Scientific - Research Associate-Scientific
Job Title: Research Associate Scientific
Location: Cambridge Crossings, Cambridge, MA
Work Schedule: 100% onsite, Monday Friday, normal business hours
Parking: Candidates must be agreeable with the $20/day parking fee at Cambridge Crossings
MUST HAVE LIST
" Bachelor's degree in biological sciences, engineering, chemistry, physics, math, computer sciences, or related fields
" 3+ years of hands-on experience in a laboratory
" Preferred: Prior experience with spatial technologies (e.g., Phenocycler/CODEX, COMET, Visium, CosMx, Xenium, or equivalent platforms), genomics (e.g., scRNA-seq, Illumina Next Generation Sequencing), or histology workflows (e.g., multiplex IF/IHC/ISH on autostainer) training will be provided for the right candidate
" Quick learner with an openness to adopting new technologies
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Position Summary
The Research Associate scientist will be a key member of the Translational Development Team in Cambridge, MA, utilizing high-dimensional spatial and genomic profiling tools to address translational knowledge gaps across our development pipelines. The ideal candidate brings hands-on experience in one or more of these areas, strong foundational lab skills, and the ability to work independently and collaboratively to meet project goals.________________________________________
Position Responsibilities
" Operate, maintain, and troubleshoot spatial profiling instruments (Phenocycler Fusion, Visium, and related platforms)
" Prepare samples and reagents, including validation and slide preparation
" Support genomic and histological assay workflows
" Maintain accurate records, manage reagent/sample inventory, and perform routine data transfers
" Assist in the development and optimization of new spatial technology reagents and protocols
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Qualifications & Experience
Required
" Bachelor's degree in biological sciences, engineering, chemistry, physics, math, computer sciences, or related fields
" 3+ years of hands-on laboratory experience
" Quick learner with genuine openness to new technologies and methodologies
" Excellent hands-on technical and organizational skills, with strong attention to detail and quality
" Effective and timely communication skills with both peers and senior leadership
" Demonstrated ability to meet project goals and timelines
" Experience in a collaborative team environment
Must have/Preferred Spatial & Advanced Profiling (Requirement)
" Hands-on experience with spatial transcriptomics or proteomics platforms, including one or more of: Phenocycler/CODEX (Akoya), COMET (Lunaphore), Visium (10x Genomics), CosMx (NanoString/Bruker), Xenium (10x Genomics), or comparable technologies
" Familiarity with spatial assay workflows: antibody panel design, staining optimization, and image acquisition/analysis
" Experience with single-cell RNA sequencing (scRNA-seq) or bulk RNA/DNA sequencing using Illumina platforms
" Familiarity with library preparation, sequencing workflows, DV200 test
Preferred Histology/Pathology, Cell Culture (Secondary Preference)
" Experience with multiplex immunofluorescence (mIF), IHC, or ISH workflows, particularly on automated autostainer platforms (e.g., Leica Bond, Ventana)
" Basic proficiency in mammalian culture and standard laboratory assays including single cell cloning, CRISPR-Cas9, protein immunoblot and flow cytometry (4+ channels).
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Working Conditions
" The position is primarily in a laboratory environment and may involve working with hazardous materials, including human tissue and blood samples
" Adherence to all relevant safety protocols and Client laboratory standards is required
EEO:
Mindlance is an Equal Opportunity Employer and does not discriminate in employment on the basis of Minority/Gender/Disability/Religion/LGBTQI/Age/Veterans.