NewSr. Oncology Clinical Research Associate JobotSr. Oncology Clinical Research AssociateBoston, MA$120,000–$140,000 / yearInformation collected and processed as part of your Jobot candidate profile, and any job applications, resumes, or other information you choose to submit is subject to Jobot's Privacy Policy, as well as the Jobot California Worker Privacy Notice and Jobot Notice Regarding Automated Employment Decision Tools which are available at jobot.com/legal. Conducts site visits including but not limited to Pre-study visits, initiation visits, interim monitoring visits, close-out visits to ensure compliance with protocols, Sponsor SOPs, ICH/GCP and all applicable regulations.
NewResearch Senior Scientist, Cheminformatics Takeda PharmaceuticalResearch Senior Scientist, CheminformaticsBoston, MA$137,000–$215,270 / yearSee Takeda Pharmaceutical Terms of Use at https://www.takeda.com/terms-of-use/ and Privacy Policy at https://www.takeda.com/privacy-notice/ and SonicJobs Privacy Policy at https://www.sonicjobs.com/us/privacy-policy and Terms of Use at https://www.sonicjobs.com/us/terms-conditions. Implement and execute innovative computational methodologies and tools such as AI-based drug discovery, generative chemistry, synthesizable chemical space exploration, DNA Encoded Library (DEL) data analysis and DEL/ML application.
NewSr. CRA (Oncology) Sponsor side! JobotSr. CRA (Oncology) Sponsor side!Boston, MA$125,000–$140,000 / yearInformation collected and processed as part of your Jobot candidate profile, and any job applications, resumes, or other information you choose to submit is subject to Jobot's Privacy Policy, as well as the Jobot California Worker Privacy Notice and Jobot Notice Regarding Automated Employment Decision Tools which are available at jobot.com/legal. By applying for this job, you agree to receive calls, AI-generated calls, text messages, or emails from Jobot, and/or its agents and contracted partners.
NewSenior Financial Analyst Berkeley Research Group, LLCSenior Financial AnalystBoston, MA$80,000–$135,000 / yearComprised of experienced, hands-on professionals that are results-oriented and data-driven, the market leading BRG Corporate Finance practice collaborates as partners with management teams and sponsors to focus on strategic options that maximize value for stakeholders. The BRG Corporate Finance practice specializes in providing strategic, operational, and financial advice to private equity firms, management teams, boards of directors, investors, hedge funds, and other lenders or companies that are either underperforming or in transition.
NewSenior Manufacturing Engineer RJS AssociatesSenior Manufacturing EngineerBillerica, MAFull timeManufacturing Engineer will monitor production and testing, assist in troubleshooting manufacturing issues, and drive continuous improvement efforts throughout the process. Manufacturing Engineer your primary responsibility will be to take ownership of one or more product lines and manage that product line’s manufacturing process from beginning to end.
NewSenior Associate - Corporate Finance - Turnaround & Restructuring Berkeley Research Group, LLCSenior Associate - Corporate Finance - Turnaround & RestructuringBoston, MA$80,000–$135,000 / yearThe BRG Corporate Finance practice specializes in providing strategic, operational, and financial advice to private equity firms, management teams, boards of directors, investors, hedge funds, and other lenders or companies that are either underperforming or in transition. Together, they bring a diversity of real-world experience, data, and human and artificial intelligence, to economics, disputes, and investigations; corporate finance; and performance improvement services that address the most complex challenges facing organizations across the globe.
NewTax Senior (Remote) JobotTax Senior (Remote)Boston, MARemote$110,000–$140,000 / yearInformation collected and processed as part of your Jobot candidate profile, and any job applications, resumes, or other information you choose to submit is subject to Jobot's Privacy Policy, as well as the Jobot California Worker Privacy Notice and Jobot Notice Regarding Automated Employment Decision Tools which are available at jobot.com/legal. We believe that putting your employees first is not only the right thing to do, but it also gives us the competitive edge to ensure our clients have an excellent experience!
NewSenior Accountant Vaco LLCSenior AccountantBoston, MA$100,000–$120,000Determining compensation for this role (and others) at Vaco by Highspring depends upon a wide array of factors including but not limited to: the individual’s skill sets, experience and training; licensure and certification requirements; office location and other geographic considerations; other business and organizational needs. Determining compensation for this role (and others) at Vaco/Highspring depends upon a wide array of factors including but not limited to the individual’s skill sets, experience and training, licensure and certifications, office location and other geographic considerations, as well as other business and organizational needs.
NewSenior Billing Specialist Vaco LLCSenior Billing SpecialistBoston, MA$25–$35Determining compensation for this role (and others) at Vaco by Highspring depends upon a wide array of factors including but not limited to: the individual’s skill sets, experience and training; licensure and certification requirements; office location and other geographic considerations; other business and organizational needs. Determining compensation for this role (and others) at Vaco/Highspring depends upon a wide array of factors including but not limited to the individual’s skill sets, experience and training, licensure and certifications, office location and other geographic considerations, as well as other business and organizational needs.
NewSenior Tax Manager Kforce Inc.Senior Tax ManagerWaltham, MA$150,000–$180,000Summary: The Senior Tax Manager is an important leadership role responsible for overseeing the preparation and review of complex tax returns for partnerships (with a focus on real estate), S-corporations, individuals, and trusts. You will guide operational excellence, help grow the tax practice, mentor the tax team, and provide strategic solutions to deliver quality client service.
NewSenior Director, AIRx Discovery Biology Lead Takeda PharmaceuticalSenior Director, AIRx Discovery Biology LeadBoston, MA$212,000–$333,190 / yearThe AIRx Discovery Biology Lead combines deep scientific expertise with the agility to thrive in an externalized, AI-powered operating model — leveraging biological depth and pragmatism to direct and integrate biology at speed, while role modeling new ways of working in Discovery Automation & Robotics (DAR) group. Responsibilities include directing CRO partners with precision and accountability to generate high-quality, interpretable data that feeds into AI-powered DMTA cycles, and connecting experimental biology to translational strategy and clinical outcomes.
NewTax Senior Kforce Inc.Tax SeniorConcord, MA$115,000–$135,000Employee pay is based on factors like relevant education, qualifications, certifications, experience, skills, seniority, location, performance, union contract and business needs. By clicking “Apply Today” you agree to receive calls, AI-generated calls, text messages or emails from Kforce and its affiliates, and service providers.
NewSenior Sales Executive - Accounting & Finance Vaco LLCSenior Sales Executive - Accounting & FinanceBoston, MA$50,000–$80,000Determining compensation for this role (and others) at Vaco by Highspring depends upon a wide array of factors including but not limited to: the individual’s skill sets, experience and training; licensure and certification requirements; office location and other geographic considerations; other business and organizational needs. Determining compensation for this role (and others) at Vaco/Highspring depends upon a wide array of factors including but not limited to the individual’s skill sets, experience and training, licensure and certifications, office location and other geographic considerations, as well as other business and organizational needs.
NewSenior Director, AIRx Medicinal Chemistry Takeda PharmaceuticalSenior Director, AIRx Medicinal ChemistryBoston, MA$212,000–$333,190 / yearSee Takeda Pharmaceutical Terms of Use at https://www.takeda.com/terms-of-use/ and Privacy Policy at https://www.takeda.com/privacy-notice/ and SonicJobs Privacy Policy at https://www.sonicjobs.com/us/privacy-policy and Terms of Use at https://www.sonicjobs.com/us/terms-conditions. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job.
Sr. Tax Accountant Continental ResourcesSr. Tax AccountantBedford, MA$110,000–$130,000 / yearFull timeSupport the external CPA firm with income tax extensions and estimated tax payments, including providing required data, reviewing calculations, coordinating approvals, and ensuring timely filing and payment. Partner cross-functionally with accounting, finance, operations, billing, credit, and other departments to improve processes, streamline workflows, and support business needs.
NewSenior Director, AIRx Computational Chemistry Takeda PharmaceuticalSenior Director, AIRx Computational ChemistryBoston, MA$212,000–$333,190 / yearThis role drives in silico molecular design, leverages predictive models, and applies generative chemistry to power rapid DMTA cycles — directly enabling the speed and precision that define the AIRx incubator In AIRx, computational chemistry is a first-order decision-making function — generative proposals from this role directly shape what gets synthesized, what gets deprioritized, and ultimately what reaches the clinic. See Takeda Pharmaceutical Terms of Use at https://www.takeda.com/terms-of-use/ and Privacy Policy at https://www.takeda.com/privacy-notice/ and SonicJobs Privacy Policy at https://www.sonicjobs.com/us/privacy-policy and Terms of Use at https://www.sonicjobs.com/us/terms-conditions.
NewSenior Manufacturing Engineer Poly6Senior Manufacturing EngineerBurlington, MA$105,000–$160,000Create, oversee, and maintain detailed process SOP documentation, including work instructions, process flow diagrams, and technical reports, using tools like Microsoft Office Suite and ERP systems (e.g., Oracle). We deliver high-performance products that meet the rigorous demands of quality, durability, and precision required for next-generation turbine engines while helping reduce greenhouse gas emissions.
NewSystems Engineer, Senior DCS CorporationSystems Engineer, SeniorBedford, MA$90,220–$145,000 / yearThe Aerospace Management Systems Division programs, develops, delivers, and sustains air traffic management, CNS/ATM avionics expertise, and weather sensing and forecast capabilities, enabling military, civil, allied, and Foreign Military Sales customers to achieve their mission. Develop and maintain system architectures, interface definitions, and Model-Based Systems Engineering (MBSE) artifacts supporting Air Traffic Control (ATC), Command & Control (C2), communications, networking, tactical data links, and radio systems.
NewGeneral/Interdisciplinary Engineer, Senior - Secret DCS CorporationGeneral/Interdisciplinary Engineer, Senior - SecretBedford, MA$90,220–$170,000 / yearConduct systems architectural analyses to include system design/design feasibility and state-of-the-art assessment to Produce architectures, document planned and existing systems, determine deficiencies, develop alternatives, recommend solutions, and support development of a plan to implement the chosen solution per acquisition and sustainment system engineering processes. Analysis of Alternatives (AoA), Systems Engineering Plan (SEP)…), systems review and analysis with written reporting, briefing, and artifact development as required for all of the technical specialty areas defined in this section; and the planning and execution of all necessary technical reviews, assessments, and interchange meetings (e.g.
NewProgram Manager, Senior - TS DCS CorporationProgram Manager, Senior - TSBedford, MA$90,220–$188,000 / yearCommand, Control, Communications, and Battle Management (C3BM) has been tasked with delivering an integrated Department of the Air Force (DAF) Battle Network providing resilient decision advantage and enabling the USAF, USSF, Joint, and Coalition Force to win against the pacing challenge. C3BM’s main efforts are Architecture and Systems Engineering (ASE), Operational Response Team (ORT), and multiple mission integration teams such as Air, Maritime, and multiple acquisitions consisting of both the Advanced Battle Management System (ABMS) and Space.
NewClinical Research Nurse II, Oncology IconmaClinical Research Nurse II, OncologyBoston, MA$70.02–$72.19 / hourCoordinates with clinical research coordinators and collaborates with staff within respective disease groups and with outside organizations in the completion of clinical research trials. Position requires tact and diplomacy to successfully motivate/educate subjects and staff, and knowledge of research regulations and research compliance requirements, including Protection of Human Subjects.
NewSenior Director, Immunology and Translation CSL BehringSenior Director, Immunology and TranslationWaltham, MA$302,000–$350,000You will bring end-to-end experience from early ideation through first-in-disease and will partner closely with cross-functional teams including discovery research, translational medicine, clinical development, and business development to shape and advance CSL Behring's immunology pipeline. We use three strategic scientific platforms of plasma fractionation, recombinant protein technology, and cell and gene therapy to support continued innovation and continually refine ways in which products can address unmet medical needs and help patients lead full lives.
NewSenior Engineer Constellation EnergySenior EngineerBrighton, MA$138,600–$154,000Has completed assigned skills and knowledge development training (applicable Advanced Engineering, EPRI, and Constellation University training or industry provided training) to develop expert level of knowledge in designated areas. Now integrated with Calpine, our portfolio includes 55 gigawatts of capacity from nuclear, natural gas, geothermal, hydro, wind and solar facilities, with the generating capacity to power the equivalent of 27 million homes.
NewSubstation Senior Civil/Structural Engineer LeidosSubstation Senior Civil/Structural EngineerMarlborough, MA$92,300–$166,850If you received an email purporting to be from Leidos that asks for payment-related information or any other personal information (e.g., about you or your previous employer), and you are concerned about its legitimacy, please make us aware immediately by emailing us at LeidosCareersFraud@leidos.com. Additional factors considered in extending an offer include (but are not limited to) responsibilities of the job, education, experience, knowledge, skills, and abilities, as well as internal equity, alignment with market data, applicable bargaining agreement (if any), or other law.
NewSenior Construction Project Manager *US AMR-Jones Lang LaSalle Americas, Inc.Senior Construction Project ManagerWaltham, MA$120,000–$140,000What this job involves: The Senior Construction Project Manager role involves leading end-to-end project delivery by developing and executing project strategies, budgets, and schedules that align with both JLL and client objectives. Whether you’ve got deep experience in commercial real estate, skilled trades or technology, or you’re looking to apply your relevant experience to a new industry, join our team as we help shape a brighter way forward.
NewSenior Director, Search & Evaluation Late TA Lead, Immunology CSL BehringSenior Director, Search & Evaluation Late TA Lead, ImmunologyWaltham, MA$263,000–$328,000We use three strategic scientific platforms of plasma fractionation, recombinant protein technology, and cell and gene therapy to support continued innovation and continually refine ways in which products can address unmet medical needs and help patients lead full lives. Focused on serving patients’ needs by using the latest technologies, we discover, develop and deliver innovative therapies for people living with conditions in the immunology, hematology, cardiovascular and metabolic, respiratory, and transplant therapeutic areas.
NewSenior Civil/Structural Engineer LeidosSenior Civil/Structural EngineerBoston, MA$73,450–$132,775We are seeking a Licensed Senior Civil/Structural Engineer with 5+ years of experience within the utility industry working directly for a utility or consulting company, doing design engineering and reviews. If you received an email purporting to be from Leidos that asks for payment-related information or any other personal information (e.g., about you or your previous employer), and you are concerned about its legitimacy, please make us aware immediately by emailing us at LeidosCareersFraud@leidos.com.
NewSr. Administrative Associate - Pulmonary Medicine Boston Children's HospitalSr. Administrative Associate - Pulmonary MedicineBoston, MARemote$20.63–$31.46Transcribe and type from recorded dictation, shorthand, or rough draft correspondence, reports, manuscripts, charts, and other materials for clinical, administrative, or research purposes, including highly complex and/or confidential financial/business documents. Obtain and organize planning information, prepare or order publicity materials and advertisements, reserve event location(s), and secure necessary supplies, equipment, and services.
NewFMS Program Manager, Senior - Secret DCS CorporationFMS Program Manager, Senior - SecretBedford, MA$60,467–$100,000 / yearThe Air Force Program Execution Office for PEO Electronic Systems (AFPEO/HB) has the collective Air Force Materiel Command (AFMC) mission responsibility to manage and execute the modernization, development, testing, production, fielding, and sustainment of the PEO Command and Control portfolio, which includes over 130 programs for the United States Air Force (USAF) and foreign allies. Serve as a representative of the program office to international customers, including the partner nation Ministry of Defense (MOD), Office of Defense Cooperation (ODC), and Air Force stakeholders, and respond to programmatic questions related to acquisition, cost, schedule, and performance.
Senior Tax Professional (CPA Firm) ProPivotalSenior Tax Professional (CPA Firm)Waltham, MAThe new hirewill be responsible for leading and managing a team of tax professionals, preparing and reviewing complex federal, state, and local tax returns for individuals, businesses, and organizations. Provide tax planning and advisory services to clients, including reviewing and analyzing financial statements, accounting records, and relevant documentation.
NewSenior Power Electronics Engineer DraperSenior Power Electronics EngineerCambridge, MAA Senior Power Electronics Engineer designs, specifies, develops, and tests power system architectures and requirements for a wide array of applications, including miniature power conversion and management circuitry, distributed power architectures, radiation hardened designs, novel battery management circuitry, small motor controllers, switched-mode power conversion and precision feedback systems. • Knowledge in at least one of the following areas: Isolated and non-Isolated dc/dc power conversion; rectification; inversion; battery management systems; motor controller design; system-level power distribution design; system/board level grounding/shielding and EMC design techniques.
NewSenior Digital Electronics Design Engineer DraperSenior Digital Electronics Design EngineerCambridge, MAAs a senior member of the Harsh Environments Electronics Group, you will help shape digital hardware architectures and lead electronics development activities by applying sound engineering and project management principles. As a Senior Digital Engineer, you will work closely with multi-disciplinary teams designing, developing, and verifying high reliability digital electronics for use in a wide array of applications.
NewSenior AI Agent Engineer GE VernovaSenior AI Agent EngineerCambridge, MA$113,200–$188,800GE Vernova Inc. or its affiliates (collectively or individually, “GE Vernova”) sponsor certain employee benefit plans or programs GE Vernova reserves the right to terminate, amend, suspend, replace, or modify its benefit plans and programs at any time and for any reason, in its sole discretion. 3+ years of experience designing and building GenAI apps that allow users to experience AI use cases supporting features like agent orchestration, multi-step reasoning, prompt engineering, RAG integration, and model selection.
Senior Mechanical Engineer - Product Development Michael Page USASenior Mechanical Engineer - Product DevelopmentBillerica, MA$130,000–$160,000 / yearFull timeKnown for tackling complex clinical challenges, the company invests heavily in R&D, values engineering rigor, and fosters a hands‑on, collaborative culture where technical excellence is recognized and rewarded. As the Senior Mechanical Engineer, Product Development, you will lead the design and development of innovative electromechanical medical products used in high impact clinical applications.
NewSenior Scientist, Cell Biology Alnylam PharmaceuticalsSenior Scientist, Cell BiologyCambridge, MA$126,400–$189,600 / yearLearn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: https://www.alnylam.com/careersAboutAlnylamWe are the leader in RNAi therapeutics- a revolutionaryapproach with the potential to transform the lives of people with rare and common diseases. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity).Alnylam's robust Total Rewards package is designed to support your overall health and well-being.
NewSenior GNC Systems Engineer DraperSenior GNC Systems EngineerCambridge, MAWorking in a dynamic team environment developing state-of-the-art weapon/GN&C systems will provide exposure to a wide range of advanced technologies as well as afford opportunities for increased leadership/impact on the development of new war-fighter capability. The Hypersonic and Advanced Weapons group at Draper is seeking a Senior Guidance, Navigation, and Control (GNC) Systems Engineer to work within and lead multi-disciplinary teams to design next-generation weapon system concepts for the war fighter.
Program Manager, Senior DCS CorporationProgram Manager, SeniorBedford, MA$90,220–$180,000 / yearEPASS support is required to execute the major GNS programs in support of the C2ISR Division, to include AF DCGS Network Infrastructure Transformation (NIT), Extended Tether Program (ETP), and Global Command and Control System – Air Force Infrastructure (GCCS-AF (I)). The C2ISR Division provides worldwide life cycle support across the spectrum of the C2ISR capabilities-based enterprise; including supply, distribution, materiel management, acquisition, system engineering and maintenance, financial planning and budgeting, security, flight test, and contracting functions.
Senior Staff Engineer, R&D Tooling - Plastics - Nashua, NH Michael Page USASenior Staff Engineer, R&D Tooling - Plastics - Nashua, NHNashua, NH$120,000–$135,000 / yearFull timeThe culture values collaboration, continuous improvement and practical problem‑solving, offering engineers the opportunity to work closely with manufacturing, suppliers and R&D teams in a hands‑on, technically challenging setting. Reporting directly into the Engineering Manager, you will be responsible for the following: Lead the technical development and ongoing improvement of R&D tooling across multiple manufacturing processes.
Senior Project Manager - Public and Private Construction Michael Page USASenior Project Manager - Public and Private ConstructionBoston, MA$120,000–$180,000 / yearFull timeSpecializing in both Public & Private projects in RI & Boston - including Higher Education, Healthcare, Fitness, Banking, Corporate, Civic, Aviation, Historic preservation, Affordable Housing, and MBTA projects - $3M-$40M. Commercial General Contractor looking for a tenured Project Manager with experience successfully running Public & Private projects to join their team!
NewSenior Construction Project Manager US AMR-Jones Lang LaSalle Americas, Inc.Senior Construction Project ManagerWaltham, MAWhat this job involves: The Senior Construction Project Manager role involves leading end-to-end project delivery by developing and executing project strategies, budgets, and schedules that align with both JLL and client objectives. Whether you've got deep experience in commercial real estate, skilled trades or technology, or you're looking to apply your relevant experience to a new industry, join our team as we help shape a brighter way forward.
NewClinical Trial Manager IconmaClinical Trial ManagerBoston, MA$26.16–$28.34 / hourAdvise RSP policy owner/committee chair on policy style, writing, programming; collaboration with subject matter experts; alignment of policy directives, procedural job aids, and committee direction. Identify available resources, including needed mentoring, partnerships, for example, SRG, scientific writing core, CCRO, biostats core, IRB, budget development].
NewSenior Mixed Signal Electronics Design Engineer DraperSenior Mixed Signal Electronics Design EngineerCambridge, MAThe Draper team is chartered with supporting the Nation’s most challenging problems by 1) providing an iterative and agile approach to innovative and creative technical solutions delivered at the speed of mission and 2) driving leading edge technology development efforts to support future mission needs. The Tailored Systems Business Area within Electronics Program Office directorate delivers first-of-a-kind field-ready microelectronics solutions in support of National Security missions.
NewSoftware Development Engineer JobotSoftware Development EngineerBoston, MA$65–$80 / hourDevelopers at this level are building greater independence, taking ownership of small to medium-sized work items, and strengthening their core engineering skills across multiple application layers, including user interfaces, services, APIs, and data. Our teams include professionals across software engineering, product development, clinical informatics, research, and healthcare technology who share a commitment to reducing complexity and improving outcomes for patients and providers.
NewSenior Sensor Electronics Engineer DraperSenior Sensor Electronics EngineerBoston, MAA Senior Sensor Electronics Engineer designs, specifies, develops, and tests analog electronics for a wide array of applications, such as analog front ends, signal conditioning, analog-to-digital conversion, radiation hardened designs, motor controllers, low noise power conditioning for precision instrumentation, and precision feedback systems. The engineer develops the architecture, designs these circuits, performs simulations, implements the physical layout, verifies and tests designs.
Senior Research Coordinator - Human Nutrition Research Center on Aging Tufts UniversitySenior Research Coordinator - Human Nutrition Research Center on AgingBoston, MAThe Senior Research Coordinator works with Principal Investigator and other research staff to coordinate and execute the NIH-funded study entitled: The Impact of Biological Mechanisms of Aging on Response Variability to Resistance Training in Older Adults (BRIO). They assist with various aspects of study set-up, study participant visits, and assorted tasks during the active study, including randomization, outcome measures, and interventions, as well as data collection, management, and quality control.
Research Associate / Sr. Research Associate - Automation & Screening ManusResearch Associate / Sr. Research Associate - Automation & ScreeningWaltham, MAManus is seeking a Research Associate (RA) or Senior Research Associate (SRA) to support high-throughput screening (HTS) and laboratory automation workflows to identify engineered microbial strains with enhanced performance. Manus works across industries and value chains to accelerate the transition to BioAlternatives – better performing and more sustainable versions of complex molecules traditionally sourced from plants, animals, or fossil fuels.
NewSenior Clinical Research Coordinator - Urology Mass General BrighamSenior Clinical Research Coordinator - UrologyBoston, MassachusettsResearch Assistant to join their team who will work very independently under minimal supervision to enroll eligible patients in clinical research protocols and manage all aspects of data collection and submission for multiple cancer studies. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success.
NewResearch Associate / Senior Research Associate- In Vitro Pharmacology Biotech Experience Required Manifold Bio IncResearch Associate / Senior Research Associate- In Vitro Pharmacology Biotech Experience RequiredBoston, MA$70,000–$108,000 / yearManifold Bio is a platform biotechnology company pioneering AI-guided protein design and massively multiplexed in vivo screening to unlock tissue-targeted medicines and organism-scale models of living systems. In this role, you will support in vitro shuttled-oligonucleotide screening and disease programs through execution of essential assays that drive selection and Go/No Go decisions to progress molecules from screens into disease programs.