Director, Computational Biology Ionis Pharmaceuticals IncDirector, Computational BiologyBoston, MA$157,542–$206,759 / yearWith multiple marketed medicines and a leading pipeline in neurology, cardiology and select areas of high patient needs, we continue to drive innovation in RNA therapies in addition to advancing new approaches in gene editing to provide greater value to patients and are well positioned financially to deliver on our strategic goals. Well-suited candidates will have a systems level approach to understanding biology that harmonizes multiple interacting functional inputs including transcriptional regulation, protein function and larger order (cellular and tissue) biochemical relationships.
Senior Scientist, Computational Biology - Contract Tessera Therapeutics IncSenior Scientist, Computational Biology - ContractSomerville, MA$74–$80 / hourHis group supports drug candidate programs through genotoxicity risk assessment, develops computational approaches to study gene writing biology, and builds scalable data and analysis infrastructure to support molecular assay design and knowledge mining. Broad knowledge of genome editing technologies and associated off-target discovery assays (i.e. WGS; targeted sequencing; GUIDE-seq, Digenome-seq discovery / verification; large and small structural variations and translation effects; NGS QC).
Associate Director, Discovery Biology Superluminal MedicinesAssociate Director, Discovery BiologyBoston, MassachusettsSignificant hands-on experience in cell-based assay development, execution and interpretation across a broad range of assays and platforms (functional, target engagement, kinetic, plate-based, flow cytometry, high content imaging). The Company’s platform aims to create candidate-ready compounds with unprecedented speed using a combination of deep biology, computational and medicinal chemistry, machine learning, and proprietary big data infrastructure.
Data Scientist Contractor, Computational Biology CAMP4 Therapeutics CorpData Scientist Contractor, Computational BiologyCambridge, MAKey Responsibilities: Process, analyze, visualize, and interpret next-generation sequencing (NGS) datasets, with an emphasis on bulk RNA-seq, scRNAseq, and long-read RNA sequencing, including Nanopore and PacBio sequencing data. CAMP4 is seeking a Data Science Contractor for a 6-month temporary contract assignment, specializing in Computational Biology, Bioinformatics, or Systems Biology, to support the processing, analysis, visualization, and interpretation of next-generation sequencing datasets.
Senior/Principal Scientist, Computational Biology Cellular IntelligenceSenior/Principal Scientist, Computational BiologyBoston, MassachusettsWe take a full-stack approach, generating perturbation data at over 1,000x the efficiency of conventional methods, capturing millions of time-resolved treatment combinations per experiment, and training large-scale models that generalize across contexts to enable rational protocol design for regenerative medicine, context-specific drug effect prediction, and systematic disease modeling. As a Senior Computational Biologist, your core job is to discover novel biological insight from rich biological data across transcriptomic datasets, including data from our own novel microfluidic-based assays and therapeutic programs, and to ground our AI and machine learning efforts in deep expertise in transcriptomics and biology.