Associate Scientist

Job Description:
Associate Scientist is responsible for the development of robust, efficient, scalable and transferable lentiviral vector (LVV) manufacturing for early and late-stage cell therapy programs, for both ex-vivo and in-vivo delivery approaches. This role will have the opportunity to directly support current pipeline programs in process development and CMC activities, as well as drive groundbreaking technology development of next generation vector processes.
Responsibilities:

• Complete routine PD-grade viral vector production operations at both bench scale and pilot scale, including but not limited to media preparation, culture initiation, seed train maintenance and bioreactor operations, to support process development studies and material generation for pre-clinical programs.
• Perform viral vector production experiments to assess the impact of process changes and new technologies to drive critical innovation projects for next generation LVV production processes.
• Develop experimental plans, interpret scientific results, and provide statistical analysis where appropriate.
• Perform general laboratory tasks, including maintenance of equipment and inventory.
• Support technology transfer activities to manufacturing partners as an upstream SME.
• Generate, manage, evaluate, and maintain critical data in an organized way, including lab notebook maintenance with good documentation practices.

Requirements:

• Experience with bioreactors, control software, and process analytical technology is strongly preferred.
• General knowledge of process development and pharmaceutical manufacturing is helpful. Experience with scale-up and pilot plant operations is a plus.
• Experience with vector process development and manufacturing is preferred.
• Independently motivated, detail oriented, and good problem-solving ability.
• Ability to work effectively within a cross-functional team dynamic and able to handle, adjust, and show independent drive to complete deliverables in a fast-paced environment.
• Outstanding interpersonal and communication skills, effective, efficient, and organized.
• To be considered for this role, you must have the following:
• BS/MS in Bioengineering, Chemical engineering, Biology, Cell Biology or related biological sciences with 2+ years (MS), or 4+ years (BS) of proven experience in biotechnology or pharmaceutical industry.
• Strong understanding of cell biology and hands-on experience with mammalian cell culture is required.