Life Science Research Professional 2 (1 Year Fixed-Term)

We are seeking a highly skilled and motivated Research Specialist (Life Science Research Professional 2) for a 1 year fixed-term to join our laboratory focused on understanding resilience and plasticity during mammalian embryogenesis. Our work combines in vivo lineage tracing, single-cell genomics, and genetic perturbation approaches to study how embryos recover from developmental perturbations.

A central component of this role will be the generation and maintenance of transgenic mouse lines. We are looking for someone with deep technical expertise and hands-on experience across all stages of mouse transgenesis.

Key Responsibilities

• Perform all aspects of mouse transgenesis, including:

o Superovulation and timed matings

o Embryo isolation (zygote and blastocyst stages)

o Microinjection or electroporation of embryos

o Blastocyst handling, culture, and manipulation

o Surgical transfer of embryos into pseudopregnant recipients

• Establish and expand transgenic founder lines
• Genotype and validate transgenic animals
• Maintain detailed experimental records and ensure high reproducibility
• Collaborate closely with lab members on experimental design and execution
• Contribute to optimizing and developing new transgenic approaches
• • Other duties may also be assigned

What We Offer

• A collaborative and intellectually stimulating research environment
• Opportunities to contribute to cutting-edge studies in developmental biology
• Competitive salary and benefits package
• This position is offered as a one-year fixed-term appointment, with strong potential for extension based on performance and continued funding.

How to Apply

In addition to applying through the online application portal, please email Dr. Bowling directly (sarah.bowling@stanford.edu) to submit a CV and a brief statement outlining your experience with mouse transgenesis and interest in the position.

The job duties listed are typical examples of work performed by positions in this job classification and are not designed to contain or be interpreted as a comprehensive inventory of all duties, tasks, and responsibilities. Specific duties and responsibilities may vary depending on department or program needs without changing the general nature and scope of the job or level of responsibility. Employees may also perform other duties as assigned.

The expected pay range for this position is $85,376 to $99,581 per annum.

Stanford University provides pay ranges representing its good faith estimate of the salary or hourly wage the university reasonably expects to pay for a position upon hire. The pay offered to a selected candidate will be determined based on factors such as (but not limited to) the scope and responsibilities of the position, the qualifications of the selected candidate, departmental budget availability, internal equity, geographic location and external market pay for comparable jobs. At Stanford University, base pay represents only one aspect of the comprehensive rewards package.

The Cardinal at Work website (https://cardinalatwork.stanford.edu/benefits-rewards) provides detailed information on Stanford's extensive range of benefits and rewards offered to employees. Specifics about the rewards package for this position may be discussed during the hiring process.

Consistent with its obligations under the law, the University will provide reasonable accommodations to applicants and employees with disabilities. Applicants requiring a reasonable accommodation for any part of the application or hiring process should contact Stanford University Human Resources at stanfordelr@stanford.edu. For all other inquiries, please submit a contact form.

Stanford is an equal employment opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law. Stanford welcomes applications from all who would bring additional dimensions to the University''s research mission.

DESIRED QUALIFICATIONS:

• Bachelor's or Master's degree in Biology or a related field (PhD preferred but not required)
• Experience with CRISPR/Cas9 genome editing in embryos
• Familiarity with generating knock-in/knockout models
• Experience managing mouse colonies and transgenic workflows
• Background in developmental biology or genetics
• Must be comfortable working with mice
• Extensive hands-on experience in mouse transgenesis
• Demonstrated proficiency in:

o Superovulation and embryo collection

o Micromanipulation of embryos (injection and/or electroporation)

o Embryo culture and blastocyst handling

o Survival surgery for embryo transfer into pseudopregnant females

• Strong understanding of mouse reproductive biology and embryology
• Excellent surgical skills and attention to detail
• Ability to work independently and troubleshoot complex protocols

EDUCATION & EXPERIENCE (REQUIRED): Bachelor''s degree in related scientific field and two years of relevant work experience; or Master's degree in a related scientific field.

KNOWLEDGE, SKILLS AND ABILITIES (REQUIRED):

• Comprehensive understanding of scientific principles.
• General computer skills and ability to quickly learn and master computer programs, databases, and scientific applications.
• Strong analytical skills and excellent judgment.
• Ability to maintain detailed records of experiments and outcomes.
• Ability to work under deadlines with general guidance is essential.
• Excellent organizational skills and demonstrated ability to accurately complete detailed work.

PHYSICAL REQUIREMENTS*:

• Frequently stand, walk, twist, bend, stoop, squat, grasp lightly, use fine manipulation, grasp forcefully, perform desk-based computer tasks, use telephone, write by hand, lift, carry, push and pull objects weighing over 40 pounds.
• Occasionally sit, kneel, crawl, reach and work above shoulders, sort and file paperwork or parts.
• Rarely climb, scrub, sweep, mop, chop and mix or operate hand and foot controls.
• Must have correctible vision to perform duties of the job.
• Ability to bend, squat, kneel, stand, reach above shoulder level, and move on hard surfaces for up to eight hours.
• Ability to lift heavy objects weighing up to 50 pounds.
• Ability to work in a dusty, dirty, and odorous environment.
• Position may require repetitive motion.
• Add or subtract physical requirements based on the requirements of your specific job. (remove this statement for posting)
• • Consistent with its obligations under the law, the University will provide reasonable accommodation to any employee with a disability who requires accommodation to perform the essential functions of his or her job.

WORKING CONDITIONS:

• May require working in close proximity to blood borne pathogens.
• May require work in an environment where animals are used for teaching and research.
• Position may at times require the employee to work with or be in areas where hazardous materials and/or infectious diseases are present.
• Employee must perform tasks that require the use of personal protective equipment, such as safety glasses and shoes, protective clothing and gloves, and possibly a respirator.
• May require extended or unusual work hours based on research requirements and business needs.

Additional Information

• Schedule: Full-time
• Job Code: 4952
• Employee Status: Fixed-Term
• Grade: G
• Requisition ID: 109064
• Work Arrangement : On Site