Principal Associate I, Plant Quality Assurance - 2ND SHIFT ReplimunePrincipal Associate I, Plant Quality Assurance - 2ND SHIFTFramingham, Massachusetts$120,000–$155,000 / yearThe Principal Associate I/II, Plant Quality Assurance (PQA) reports to the Associate Director, Quality Assurance and is responsible for on-going Quality oversight to ensure real time quality oversight for Drug Substance, Drug Product, and all other production and QC testing activities according to current good manufacturing practices (cGMP), good documentation practices (GDP) and other applicable regulations. The RPx platform is designed to have a unique dual local and systemic activity consisting of direct selective virus-mediated killing of the tumor resulting in the release of tumor derived antigens and altering of the tumor microenvironment to ignite a strong and durable systemic response.
Principal Data Strategist, Real World Evidence Gateway RecruitingPrincipal Data Strategist, Real World EvidenceBoston, MAThis incumbent will be operating with a high degree of autonomy, this individual will shape fit-for-purpose RWD strategies, evaluate and operationalize external data assets, and lead advanced analytics initiatives using EHRs, claims, registries, and linked healthcare data. The Principal Data Strategist, Real World Evidence (RWE) will lead enterprise real-world data (RWD) strategy and advanced analytics initiatives that support scalable, regulatory-aligned evidence generation.
Principal Mechanical Engineer Berkshire Grey Inc.Principal Mechanical EngineerBedford, MAThe candidate must be highly experienced and autonomous with respect to designing, fabricating, and testing new designs, as well as launching new products into production and supporting systems fielded at customer sites. Significant experience designing systems that are used in industrial settings, expecting to balance cost and durability for maximum customer success over the capital equipment's full depreciation lifespan.
Principal Modeling And Simulation Engineer Berkshire Grey Inc.Principal Modeling And Simulation EngineerBedford, MAIn the role of Principal Modeling and Simulation Engineer, you will lead the development of high-fidelity simulation platforms and digital twins that drive system design, validation, and deployment. This role blends advanced software engineering with modeling and simulation, enabling rapid development, testing, and optimization of complex robotic systems.
Principal Consultant - Life Sciences LumanityPrincipal Consultant - Life SciencesBoston, MassachusettsAs a trusted advisor to senior leaders across the life sciences industry, you will lead complex consulting engagements, cultivate long-term client relationships, identify new business opportunities, and mentor high-performing consulting teams. As a global strategic partner that brings together strategy, evidence, engagement, and technology, we were designed to engineer breakthrough value to tackle our clients’ toughest challenges by revolutionizing how value is generated, demonstrated, and communicated.
Principal Product Manager - Low Voltage VEIRPrincipal Product Manager - Low VoltageWoburn, Massachusetts$170,000–$200,000 / yearComplete the full Preliminary Design phase product deliverable set for the SL Series in collaboration with SL Series subsystem product managers and product marketing manager, including application and use case presentations, product brochure, product presentations, guide specifications, product datasheets, and serviceability plan. The Principal PM is the primary product authority for VEIR’s low voltage system platform — translating data center customer requirements into precise product direction, orchestrating subsystem product managers to ensure cohesive system-level execution, and serving as the product team's primary interface for commercial engagements.
Associate Principal Threat Intelligence Analyst Rockstar GamesAssociate Principal Threat Intelligence AnalystAndover, MA$125,000–$150,000 / yearIf hired, employee will be in an "at-will position" and the company reserves the right to modify base salary (as well as any other discretionary payment or compensation or benefit program) at any time, including for reasons related to individual performance, company or individual department/team performance, and market factors. Become part of a team working on some of the most rewarding, large-scale creative projects to be found in any entertainment medium - all within an inclusive, highly-motivated environment where you can learn and collaborate with some of the most talented people in the industry.
Principal Systems Management Analyst - Epic Healthy Planet UnitedHealth Group Inc.Principal Systems Management Analyst - Epic Healthy PlanetAuburndale, MA$112,700–$193,200 / yearAs a Principal Systems Management Analyst focusing on Epic Healthy Planet and Epic Cheers, you will partner with clinical, operational, and technical leadership to drive population health strategies and patient engagement workflows. Evaluate current-state workflows and identify opportunities to optimize Healthy Planet functionality to improve care gap closure, patient outreach, quality performance, and provider efficiency.
Principal Systems Engineer – Quantum Computing Systems QuEra ComputingPrincipal Systems Engineer – Quantum Computing SystemsBoston, MassachusettsThe ideal candidate brings extensive experience building complex hardware–software systems (e.g., aerospace, EVs, robotics, advanced instrumentation) and is motivated to apply systems engineering rigor in a learning-driven R&D environment , pairing closely with internal quantum experts. We are seeking a Principal Systems Engineer to play a critical role in aligning engineering execution with scientific and machine-level progress in the development of large-scale quantum computers.
Principal Electrical Engineer RE Build Manufacturing, LLCPrincipal Electrical EngineerWilmington, MA$165,000–$250,000 / yearAn experienced engineering leader with a broad range of electrical engineering disciplines, including analog and digital circuit design, power electronics, PCB design, sensors, instrumentation, embedded electronics, and electromechanical systems. We operate an advanced, end-to-end manufacturing platform that partners with industrial companies and innovators to take products from first concept to full-scale production in critical verticals including aerospace and defense, electrification, medical, energy and environment, and robotics and automation.
NewPrincipal AI Program Manager, Appeals Innovation And Automation - Remote UnitedHealth Group Inc.Principal AI Program Manager, Appeals Innovation And Automation - RemoteBoston, MARemote$91,700–$163,700 / yearThis role serves as the bridge between business operations, clinical leadership, technology teams, legal, compliance, privacy, security, and enterprise governance to ensure the responsible deployment of AI capabilities that improve quality, efficiency, consistency, and user experience. The ideal candidate will possess deep expertise in AI agents, workflow automation, generative AI, and healthcare operations, with a proven ability to translate business challenges into AI-enabled solutions.
NewPrincipal Data Engineering - Remote - CST UnitedHealth Group Inc.Principal Data Engineering - Remote - CSTBoston, MARemote$112,700–$193,200 / yearDeploy AI and Data-Driven Solutions: Develop and deploy large-scale data pipelines empowering machine learning algorithms, insights generation, business intelligence dashboards, reporting, and new data products while utilizing enterprise-approved AI tools to address complex business challenges. Working with advanced platforms such as Azure Databricks, Snowflake, and LLMs, you will build data solutions that empower machine learning, insights generation, and business automation, directly contributing to better clinical and administrative connectivity across the healthcare system.
NewPrincipal Software Engineer, Semantic Data Services WEX Inc.Principal Software Engineer, Semantic Data ServicesBoston, MA$200,600–$250,400 / year10+ years of experience in software engineering, data engineering, distributed systems, data platforms, or related technology areas, with demonstrated experience operating at Staff, Principal, or equivalent technical scope. Experience with technologies such as Spark, Flink, Kafka, Iceberg, Snowflake, Databricks, cloud-native data services, graph databases, or equivalent large-scale data technologies.
NewPrincipal Engineer, Process Development Sarepta Therapeutics Inc.Principal Engineer, Process DevelopmentBedford, MA$136,000–$170,000 / yearThe ideal candidate will bring deep experience in complex biologics or bioconjugate manufacturing, hands-on analytical capability such as HPLC, strong knowledge of cGMP and CMC expectations, and the communication and cross-functional leadership skills needed to advance programs from development through late-stage clinical or commercial production. Technical background in AOC, antibody-drug conjugates, bioconjugates, oligonucleotide therapeutics, Fab/antibody intermediates, AAV vectors, viral vector manufacturing, or other complex biologics is strongly preferred.
Investment Principal, Public Markets Partners Capital Investment Group LLPInvestment Principal, Public MarketsBoston, MA$160,000–$220,000 / yearPart timeThe primary goal of the Public Markets Research Team is to deliver high absolute and relative returns over the long-term by partnering with of top-tier managers and select direct investments. In addition to the above, you will, for variety, take on other activities and projects, which might include researching and improving our portfolio construction knowledge and approach, assisting with business development, or helping to develop our technological capabilities.
Client Service Principal, Taxable Partners Capital Investment Group LLPClient Service Principal, TaxableBoston, MA$115,000–$160,000 / yearPart timeHands-on experience servicing US taxable clients (HNW families and family offices), including multi-entity household structures, tax-aware investment operations, and coordination with external CPAs and trust & estate counsel. Proactively identify and mitigate potential risks related to client accounts, working internally to identify, assess, and mitigate risks associated with client accounts and operational processes.
Principal Radar Software Engineer MatrixSpacePrincipal Radar Software EngineerBurlington, MA$175,000–$210,000 / yearYou'll work alongside world-class engineers, tackle challenging multidisciplinary problems, and have the opportunity to make a lasting impact on the future of sensing technology. Candidates must be legally authorized to work in the United States without employer sponsorship and maybe required to obtain and maintain a U.S. government security clearance in the future.
Principal MRB Engineer BelcanPrincipal MRB EngineerLynn, MA$104,000–$145,600 / yearA Principal MRB Engineer is needed to support the needs and goals of manufacturing teams with engineering substantiation reviews to determine the acceptability of aircraft engine hardware. Mentor and develop Junior Engineers who perform analysis to document acceptability of parts to include stresscalculations, tolerance stack ups, and leveraging of previous analysis.*
Principal Systems Engineer - CLEARANCE REQUIRED BelcanPrincipal Systems Engineer - CLEARANCE REQUIREDTewksbury, MAACTIVE US Secret Clearance REQUIREDDesired Skill Sets:* Experience using test equipment, software installations, and integrating or regression testing systems with certifications in CompTIA Network+ and or CompTIA Security+.* Experience with MATLAB, Linux Operating Systems (Linux Red Hat), Unix, Perl, C/C++, and Shell scripting for performing integration, verification and test analysis, integrating and configuring electronics/network routers, and installing/debugging software.* Experience with agile and DevSecOps processes, implement (or maintain) agile methodologies, participating in daily team standup meetings, sprint reviews, program Increment (PI) Planning meetings, retrospectives, and agile tooling such as JIRA and Confluence, and support execution of the team"s backlog including performance analysis and issue investigation.*
Principal Acquisition Program Manager Applied Research SolutionsPrincipal Acquisition Program ManagerBedford, Massachusetts$175,000–$195,000 / yearApplied Research Solutions (ARS) is respected as a world-class provider of technically integrated solutions as we deliver premier talent and technology across our focused markets for unparalleled, continuous mission support. Apply knowledge of and expertise with acquisition management, program management, budget/finance principles and methodologies, modernization planning, and the Planning, Programming, Budgeting, and Executing (PPBE) process.