Research Technologist II

Job Summary and Responsibilities

As a Research Tech, you will perform standard laboratory procedures with some independence, under the general supervision of a PI or Research Technician. Your contributions are vital for efficient lab operations.

Every day you will execute experimental protocols, collect/record data, and maintain lab equipment. You may also perform complex procedures and provide guidance to students.

To be successful in this role, you will possess a strong foundation in lab techniques, meticulous attention to detail, and work effectively independently and collaboratively. Reliability, safety adherence, and a willingness to learn are key. Other primary responsibilities include:

• Receive process and manage biospecimens-including tumor tissue cerebrospinal fluid (CSF) and blood-in compliance with CLIA-regulated protocols
• Isolate cell-free DNA from CSF and extract genomic DNA from tumor tissue and peripheral blood
• Isolate circulating cells from CSF and perform tissue dissociation for downstream applications
• Prepare single-cell RNA sequencing libraries using the 10x Genomics platform from tumor and CSF-derived cells
• Generate DNA sequencing libraries from tumor tissue blood and cell-free DNA
• Maintain rigorous accurate documentation of experimental workflows in accordance with established protocols and regulatory standards
• Contribute to a collaborative research environment through participation in lab meetings seminars and journal clubs
• Keeps accurate records of studies conducted with minimal supervision.
• Performs basic data analysis and processing as required by senior laboratory personnel.
• Creates, maintains, and updates lab's internal procedure manuals.

The Ivy Brain Tumor Center is a pioneering non-profit clinical research program dedicated to developing transformative therapies for patients with aggressive brain tumors. As a global leader in early-phase neuro-oncology trials the Center hosts the largest portfolio of Phase 0 studies for brain tumors worldwide. Our multidisciplinary team integrates clinical care translational science and precision medicine to accelerate the identification and development of first-in-class therapies.

We are seeking a highly motivated Research Tech II to join our translational neuro-oncology research team. This role is ideal for an individual with strong laboratory experience who is capable of independently executing complex experimental workflows. The successful candidate will play a key role in advancing innovative liquid biopsy platforms to study pharmacogenomic response tumor evolution and disease progression.

Job Requirements

Required

• Bachelor's degree in biological sciences or a related field
• Two (2) years prior experience in ar research, clinical, or other scientific environment
• Prior laboratory research experience with demonstrated proficiency in cell culture molecular biology techniques (e.g. PCR qPCR) and/or sequencing library preparation
• Strong analytical and problem-solving skills with the ability to learn and execute new techniques independently
• Excellent attention to detail organization and time management
• Strong written and verbal communication skills

Preferred

• Four (4) years of prior experience in a research, clinical, or other scientific environment
• Background in cell biology neuroscience or oncology
• Familiarity with CLIA-regulated workflows and liquid biopsy methodologies
• Experience with single-cell RNA sequencing and next-generation sequencing platforms
• Additional Information: Two to three letters of recommendation may be requested

Where You'll Work

Hello Humankindness: Join a Legacy of Healing at Saint Joseph's Hospital and Medical Center (SJHMC)

Ready to make a real difference? Join SJHMC in Phoenix AZ., a 571-bed nonprofit founded by the Sisters of Mercy over 125 years ago. We're more than a hospital; we're a global destination for life-changing care, embracing patients with humankindness.

Here, your calling will flourish. We're not just a workplace; we're a community dedicated to a mission of service.

Leaders in Specialized Care:

• Barrow Neurological Institute (BNI): A world-renowned center for groundbreaking neurological research and innovative treatments.
• Norton Thoracic Institute (NTI): A national leader in advanced thoracic care with pioneering surgical techniques.
• Level I Trauma Center: One of Arizona's busiest ERs, providing immediate, comprehensive care for critically injured patients 24/7.

Why SJHMC?

• Culture of Excellence & Well-being: We care for our people, fostering professional and personal growth.
• Community & Collaboration: Be part of a network committed to global health and well-being.
• Join a Legacy, Shape a Future: Over 20% of our patients travel internationally for our specialized care.

This is an invitation to join a family of dedicated professionals at the forefront of medical innovation, united by the power of humankindness.