Director, Oncology Clinical Development - GUWaltham, MA$189,750–$316,250 / yearAnalytical Thinking, Clinical Data Interpretation, Clinical Data Review, Clinical Development, Clinical Trial Designs, Clinical Trials Monitoring, Digital Fluency, Drug Regulatory Affairs, Executive Presence, Hematology and Oncology, Learning Agility, Matrix Leadership, Real World Evidence (RWE), Scientific Presentations. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients' needs and have the highest probability of success.
Medical Director, Clinical Science, Neuroscience TAU- Psychiatry 3316 Takeda Development Center AmericasMedical Director, Clinical Science, Neuroscience TAU- PsychiatryMassachusettsAssesses scientific, medical, and development feasibility, evaluating strategic fit with overall portfolio, evaluating complete or ongoing clinical trials, assessing regulatory interactions and future development plans, interacting with upper management of potential partner/acquisition companies during DD visits and alliance negotiations, and representing clinical science on internal assessment teams in conjunction with GPLS & Business Units. These responsibilities include leadership roles in meetings with the regulatory organizations or key opinion leaders, establishment of strategy for assigned compounds, and the direction of clinical scientists involved in developing documents required to outline the Company positions on research programs or regulatory applications (e.g.
Executive Medical Director, Clinical Development, Hematology AstraZeneca PlcExecutive Medical Director, Clinical Development, HematologyBoston, MAThe Executive Medical Director (EMD) role is generally assigned to be responsible for overseeing 2 or more programs, providing oversight/guidance/mentoring to the Medical Directors and Clinical Development Scientists on the teams, serving on cross-asset strategic teams (e.g., disease strategy team) and providing input to strategic decisions at the TA Strategy Team and Global Medicine Team meetings. Representing Clinical Development on the Global Program Team (GPT) and Global Medicine Team in presentations at management and review committees (e.g., Clinical Document Review Committee, Development and Commercial Steering Committee); advance understanding of the impact our therapies have on the pathophysiology of rare and orphan diseases through scientific discourse and interpretation of data.
Medical Director, Oncology Clinical Development - Hematology GSK plcMedical Director, Oncology Clinical Development - HematologyWaltham, MA$222,750–$371,250 / yearAnalytical Thinking, Clinical Data Interpretation, Clinical Development, Clinical Pharmacology, Clinical Trial Designs, Clinical Trials Monitoring, Digital Fluency, Drug Regulatory Affairs, Evidence Based Decision Making, Executive Presence, Hematology and Oncology, Learning Agility, Matrix Leadership, Real World Evidence (RWE), Scientific Presentations. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients' needs and have the highest probability of success.
Director, Clinical Data & AI Smith & Nephew PlcDirector, Clinical Data & AIAndover, MA$165,250–$236,000 / yearThis role owns the clinical data lifecycle-from data acquisition and management to advanced analytics, AI enablement, and synthetic/simulated data-ensuring all data assets are high-quality, interoperable, and fit-for-purpose for regulatory, scientific, and operational decision-making. The Director serves as the enterprise authority on clinical data platforms and AI-enabled evidence generation, driving integration across clinical systems, data engineering, AI/ML, and statistical/clinical programming.
Clinical Scientific Director 3316 Takeda Development Center AmericasClinical Scientific DirectorMassachusettsData Science or Clinical Operations, and Drug Discovery Unit and other preclinical functions based on pertinent clinical and development expertise to provide knowledge / understanding of market environment in line with status as scientific content matter expert for assigned compounds. Education and experience: Advanced life science degree or internationally recognized equivalent plus 3 years of clinical research experience within the pharmaceutical industry, CRO health-related consulting company, or biomedical/clinical experience within academia (or a combination of afore mentioned).
NewSenior Director of Clinical Science - Hematology Merck & Co IncSenior Director of Clinical Science - HematologyBoston, MA$190,800–$300,300 / yearThe Senior Director partners closely with Section Heads, Asset Leads, Program Development Team Leads, and cross-functional development team members to support study planning, data interpretation, issue resolution, and broader program decisions across assigned studies and programs. Required Skills: Change Agility, Clinical Development, Clinical Oncology, Clinical Reporting, Clinical Research, Clinical Sciences, Clinical Study Management, Clinical Trial Management, Hematology, Medical Sciences, Oncology, People Leadership, Scientific Literacy.
Director, Clinical Monitoring Strategy and Oversight ModernaTXDirector, Clinical Monitoring Strategy and OversightCambridge, MassachusettsThe Director serves as the functional leader for monitoring strategy, integrating risk-based monitoring (RBM), centralized monitoring, remote monitoring, and emerging digital capabilities into a scalable oversight framework for both insourced and outsourced monitoring strategies. We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S. If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities.
Medical Writer Clinical Development The Fountain Group LLCMedical Writer Clinical DevelopmentMarlborough, MARemoteExperience authoring or reviewing Clinical Study Reports (CSRs), clinical study protocols, protocol amendments, and Investigator Brochures (IBs) . Integrate scientific and clinical information from Clinical Development, Clinical Operations, Biostatistics, Data Management, Regulatory Affairs, Pharmacovigilance, and Medical Affairs functions.
Senior Director, Clinical Operations Kymera TherapeuticsSenior Director, Clinical OperationsWatertown, MA$235,000–$330,000 / yearHaving advanced the first degrader into the clinic for immunological diseases, Kymera is focused on building an industry-leading pipeline of oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions. Accountable for robust operational strategies for all studies in the Phase 3 program, ensuring consistency as needed, including country and site mix, PR&R and Site Engagement strategies, vendor strategy, risk based and site monitoring strategies, etc.
NewDirector of Clinical Pharmacology, Cambridge, MA Isomorphic Labs LimitedDirector of Clinical Pharmacology, Cambridge, MACambridge, MACRO Management: Oversee and partner with global clinical CROs to ensure the high-quality, timely, and cost-effective execution of clinical pharmacology studies and human bioanalysis and PK data analyses within broader oncology and non-oncology clinical trials. Data Analysis: Direct the analysis, interpretation, and reporting of bioanalytical PK data from clinical trials and human AME (mass balance) studies; utilize appropriate modeling approaches (e.g., PopPK, exposure-response) to inform dose optimization and the recommended phase 2 dose/schedule (RP2D) selection for pivotal studies.
NewSenior Director of Clinical Science - Lung Merck & Co IncSenior Director of Clinical Science - LungBoston, MA$190,800–$300,300 / yearThe Senior Director partners closely with Section Heads, Asset Leads, Program Development Team Leads, and cross-functional development team members to support study planning, data interpretation, issue resolution, and broader program decisions across assigned studies and programs. The Senior Director, Clinical Science - Lung is responsible for providing strategic Clinical Science leadership across the lung disease area, with accountability spanning multiple studies, programs, and assets.
Engagement Manager- Primary Market Research Trinity Life SciencesEngagement Manager- Primary Market ResearchWaltham, MA$136,000–$204,000 / yearWell-developed expertise across a wide range of primary research methodologies applied to various business needs, including forecasting, positioning, customer segmentation, product development, pricing studies, tracking studies, burden of illness studies, patient journey studies, patient preference studies, etc. Trinity's salary bands account for a wide range of factors that are considered in making compensation decisions including but not limited to skill sets and market demand for skills; level of experience and training; specific qualifications, performance, time in role/company, geographic location, and other business and organizational needs.
Associate Director, CMC Lead AstraZeneca PlcAssociate Director, CMC LeadBoston, MA$136,514–$204,771 / yearClinical Supply Strategy: Build and execute supply strategies for Phase 0/Phase I, aligning isotope availability, shelf life, and study timelines to ensure on-time, fit-for-purpose clinical material. Portfolio Leadership: Manage multiple early-stage programs; set priorities, balance resources, and adjust strategies as data emerge to protect the critical path.
Director, Clinical Development Scientist (Non-MD) Pfizer IncDirector, Clinical Development Scientist (Non-MD)Cambridge, MA$176,600–$294,300 / yearProvides clinical guidance to the development of the clinical data collection strategy, instruments, and data review plan, ensuring alignment with the protocol and SAP, optimized data collection principles, and clinical data review best practice; sets the clinical data review strategy and leads the team in the review of emerging clinical data and trends; reviews and queries data; presents data to internal and external stakeholders; partners with site-facing colleagues in support of data issue resolution; ensures all clinical queries are appropriately addressed in support of database lock. Provides clinical guidance to the development of the Safety Review Plan and Safety Narrative Plan; reviews safety data and ensures clinical documents are updated in response to emerging safety profile; tracks and reconciles Serious Adverse Events; leads clinical safety data discussion during Safety Review Team meetings in collaboration with Medically Qualified Individual(s); reviews safety narratives.