Senior Scientist, Computational Biology - Contract Tessera TherapeuticsSenior Scientist, Computational Biology - ContractSomerville, MA$74–$80 / hourHis group supports drug candidate programs through genotoxicity risk assessment, develops computational approaches to study gene writing biology, and builds scalable data and analysis infrastructure to support molecular assay design and knowledge mining. Broad knowledge of genome editing technologies and associated off-target discovery assays (i.e. WGS; targeted sequencing; GUIDE-seq, Digenome-seq discovery / verification; large and small structural variations and translation effects; NGS QC).
Senior Scientist, Computational Biology - Contract Tessera Therapeutics IncSenior Scientist, Computational Biology - ContractSomerville, MA$74–$80 / hourHis group supports drug candidate programs through genotoxicity risk assessment, develops computational approaches to study gene writing biology, and builds scalable data and analysis infrastructure to support molecular assay design and knowledge mining. Broad knowledge of genome editing technologies and associated off-target discovery assays (i.e. WGS; targeted sequencing; GUIDE-seq, Digenome-seq discovery / verification; large and small structural variations and translation effects; NGS QC).
Data Scientist - Computational Biology Penfield Search PartnersData Scientist - Computational BiologyWaltham, MAThe ideal candidate has hands-on experience with RNA sequencing data, strong computational biology expertise, and enjoys collaborating closely with experimental scientists to generate biological insights that advance therapeutic discovery. This individual will support drug discovery research by processing, analyzing, visualizing, and interpreting next-generation sequencing (NGS) datasets, with a strong emphasis on transcriptomics and long-read sequencing technologies.
Scientist, Cellular & Molecular Biology - Lexington, MA DSMScientist, Cellular & Molecular Biology - Lexington, MALexington, MA$100,000–$125,000 / yearThe successful candidate will play a hands-on role in designing and executing cell-based assays, supporting preclinical and translational studies, and handling human clinical samples in a BSL 2 laboratory environment. Collaborate closely with cross-functional teams (Data Science, Regulatory Affairs, and Biotechnology) to integrate cellular data into broader study frameworks.
Scientist, Cellular & Molecular Biology - Lexington, MA DSM Nutritional Products Asia Pacific Pte LtdScientist, Cellular & Molecular Biology - Lexington, MALexington, MA$100,000–$125,000 / yearThe successful candidate will play a hands-on role in designing and executing cell-based assays, supporting preclinical and translational studies, and handling human clinical samples in a BSL 2 laboratory environment. Collaborate closely with cross-functional teams (Data Science, Regulatory Affairs, and Biotechnology) to integrate cellular data into broader study frameworks.
Scientist, Computational Biology Flagship Pioneering IncScientist, Computational BiologyCambridge, MA$115,000–$165,000 / yearThe successful candidate will be a driven, experienced scientist who is enthusiastic about developing state-of-the-art techniques to pioneer the detection of cellular dynamics from minimally invasive biospecimens. Strong hands-on experience analyzing mass spectrometry-based proteomics data is required; direct experience with raw mass spec data processing, QC, normalization, and feature extraction is strongly preferred.
Principal Scientist, ADCs Discovery Biology, Oncology Thematic Research Center Bristol-Myers Squibb CoPrincipal Scientist, ADCs Discovery Biology, Oncology Thematic Research CenterMA$156,180–$189,252 / yearThe scientists at this state-of-the-art research and development site in Cambridge focus on novel tumor intrinsic targets and pathways for tumors that are refractory to current Immuno-Oncology and Oncology therapies and implement our discovery platforms across all of our therapeutic areas of focus. Based on eligibility*, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day.
NewPostdoctoral Scientist – Gene Therapy Biodistribution & Molecular Biology (CNS) Eli Lilly and CompanyPostdoctoral Scientist – Gene Therapy Biodistribution & Molecular Biology (CNS)MassachusettsApply a broad toolkit of molecular and bioanalytical techniques, including: PCR-based approaches (PCR, qPCR, ddPCR, stem-loop PCR, vg/dg dose quantification) for vector genome and transcript quantification;ELISA and immunoassays for protein expression and biomarker analysis;LC–MS–based quantitative bioanalysis where applicable;Immunohistochemistry (IHC) and tissue-based spatial analyses to enable regional CNS characterization;Next-generation sequencing (NGS) methods to support vector tracking, expression profiling, or integration-related analyses. Our current groups include: Africa, Middle East, Central Asia (AMECA), Black Employees at Lilly (BE@Lilly), Chinese Culture Network (CCN), EnAble, Evolve, Lilly Indian Network (LIN), Organization of Latinx at Lilly (OLA), Pride (LGBTQ+ Allies), Veterans Leadership Network (VLN) and Women’s Initiative for Leading at Lilly (WILL).
NewPostdoctoral Scientist - Gene Therapy Biodistribution & Molecular Biology (Cns) Eli Lilly and CompanyPostdoctoral Scientist - Gene Therapy Biodistribution & Molecular Biology (Cns)Boston, MA$58,000–$123,200 / yearApply a broad toolkit of molecular and bioanalytical techniques, including: PCR-based approaches (PCR, qPCR, ddPCR, stem-loop PCR, vg/dg dose quantification) for vector genome and transcript quantification; ELISA and immunoassays for protein expression and biomarker analysis; LC-MS-based quantitative bioanalysis where applicable; Immunohistochemistry (IHC) and tissue-based spatial analyses to enable regional CNS characterization; Next-generation sequencing (NGS) methods to support vector tracking, expression profiling, or integration-related analyses. Our current groups include: Africa, Middle East, Central Asia (AMECA), Black Employees at Lilly (BE@Lilly), Chinese Culture Network (CCN), EnAble, Evolve, Lilly Indian Network (LIN), Organization of Latinx at Lilly (OLA), Pride (LGBTQ+ Allies), Veterans Leadership Network (VLN) and Women's Initiative for Leading at Lilly (WILL).
Postdoctoral Scientist - Gene Therapy Biodistribution & Molecular Biology (CNS) Eli Lilly and CoPostdoctoral Scientist - Gene Therapy Biodistribution & Molecular Biology (CNS)Boston, MA$58,000–$123,200 / yearApply a broad toolkit of molecular and bioanalytical techniques, including: PCR-based approaches (PCR, qPCR, ddPCR, stem-loop PCR, vg/dg dose quantification) for vector genome and transcript quantification; ELISA and immunoassays for protein expression and biomarker analysis; LC-MS-based quantitative bioanalysis where applicable; Immunohistochemistry (IHC) and tissue-based spatial analyses to enable regional CNS characterization; Next-generation sequencing (NGS) methods to support vector tracking, expression profiling, or integration-related analyses. Our current groups include: Africa, Middle East, Central Asia (AMECA), Black Employees at Lilly (BE@Lilly), Chinese Culture Network (CCN), EnAble, Evolve, Lilly Indian Network (LIN), Organization of Latinx at Lilly (OLA), Pride (LGBTQ+ Allies), Veterans Leadership Network (VLN) and Women's Initiative for Leading at Lilly (WILL).
Principal Scientist, Biology (Immunology) C4 Therapeutics IncPrincipal Scientist, Biology (Immunology)Watertown, MA$187,632–$207,383 / yearC4T's degrader medicines are designed to harness the body's natural protein recycling system to rapidly degrade disease-causing proteins, offering the potential to overcome drug resistance, drug undruggable targets and improve patient outcomes. The base pay range for this position at commencement of employment is expected to be between $187,632.00 and $207,383.00 annually; however, base pay offered may vary depending on multiple individualized factors, including job-related knowledge, skills, and experience.
Principal Scientist, Computational Biology Bristol-Myers Squibb CoPrincipal Scientist, Computational BiologyMARemote$166,770–$202,086 / yearIPS conducts applied computational research in areas that include genomic, structural and molecular informatics, computational and systems biology, patient selection and translational biomarker research, and broader fields including knowledge science, epidemiology and machine learning-across the full lifecycle of drug discovery and development and across all therapeutic areas at BMS. Hands on experience analyzing and integrating high-dimensional molecular datasets such as multi-omics (RNA-seq, ATAC-seq, proteomics, ChIP-seq/CUT&RUN), single cell profiling (CITE-seq, scATAC-seq, perturb-seq) and/or spatial profiling to derive novel biological insights.
Associate Scientist II Delivery Biology Alnylam Pharmaceuticals IncAssociate Scientist II Delivery BiologyCambridge, MA$67,600–$101,400 / yearThe successful candidate will play a key part in generating high-quality in vitro and ex vivo data to support delivery biology programs in a highly matrixed, cross-functional research environment. We are seeking a highly motivated Associate Scientist II in Delivery Biology to support our efforts focused on improving the cellular delivery of nucleic acid-based therapeutics.
Scientist CNS Biology Research Alnylam Pharmaceuticals IncScientist CNS Biology ResearchCambridge, MA$110,400–$165,600 / yearThorough understanding of relevant in vivo mammalian disease models strongly preferred, with experience in intracerebroventricular (ICV) injections, necropsy, behavioral analysis, ex vivo tissue processing, and downstream analysis including molecular and histological assessments. Working closely with a multidisciplinary team, the Scientist will be responsible for identifying and validating novel drug targets, championing early programs, and supporting programs as they advance through clinical stages.
Senior Principal Scientist - Translational Muscle Biology UCBSenior Principal Scientist - Translational Muscle BiologyCambridge, MAThe candidate will bring hands-on scientific leadership to a matrixed team focused on identifying and building knowledge across pathobiological pathways and patient populations, including neuromuscular diseases related to nucleotide repeat expansions, genetic mutations, muscle atrophy, mitochondrial/lysosomal dysfunction, or inflammation. This is an opportunity for a scientific leader to advance portfolio projects and lead from the bench-exploring new biology and directly shaping the design, development, and execution of in vitro and in vivo models as well as cellular and biochemical assays for early drug discovery across multiple therapeutic programs and target discovery efforts.
Senior Associate Scientist, In Vivo Pharmacology, Oncology Discovery Biology Bristol-Myers Squibb CoSenior Associate Scientist, In Vivo Pharmacology, Oncology Discovery BiologyMA$105,040–$127,287 / yearPosition Responsibilities: In the role as a Senior Associate Scientist within In Vivo Discovery Oncology, the ideal candidate will: Experience in conducting mouse in vivo pharmacology experiments, including but not limited to model development, tumor implantation, dosing via IV, IP, SC, IT, IM, and PO routes, tumor measurements, health monitoring, tissue sampling by tail vessel micro-sampling, cardiac puncture and tissue/tumor collection at necropsy including fixation, freezing and tissue disaggregation to support ex vivo analyses. Independently execute end-to-end flow cytometry workflows, encompassing panel design and establishment, multiparametric profiling of blood, tumor, and lymphoid tissues, downstream data analysis, and clear communication of results to cross-functional teams.
NewSenior Scientist Delivery Biology-Tissue Lead Alnylam Pharmaceuticals IncSenior Scientist Delivery Biology-Tissue LeadCambridge, MA$126,400–$189,600 / yearThe individual will need excellent collaboration and communication skills, connecting interdisciplinary team members from medicinal chemistry, core delivery technology group and targets team. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people.
Associate Scientist II Next Wave Biology Alnylam Pharmaceuticals IncAssociate Scientist II Next Wave BiologyMA$67,600–$101,400 / yearResponsibilities will include designing and executing studies evaluating small interfering RNAs (siRNAs) in rodent models in vivo and in cellular models in vitro and conducting downstream molecular and biochemical-based assays, including transcript and protein quantitation. Demonstrate keen knowledge of experimental design, underlying scientific principles, and the ability to rigorously and independently analyze results, propose future directions, solve challenging problems and generate clear reports.
Senior Associate Scientist Biology Alnylam Pharmaceuticals IncSenior Associate Scientist BiologyCambridge, MA$80,000–$120,000 / yearResponsibilities will include designing, developing, and executing studies in rodent obesity models using small interfering RNAs (siRNAs) and conducting the associated in vitro molecular-based assays such as qPCR, western blots, and ELISAs. The successful candidate will support early development of potential therapeutic programs as part of a multidisciplinary team and be involved in the discovery of RNAi compounds for a indications related to obesity, diabetes and other rare metabolic conditions.
NewAssociate Product Development Scientist Ajinomoto Cambrooke, Inc.Associate Product Development ScientistAyer, MassachusettsFull timeWorking Conditions / Physical Requirements: WORKING CONDITIONS: This position works in a food manufacturing environment and requires the ability to adhere to all GMP, Food Safety, workplace safety and security policies including wearing required personal protective equipment, as well hair net, beard net, etc. Strong collaboration with product development, regulatory affairs, quality, operations, and commercial team members to ensure development and commercialization of medical nutrition products of highest quality and sensory attributes that meet the needs of the patient population.