Senior Principal Scientist - Translational Muscle Biology UCBSenior Principal Scientist - Translational Muscle BiologyCambridge, MAThe candidate will bring hands-on scientific leadership to a matrixed team focused on identifying and building knowledge across pathobiological pathways and patient populations, including neuromuscular diseases related to nucleotide repeat expansions, genetic mutations, muscle atrophy, mitochondrial/lysosomal dysfunction, or inflammation. This is an opportunity for a scientific leader to advance portfolio projects and lead from the bench-exploring new biology and directly shaping the design, development, and execution of in vitro and in vivo models as well as cellular and biochemical assays for early drug discovery across multiple therapeutic programs and target discovery efforts.
Principal Audio/DSP Systems Engineer Analog DevicesPrincipal Audio/DSP Systems EngineerWilmington, MassachusettsPerform low-level implementation and optimization of signal processing and neural network kernels for fixed-point DSP and NPU instruction sets, maximizing utilization of MAC arrays, SIMD paths, and on-chip memory hierarchies. ADI combines analog, digital, AI, and software technologies into solutions that combat climate change, reliably connect humans and the world, and help drive advancements in automation and robotics, mobility, healthcare, energy and data centers.
Principal Data Scientist - Oncology Johnson & JohnsonPrincipal Data Scientist - OncologyCambridge, MA$117,000–$201,250 / yearAll Job Posting Locations: Cambridge, Massachusetts, United States of America, Raritan, New Jersey, United States of America, San Diego, California, United States of America, Spring House, Pennsylvania, United States of America, Titusville, New Jersey, United States of America. Work with Data Science & Digital Health colleagues, IT and DevOps teams to deploy and manage the graph database infrastructure, focusing on high availability, scalability, and recovery operations specifically geared toward Oncology R&D needs and applications.
Principal Engineer, Mixed Signal Designer Analog DevicesPrincipal Engineer, Mixed Signal DesignerWilmington, MassachusettsYour deep expertise will enable you to make critical technical tradeoffs across analog and digital domains, devise innovative solutions to complex problems, and provide technical leadership that influences ADI's technology direction and methodology. For positions requiring access to technical data, Analog Devices, Inc. may have to obtain export licensing approval from the U.S. Department of Commerce - Bureau of Industry and Security and/or the U.S. Department of State - Directorate of Defense Trade Controls.
Principal, Commercial Strategy Trinity PartnersPrincipal, Commercial StrategyWaltham, Massachusetts$188,000–$282,000 / yearThe Principal will also fulfill a highly strategic role in support of the firm’s success by: identifying innovative initiatives and implementing those; contributing as a strategic business partner to senior management; and developing short and long term goals and spearheading the implementation of related activities. Trinity’s salary bands account for a wide range of factors that are considered in making compensation decisions including but not limited to skill sets and market demand for skills; level of experience and training; specific qualifications, performance, time in role/company, geographic location, and other business and organizational needs.
Principal Mixed Signal Design Engineer, Technical Lead Analog DevicesPrincipal Mixed Signal Design Engineer, Technical LeadWilmington, MassachusettsThe candidate’s responsibilities will include system level product design, direct collaboration with tier 1 customers, leading internal design teams consisting of high speed, precision and digital design engineers and working closely with internal groups through the product development lifecycle including process, packaging and ESD. ADI combines analog, digital, AI, and software technologies into solutions that combat climate change, reliably connect humans and the world, and help drive advancements in automation and robotics, mobility, healthcare, energy and data centers.
Principal Motion Planning Engineer Pickle Robot CompanyPrincipal Motion Planning EngineerCharlestown, MASkills and Experience: 8+ years building robotics software, with a sustained record of designing and shipping complex systems as a senior individual contributor; deep graduate robotics/controls research experience counts toward this. Take on the hardest algorithmic problems in planning and control — sample-based planning (e.g., RRT), path and trajectory optimization, numerical/nonlinear optimization, and contact-aware control — and turn research prototypes into production systems.
Associate Principal, Analytics Trinity PartnersAssociate Principal, AnalyticsWaltham, New York$156,000–$234,000 / yearIn this role, you will oversee delivery of high-impact analytics engagements, serve as a key client contact, and guide teams in solving complex commercial business challenges across the product lifecycle with opportunity to contribute to account growth and revenue. Trinity’s salary bands account for a wide range of factors that are considered in making compensation decisions including but not limited to skill sets and market demand for skills; level of experience and training; specific qualifications, performance, time in role/company, geographic location, and other business and organizational needs.
Principal Product Security Cloud Engineer MondoPrincipal Product Security Cloud EngineerDanvers, Massachusetts$150,000–$170,000 / yearThis role is responsible for leading cloud and product security initiatives, ensuring secure design, compliance, and risk mitigation across connected medical device ecosystems. Develop and maintain product security documentation (threat models, risk assessments, SBOM, etc.).
Principal AI Accelerator Architect Lead Analog DevicesPrincipal AI Accelerator Architect LeadBoston, MassachusettsYou will lead the effort of translating product requirements, including functions and workloads, into end-to-end system architectures, producing well-defined specifications for IP blocks, processors, firmware, memory subsystems, and AI compute engines. Your responsibilities will include assessing and comparing various architectural approaches, conducting in-depth evaluations of selected computing modalities, and developing system models utilizing Synopsys Platform Architect to translate insights into precise implementation specifications.
Senior/Principal Product Security Engineer MondoSenior/Principal Product Security EngineerDanvers, Massachusetts$70–$85 / hourLead hands-on product security documentation and risk deliverables for regulated MedTech devices supporting FDA submission readiness. Develop and maintain product security plans and vulnerability reports (SOUP, MDS).
Principal Software Engineer MondoPrincipal Software EngineerWoburn, Massachusetts$65–$70 / hourNice-to-Haves:Experience with UI frameworks (Angular, React, Ember, Bootstrap). Apply now: Principal Software Engineer, location is Hybrid (Woburn, Westborough, MA or Cary, NC).
Principal Clinical Content- Physician - Uptodate, Physician Editor, Neurology Wolters KluwerPrincipal Clinical Content- Physician - Uptodate, Physician Editor, NeurologyWaltham, MARemote$173,500–$310,000 / yearUpToDate editors work closely with outside authors, section editors, editors-in-chief, and peer reviewers to ensure the material is accurate and free of bias. In the remaining 10 to 20% time, Physician Editors should continue patient care activities, using their clinical experience to help ensure the content of the program is maximally useful at the point of care.
Principal Systems Developer - DevSecOps InterSystemsPrincipal Systems Developer - DevSecOpsBoston, MassachusettsThis technical leadership role in the Database Platforms (DP) department will contribute to InterSystems’ next generation cloud-native database platform product as well as the InterSystems IRIS, InterSystems IRIS for Health and InterSystems Health Connect database platforms. The Platform Operations team needs an experienced developer or architect who can drive DevSecOps enhancements and maintenance including configuration, security, monitoring, licensing and upgrading for cloud with Kubernetes and traditional on-prem deployments on a range of supported platforms.
Principal Network Engineer Sun Life FinancialPrincipal Network EngineerWellesley Hills, MA$70,300–$105,500 / yearAdvanced proficiency in Infrastructure as Code (IaC) using Terraform or AWS CloudFormation, paired with experience utilizing Generative AI developer tools (e.g., Amazon Q, Amazon Bedrock, or AI coding assistants) to accelerate code generation, automate network compliance validation, and scale CI/CD network deployment pipelines. The ideal candidate will have strong experience designing, implementing, and supporting enterprise network infrastructure, with expertise in Cisco routing and switching technologies, WatchGuard firewalls, AWS networking services, Infrastructure as Code, and utilizing Generative Developer tools.
Senior Principal Engineer, Systems Design/Architecture Engineering Analog DevicesSenior Principal Engineer, Systems Design/Architecture EngineeringWilmington, MassachusettsLead the definition and architecture of multi-GHz digital communication products for test and instrumentation systems, establishing signal chain requirements, subsystem partitioning, signal processing, key interfaces, performance/power targets and process nodes. ADI combines analog, digital, AI, and software technologies into solutions that combat climate change, reliably connect humans and the world, and help drive advancements in automation and robotics, mobility, healthcare, energy and data centers.
Principal Mechanical Design Engineer RISE RoboticsPrincipal Mechanical Design EngineerSomerville, MAFounded in 2011 by graduates of MIT and RISD (Rhode Island School of Design), and backed by Engine Ventures, Techstars, Fortistar and Gates Corporation, RISE Robotics is leading the way to Zero Emission heavy machinery by providing the world’s most efficient and productive alternative to hydraulics. Proven technical aptitude and experience with electro-mechanical design and related manufacturing processes that might include: complex mechanical assemblies; rotating machinery; tolerance studies; design for assembly / manufacturing; EE and ME component and material selection; FMEA; design for life.
Principal Mixed-Signal/Analog Design Engineer - Power/ATE Analog DevicesPrincipal Mixed-Signal/Analog Design Engineer - Power/ATEWilmington, MassachusettsAs ADI expands into new products and market segments, the Instrumentation group is looking for a skilled Mixed-Signal/Analog IC Design Engineer based in either Wilmington, MA or Colorado Springs, CO who will be responsible for designing high performance mixed-signal ICs with companion DC/DC converters targeted at ATE power management markets. For positions requiring access to technical data, Analog Devices, Inc. may have to obtain export licensing approval from the U.S. Department of Commerce - Bureau of Industry and Security and/or the U.S. Department of State - Directorate of Defense Trade Controls.
Principal Analyst, Enterprise Architecture Forrester Research, Inc.Principal Analyst, Enterprise ArchitectureCambridge, MA$141,000–$229,000 / yearA Principal Analyst is expected to: Lead the Enterprise Solutions Architecture practice area, working across Forrester research teams, including the Technology Strategy and Executive Partner teams as well as Sales and Product to develop a complete research portfolio that drives customer delight and revenue. Job Requirements: At least 10 years of experience in a mix of roles as a director-level and above practitioner, enterprise architect, principal sales engineer, principal solutions architect, managing consultant, Director/Manager of Sales Engineering, or research analyst in an industry vertical or technology services.
Principal Data Links and Communications Engineer AstrionPrincipal Data Links and Communications EngineerBedford / Hanscom AFB, MassachusettsThis includes interface with Air Combat Command, Air Force Command and Control Integration Center, Joint Interoperability Test Command, Space and Naval Warfare Systems Command, and all levels of the organizations that develop and manage the C3 and encryption key distribution infrastructure for controlling a networked system, providing technical advice on C4 issues, including pre-launch conditioning and planning, aircraft-weapon pre- and post-release communications, and real-time targeting. This includes interfacing with the Federal, Department of Defense (DoD), United States Air Force (USAF), United States Army, and Joint communities to ensure the data link communications capability complies with the applicable Federal Aviation Administration, Defense Information Systems Agency (DISA), National Security Agency (NSA), Service Acquisition Executive, Joint Mission Planning System (JMPS), Damage Assessment and Casualty Report business and technical rules.