Principal Investigator (MD/DO)

Job Title: Principal Investigator (MD/DO)
Location: Cleveland, OH
Work Model: Onsite – onsite

We are seeking a US board certified MD/DO to work as a Principal Investigator overseeing clinical trials in Cleveland, OH. The role involves providing medical oversight, ensuring participant safety, and collaborating with study teams and sponsors. The ideal candidate will have experience in clinical research and hold an active, unrestricted Ohio medical license. This full-time, onsite position offers an opportunity to contribute to innovative medical research and patient-centered studies. If you are committed to advancing healthcare through clinical investigation, this could be an excellent opportunity for you.

Responsibilities
• Provide medical oversight and clinical leadership for assigned clinical trials, ensuring patient safety and data quality.
• Serve as the study physician, reviewing participant eligibility and providing medical oversight for screening outcomes.
• Review adverse events (AEs), serious adverse events (SAEs), and participant safety trends.
• Perform or oversee study-specific medical assessments, including histories, physical exams, and endpoint assessments.
• Offer clinical guidance and oversight to Sub-Investigators, Clinical Research Coordinators, RNs, and site staff.
• Collaborate with study sponsors, CROs, IRBs, and company leadership throughout each trial.
• Participate in site initiation visits, monitoring visits, close-out activities, and other study meetings.
• Review clinical data such as laboratory results, ECGs, vital signs, and other assessments.

Requirements
• MD or DO with a background in Internal Medicine, Family Medicine, or a Specialist.
• Active, unrestricted Ohio medical license.
• Prior clinical research experience as a Principal Investigator, Sub-Investigator, or other clinical research physician.
• Strong clinical judgment and commitment to participant safety.
• Interest in clinical research and advancing medical innovation.
• Board certification.
• DEA registration, if required by study protocols.

System One, and its subsidiaries including Mountain Ltd., are leaders in delivering outsourced services and workforce solutions across North America. We help clients get work done more efficiently and economically, without compromising quality. System One not only serves as a valued partner for our clients, but we offer eligible employees health and welfare benefits coverage options including medical, dental, vision, spending accounts, life insurance, voluntary plans, as well as participation in a 401(k) plan.

System One is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, age, national origin, disability, family care or medical leave status, genetic information, veteran status, marital status, or any other characteristic protected by applicable federal, state, or local law.

#LI-EL1
Ref: #568-Clinical