Monte Rosa Therapeutics IncDirector / Associate Director - Toxicology Monte Rosa Therapeutics IncDirector / Associate Director - ToxicologyBoston, MAThis is an individual contributor role by designing, conducting or overseeing studies, analyze/interpret, and report in vitro, ex vivo, and in vivo non-GLP (or GLP studies conducted at CROs) nonclinical pharmacology, PK/PD, and/or toxicology studies, in collaboration with study monitors and other scientists. The discovery toxicologist interacts directly with multidisciplinary teams including biology, medicinal chemistry, DMPK, clinical science, and outside CROs in research and/or development projects to move discovery candidates into development.
Monte Rosa Therapeutics, IncNewDirector / Associate Director – Toxicology Monte Rosa Therapeutics, IncDirector / Associate Director – ToxicologyBoston, MassachusettsThis is an individual contributor role by designing, conducting or overseeing studies, analyze/interpret, and report in vitro, ex vivo, and in vivo non-GLP (or GLP studies conducted at CROs) nonclinical pharmacology, PK/PD, and/or toxicology studies, in collaboration with study monitors and other scientists. The discovery toxicologist interacts directly with multidisciplinary teams including biology, medicinal chemistry, DMPK, clinical science, and outside CRO’s in research and/or development projects to move discovery candidates into development.
Sanofi GroupNewHead of Toxicology Innovation Sanofi GroupHead of Toxicology InnovationCambridge, MA$232,500–$335,833.33 / yearChampion the development and qualification of novel in vitro models — including organoids, microphysiological systems (MPS/organ-on-chip), and advanced cell culture platforms — to investigate mechanisms of toxicity and understand human relevance. With direct oversight of laboratory operations in France and the United States, and digital capabilities in Germany, you will lead a truly global, multidisciplinary team united by a shared commitment to scientific excellence and patient safety.
Prime Medicine IncSenior Scientist, Safety Assessment Prime Medicine IncSenior Scientist, Safety AssessmentCambridge, MA$145,000–$177,000 / yearD. in toxicology or a related field with 6+ years of pharma/biotech experience in nonclinical safety assessment, or an M.S. in toxicology or a related field with 10+ years of experience in nonclinical safety assessment, the ability to work independently, provide domain expertise and leadership, as well as cross-functionally in a fast-paced, matrixed environment with a positive, flexible attitude. Position Overview We are seeking an enthusiastic, self-motivated Senior Scientist to join the Nonclinical Development group, supporting the nonclinical safety assessment function for IND-enabling programs across Prime Medicines pipeline.
Alnylam Pharmaceuticals IncScientist Investigative Sciences Alnylam Pharmaceuticals IncScientist Investigative SciencesMADevelop and implement cell-based and biochemical assays to assess receptor binding signaling endocytosis and trafficking to support novel ligand candidate derisking and selection. Expertise in characterizing receptor-ligand interactions and downstream cell signaling or cellular function readouts is highly desired.
CEDENTSenior Scientist, Bioanalytical Sciences CEDENTSenior Scientist, Bioanalytical SciencesCambridge, MADevelop and oversee ligand-binding immunoassays (ELISA, MSD, Luminex or similar platforms) for the detection of translated proteins and anti-drug or anti-protein antibodies, including screening, confirmatory, and neutralizing antibody assays in accordance with regulatory guidance. You will be a subject matter expert in nucleic acid and protein bioanalysis, working to generate critical data that informs decision-making across preclinical and clinical development.
DuPont de Nemours IncProduct Stewardship & Regulatory Analyst DuPont de Nemours IncProduct Stewardship & Regulatory AnalystMarlborough, MA$56,000–$88,000 / yearEach individual's pay is based on a variety of factors, including their role and the associated pay range for that role, their geographic location (i.e., country, state, metropolitan area), as well as their skills, experience, education and certifications, and performance. At Qnity, we're more than a global leader in materials and solutions for advanced electronics and high-tech industries - we're a tight-knit team that is motivated by new possibilities, and always up for a challenge.
Deep OriginNewVP/SVP of Drug Discovery Deep OriginVP/SVP of Drug DiscoveryBoston, MAThis individual will serve as a key scientific and operational leader inside the company, partnering closely with computational scientists, experimental scientists (own lab), platform teams, translational biology, external collaborators, and executive leadership to prioritize programs, guide strategic decisions, and accelerate pipeline execution. This is a critical executive leadership role for a hands-on scientific leader who has spent significant time navigating the realities of drug discovery and development — someone who understands not only what can work scientifically, but what actually translates into successful therapeutic programs.
Rhythm PharmaceuticalsDirector, Nonclinical Development Rhythm PharmaceuticalsDirector, Nonclinical DevelopmentBoston, MAFull timePropose, design, and oversee nonclinical toxicology, DMPK, and ADME studies at external CROs (GLP and non‑GLP), providing scientific oversight of protocols, execution, data interpretation, and final reports, and managing CRO relationships, timelines, and budgets. Serve as the nonclinical development lead on cross‑functional program teams, providing scientific input to development strategy, risk assessment, and decision‑making across multiple programs.