Job Description
Organization Overview
Researchers in the Laboratory of Genetically Encoded Small Molecules are working on projects related to the human microbiome, bacterial small molecules, and host-microbial interactions. The lab s research is focused on identifying bacterial genes, pathways, and molecules that influence host-cellular functions and developing these host-microbial interactions into novel treatments for human disease. To this end, we focus on three major areas of research: 1) high throughput screening of bacterial metabolites and genes to identify effector functions, 2) mouse models of inflammatory and metabolic diseases, and 3) in vivo validation of bacterial metabolites and genes in human cohorts.
Overview
The Postdoctoral Associate will use methods from molecular biology, organic chemistry, and microbiology to access bioactive natural products and their respective biosynthetic gene clusters from the soil. Will be responsible for using a range of techniques, including molecular biology, tissue culture, animal work (mouse), and chemistry.
Responsibilities
Responsibilities include:
- Design and execute independent and collaborative research projects.
- Maintain strong organizational practices, attention to detail, and accurate research
- Communicate effectively and work both independently and collaboratively
- Engage in scientific writing and dissemination activities, including opportunities to lead first-authored manuscripts and contribute to collaborative publications and literature reviews
- Perform related duties & responsibilities as assigned/requested
Qualifications
REQUIRED QUALIFICATIONS:
- PhD in chemistry, biochemistry, microbiology, biology, or a related field
- Ability to independently conduct untargeted metabolomics studies and/or phylogenetic analyses of microbial communities in microbiome samples.
- Strong organization skills, attention to detail, and ability to maintain accurate records
- Excellent communication skills and the ability to work both independently and as part of a collaborative team in a fast-paced research environment
PREFERRED QUALIFICATIONS:
- Experience in multi-step natural product synthesis, medicinal chemistry, small molecule library development, compound characterization, and/or structure activity relationship optimization
- Experience in preparative and analytical chromatography and structural analysis of organic molecules
- Experience in peptide synthesis
- Experience with metabolite discovery and characterization
The Rockefeller University is an equal opportunity employer - veterans/individuals with disabilities. Qualified applicants will receive consideration for employment without regard to characteristics protected by applicable local, state or federal law, including but not limited to disability and protected veteran status.
The salary of the finalist selected for this role will be set based on various factors, including but not limited to organizational budgets, qualifications, experience, education, licenses, specialty, and training. The hiring range provided represents The Rockefeller University s good faith and reasonable estimate of the range of possible compensation at the time of posting.
Compensation Range: Min
USD $72,100.00/Yr.
Compensation Range: Max
USD $72,100.00/Yr.
Numbers & Facts
| Location | New York, NY |
| Industry | Education |
| Company Size | 2,500 to 4,999 employees |
| Year Founded | 1901 |
| Website | http://www.rockefeller.edu/ |
About Company
Founded by John D. Rockefeller, the Rockefeller Institute for Medical Research was incorporated on June 14, 1901. It was the first institution in the United States devoted solely to biomedical research--to understanding the underlying causes of disease. Today, renamed Rockefeller University, it is one of the foremost research centers in the world, contributing to 23 Nobel Prizes as well as numerous other awards. Rockefeller University Community
Rockefeller University researchers achieved many of the last century's seminal advances in the biomedical sciences, including:
The university's laboratory-based organizational structure "without walls" and pared-down layers of administration do away with the schools and academic departments that too often separate scientists. "This approach fosters a tremendously rich soup of interdisciplinary research and collaboration," says Rockefeller professor and Nobel laureate Günter Blobel. Acclaimed scientists
In its history, Rockefeller has been associated with 23 Nobel laureates and 19 Lasker Award recipients. Five faculty members have been named MacArthur Fellows and 12 have garnered the National Medal of Science, the highest science award given by the United States. And, 33 Rockefeller faculty are elected members of the National Academy of Sciences. Partnerships with other leading institutions
Rockefeller has close ties with neighboring Weill Medical College of Cornell University, New York-Presbyterian Hospital and Memorial Sloan-Kettering Cancer Center. Additional academic partnerships with the Courant Institute of New York University and Bard College provide students with a rich array of training opportunities. Rockefeller forges collaborations with biotech and pharmaceutical companies as needed to speed research findings into development to improve patient care.Clinical research hospital
In 1910, Rockefeller scientists founded the nation's first hospital devoted exclusively to experimental medicine. The Rockefeller University Hospital's only patients are participants in clinical trials building on basic research findings from Rockefeller labs. This "allows the university to maintain an unbroken spectrum of research, from basic to clinical," says Joshua Lederberg, Nobel laureate and Rockefeller president emeritus. Unburdened by constraints of standard patient care, the hospital is a vital component of Rockefeller's commitment to accelerating basic research findings on their route from bench to bedside for the diagnosis, treatment and prevention of disease. Studies are under way on AIDS/ HIV, obesity, hepatitis C and addictive diseases. More than science
Artistic and intellectual activity flourishes on Rockefeller's campus. The verdant grounds, situated on Manhattan's Upper East Side, boast a world-class art collection. The university regularly hosts events designed to explore the intuitive connection between science and the arts.Weekly and monthly recital series grace the university's spectacular auditorium, and a variety of exhibits regularly take shape on campus -currently including sculpture on temporary exhibition from New York's Museum of Modern Art. Select graduate student body
A class of Ph.D. and M.D.-Ph.D. students from across the United States and the world works closely with international faculty in a rigorous, highly personalized program of graduate study and research. The university offers graduate students access and opportunities to work with leading scientists, as well as full financial support and affordable on- and off-campus housing. University budget
Funding the research studies of The Rockefeller University's scientists are the National Institutes of Health and other government agencies, Howard Hughes Medical Institute, private gifts and endowment income.
- 71 heads of laboratories
- 200 research and clinical scientists
- 350 postdoctoral investigators
- 1,050 support staff
- 150 Ph.D. students
- 50 M.D.-Ph.D. students
- 887 alumni
- biochemistry, structural biology and chemistry
- molecular, cell and developmental biology
- immunology, virology and microbiology
- medical sciences and human genetics
- neuroscience
- physics and mathematical biology
Rockefeller University researchers achieved many of the last century's seminal advances in the biomedical sciences, including:
- Discovering that DNA is the basic material of heredity (1944)
- Determining that cancer can be caused by a virus (1911)
- Confirming the connection between cholesterol and heart disease (1950s)
- Developing methadone maintenance for people addicted to heroin (1960s)
- Developing the AIDS "cocktail" drug therapy (1990s)
The university's laboratory-based organizational structure "without walls" and pared-down layers of administration do away with the schools and academic departments that too often separate scientists. "This approach fosters a tremendously rich soup of interdisciplinary research and collaboration," says Rockefeller professor and Nobel laureate Günter Blobel. Acclaimed scientists
In its history, Rockefeller has been associated with 23 Nobel laureates and 19 Lasker Award recipients. Five faculty members have been named MacArthur Fellows and 12 have garnered the National Medal of Science, the highest science award given by the United States. And, 33 Rockefeller faculty are elected members of the National Academy of Sciences. Partnerships with other leading institutions
Rockefeller has close ties with neighboring Weill Medical College of Cornell University, New York-Presbyterian Hospital and Memorial Sloan-Kettering Cancer Center. Additional academic partnerships with the Courant Institute of New York University and Bard College provide students with a rich array of training opportunities. Rockefeller forges collaborations with biotech and pharmaceutical companies as needed to speed research findings into development to improve patient care.Clinical research hospital
In 1910, Rockefeller scientists founded the nation's first hospital devoted exclusively to experimental medicine. The Rockefeller University Hospital's only patients are participants in clinical trials building on basic research findings from Rockefeller labs. This "allows the university to maintain an unbroken spectrum of research, from basic to clinical," says Joshua Lederberg, Nobel laureate and Rockefeller president emeritus. Unburdened by constraints of standard patient care, the hospital is a vital component of Rockefeller's commitment to accelerating basic research findings on their route from bench to bedside for the diagnosis, treatment and prevention of disease. Studies are under way on AIDS/ HIV, obesity, hepatitis C and addictive diseases. More than science
Artistic and intellectual activity flourishes on Rockefeller's campus. The verdant grounds, situated on Manhattan's Upper East Side, boast a world-class art collection. The university regularly hosts events designed to explore the intuitive connection between science and the arts.Weekly and monthly recital series grace the university's spectacular auditorium, and a variety of exhibits regularly take shape on campus -currently including sculpture on temporary exhibition from New York's Museum of Modern Art. Select graduate student body
A class of Ph.D. and M.D.-Ph.D. students from across the United States and the world works closely with international faculty in a rigorous, highly personalized program of graduate study and research. The university offers graduate students access and opportunities to work with leading scientists, as well as full financial support and affordable on- and off-campus housing. University budget
Funding the research studies of The Rockefeller University's scientists are the National Institutes of Health and other government agencies, Howard Hughes Medical Institute, private gifts and endowment income.
Skills
- Analysis Skillsunmatched
- Biochemistryunmatched
- Biologyunmatched
- Chemistryunmatched
- Chromatographic Assayunmatched
- Communication Skillsunmatched
- Detail Orientedunmatched
- Disease Treatmentunmatched
- Geneticsunmatched
- High-Throughput Screening (HTS)unmatched
- Human Diseasesunmatched
- Inflammatory Diseasesunmatched
- Metabolic Disordersunmatched
- Microbiologyunmatched
- Molecular Biologyunmatched
- Organic Chemistryunmatched
- Organizational Skillsunmatched
- Publicationsunmatched
- Record Keepingunmatched
- Research Laboratoryunmatched
- Small Moleculesunmatched
- Team Playerunmatched
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