Principal Scientist, CDx IHC Development SystimmunePrincipal Scientist, CDx IHC DevelopmentRedmond, WAFull timeThis is a hands‑on scientific leadership role requiring strong collaboration with pathology, translational science, regulatory, clinical development, and external diagnostic partners to ensure successful CDx execution aligned with therapeutic timelines. Analytical Validation & Design Control Lead analytical validation strategy and execution for CDx IHC assays, including sensitivity, specificity, precision, accuracy, and robustness.
Principal Software Engineer - Growth (CoreAI) MicrosoftPrincipal Software Engineer - Growth (CoreAI)Redmond, WA$165,600–$296,400 / yearAt this level, impact comes from building repeatable systems and raising the engineering bar: better experiment quality, better telemetry, safer rollouts, and clearer business outcomes — delivered through pragmatic execution and deep technical judgment. There is a different range applicable to specific work locations, within the San Francisco Bay area and New York City metropolitan area, and the base pay range for this role in those locations is USD $220,800 - $331,200 per year.
Principal Product Manager- AI Integrity MicrosoftPrincipal Product Manager- AI IntegrityRedmond, WA$142,800–$274,800 / yearImprove abuse monitoring and detection systems that identify and mitigate real-world AI threats and misuse, including prompt injection, jailbreaks, data exfiltration, malicious tool calls, coordinated abuse, model exploitation and other novel vectors. There is a different range applicable to specific work locations, within the San Francisco Bay area and New York City metropolitan area, and the base pay range for this role in those locations is USD $188,000 - $304,200 per year.
Principal Hardware Engineer, AI Systems MicrosoftPrincipal Hardware Engineer, AI SystemsRedmond, WA$142,800–$274,800 / yearMasters Degree in Electrical Engineering, Computer Engineering, Mechanical Engineering, or related field AND 7+ years technical engineering experience OR Bachelors Degree in Electrical Engineering, Computer Engineering, Mechanical Engineering, or related field AND 8+ years technical engineering experience. To achieve this goal, the Cloud Hardware Systems Engineering (CHSE) team is instrumental in defining and delivering operational measures of success for hardware manufacturing, improving the planning process, quality, delivery, scale and sustainability related to Microsoft cloud hardware.
Senior Principal Technical Program Manager MicrosoftSenior Principal Technical Program ManagerRedmond, WA$165,600–$296,400 / yearCloud Infrastructure Automation and Optimization (CIAO) is the software team that delivers tools, automation, and AI to enable fast, predictable delivery of datacenter capacity, and safe, reliable, and efficient execution of the processes associated with the full life cycle of datacenter management and operations. There is a different range applicable to specific work locations, within the San Francisco Bay area and New York City metropolitan area, and the base pay range for this role in those locations is USD $220,800 - $331,200 per year.
Principal Applied Scientist - CoreAI MicrosoftPrincipal Applied Scientist - CoreAIRedmond, WA$142,800–$274,800 / yearBachelors Degree in Computer Science, Computational Linguistics, or related field AND 6+ years related experience (e.g., statistics, predictive analytics, research) OR Masters Degree in Computer Science, Computational Linguistics or related field AND 4+ years related experience (e.g., statistics, predictive analytics, research). There is a different range applicable to specific work locations, within the San Francisco Bay area and New York City metropolitan area, and the base pay range for this role in those locations is USD $188,000 - $304,200 per year.
Principal UX Researcher Microsoft CorpPrincipal UX ResearcherRedmond, WA$142,800–$274,800 / yearPreferred Qualifications: Doctorate in Human-Computer Interaction, Human Factors Engineering, Computer Science, Technical Communications, Information Science, Information Architecture, User Experience Design, Behavioral Science, Social Sciences, or related field AND 5+ years user experience research experience. Required Qualifications: Doctorate in Human-Computer Interaction, Human Factors Engineering, Computer Science, Technical Communications, Information Science, Information Architecture, User Experience Design, Behavioral Science, Social Sciences, or related field AND 3+ years User Experience Research experience.
Principal Service Engineer - Security Focused Microsoft CorpPrincipal Service Engineer - Security FocusedRedmond, WA$142,800–$274,800 / yearRequired/Minimum Qualifications: Bachelors Degree in Computer Science, Information Technology, Mechanical Engineering, Electrical Engineering, Aerospace Engineering, Data Science, Cybersecurity, or related field AND 6+ years technical experience in software engineering, network engineering, service engineering, systems engineering, or industrial controls OR equivalent experience. You will create and monitor action plans for telemetry data and drive analytics that improve the detection and troubleshooting of problems, building large-scale detection and monitoring in Kusto (Azure Data Explorer)/Microsoft Sentinel, Microsoft Defender for Cloud and other Big Data tools such as Spark, SQL, and delivering high-quality automation that removes manual toil.
NewPrincipal or Senior Quantum Engineer - Readout Design Microsoft CorpPrincipal or Senior Quantum Engineer - Readout DesignRedmond, WA$119,800–$234,700 / yearThere is a different range applicable to specific work locations, within the San Francisco Bay area and New York City metropolitan area, and the base pay range for this role in those locations is USD $160,200 - $261,000 per year. There is a different range applicable to specific work locations, within the San Francisco Bay area and New York City metropolitan area, and the base pay range for this role in those locations is USD $188,000 - $304,200 per year.
Principal Security Research Manager Microsoft CorpPrincipal Security Research ManagerRedmond, WA$142,800–$274,800 / yearThe role is ideal for engineers who can operate end to end: understand the workflow, design the benchmark, build the harness, implement validators and graders, run experiments, analyze quality and cost tradeoffs, connect results to production feedback, and help teams make evidence-based release decisions. Required Qualifications: Doctorate in Statistics, Mathematics, Computer Science, Computer Security, or related field AND 3+ years experience in software development lifecycle, large-scale computing, threat analysis or modeling, cybersecurity, vulnerability research, and/or anomaly detection.
Principal Software Engineer - Web Platform Privacy Microsoft CorpPrincipal Software Engineer - Web Platform PrivacyRedmond, WA$142,800–$274,800 / yearThere is a different range applicable to specific work locations, within the San Francisco Bay area and New York City metropolitan area, and the base pay range for this role in those locations is USD $188,000 - $304,200 per year. Starting January 26, 2026, Microsoft AI (MAI) employees who live within a 50- mile commute of a designated Microsoft office in the U.S. or 25-mile commute of a non-U.S., country-specific location are expected to work from the office at least four days per week.
Principal Product Manager, Ads Retail Lead Microsoft CorpPrincipal Product Manager, Ads Retail LeadRedmond, WA$142,800–$274,800 / yearYou will work at the intersection of advertiser needs, consumer engagement, data-driven insights, and platform innovation to create advertising products that help brands reach customers more effectively and achieve measurable business outcomes. There is a different range applicable to specific work locations, within the San Francisco Bay area and New York City metropolitan area, and the base pay range for this role in those locations is USD $188,000 - $304,200 per year.
Principal Hardware Security & Platform Engineer Microsoft CorpPrincipal Hardware Security & Platform EngineerRedmond, WA$142,800–$274,800 / yearThere is a different range applicable to specific work locations, within the San Francisco Bay area and New York City metropolitan area, and the base pay range for this role in those locations is USD $188,000 - $304,200 per year. Join the Systems Planning and Architecture (SPARC) team within Microsoft's Azure Hardware Systems and Infrastructure (AHSI) organization, the team behind Microsoft's expanding Cloud Infrastructure and for powering Microsoft's "Intelligent Cloud" mission.
Principal Software Engineer II - Next-Gen Data Transformations SnowflakePrincipal Software Engineer II - Next-Gen Data TransformationsBellevue, WashingtonDrive Technical Strategy for the AI Era: Provide technical leadership to senior management and multiple departments, influencing how Snowflake’s core compute fabric evolves to support the burgeoning Model Context Protocol (MCP), autonomous agent ecosystems and modern Python and Spark data processing workflows. Drive Customer Success through Direct Engagement: Partner with Snowflake’s most strategic customers and field engineering teams to translate massive-scale architectural challenges into core engine requirements, ensuring our processing primitives meet the real-world demands of the global Data Cloud.
Principal Product Manager - Ads Measurement MicrosoftPrincipal Product Manager - Ads MeasurementRedmond, WA$142,800–$274,800 / yearThere is a different range applicable to specific work locations, within the San Francisco Bay area and New York City metropolitan area, and the base pay range for this role in those locations is USD $188,000 - $304,200 per year. Starting January 26, 2026, Microsoft AI (MAI) employees who live within a 50- mile commute of a designated Microsoft office in the U.S. or 25-mile commute of a non-U.S., country-specific location are expected to work from the office at least four days per week.
Principal Software Engineering - AI Frameworks MicrosoftPrincipal Software Engineering - AI FrameworksRedmond, WA$142,800–$274,800 / yearThere is a different range applicable to specific work locations, within the San Francisco Bay area and New York City metropolitan area, and the base pay range for this role in those locations is USD $188,000 - $304,200 per year. Bachelors Degree in Computer Science or related technical field AND 6+ years technical engineering experience with coding in languages including, but not limited to, C, C++, C#, Java, JavaScript, or Python OR equivalent experience.
Principal Software Engineer - Responsible AI (CoreAI) MicrosoftPrincipal Software Engineer - Responsible AI (CoreAI)Redmond, WA$142,800–$274,800 / yearThere is a different range applicable to specific work locations, within the San Francisco Bay area and New York City metropolitan area, and the base pay range for this role in those locations is USD $188,000 - $304,200 per year. Bachelors Degree in Computer Science or related technical field AND 6+ years technical engineering experience with coding in languages including, but not limited to, C, C++, C#, Java, JavaScript, Go, or Python OR equivalent experience.
Principal Software Engineer I - Metadata SnowflakePrincipal Software Engineer I - MetadataBellevue, WashingtonWe look for low-ego individuals who thrive in dynamic and fast-moving environments and move with an experimental mindset — who rapidly test emerging capabilities to discover simpler, more powerful ways to deliver results. Work closely with our customers & partners, understand their use cases & needs, think strategically to seek the right problem to solve at the right time, and innovate with rigor.
Principal Product Manager - AI Security (CoreAI) MicrosoftPrincipal Product Manager - AI Security (CoreAI)Redmond, WA$142,800–$274,800 / yearThere is a different range applicable to specific work locations, within the San Francisco Bay area and New York City metropolitan area, and the base pay range for this role in those locations is USD $188,000 - $304,200 per year. This includes integrating AI security capabilities with Microsoft’s broader security stack - including Microsoft Defender, Entra, Purview, and Azure AI Foundry - to deliver a comprehensive security platform for AI systems.
Principal Technical Product Manager, Minecraft MicrosoftPrincipal Technical Product Manager, MinecraftRedmond, WA$142,800–$274,800 / yearLead regular ongoing syncs and organize technical summits between internal and external teams to align high-level technical direction, surface risks and dependencies, share knowledge, and build cross-team relationships. Implement strategy and own health of the China codebase by leading technical migrations, reducing tech debt, driving code integration, identifying areas for improvement and working closely with our co-dev partner to understand their needs.