Scientist I, High-Throughput Biology

Eikon Therapeutics, Inc.
  • Millbrae, CA
  • $123,000–$149,100 Per Year
  • Autofill and Review
8 days ago

Job Description

Position

As a member of the High-Throughput Biology Team, you will play a key role in pioneering drug discovery screening assays using Eikon's proprietary live-cell, single-molecule high-throughput super-resolution microscopy platform. You will work at the intersection of biology, automation engineering, and computational science to design, execute and deliver scalable, reproducible, decision-enabling biological data that drives progress across drug discovery portfolios.

About You

You are a highly motivated, rigorous, and interdisciplinary scientist who enjoys developing, optimizing, and validating live-cell imaging-based assays at scale to push the frontier of drug discovery. You are creative, data-driven, and skilled at problem solving in a fast-paced, dynamic, and matrixed environment. You are conscientious, detail-oriented, and organized, and are committed to delivering high-quality and actionable data in a timely manner. You are an effective communicator and teammate who is eager to learn and collaborate with people from diverse scientific backgrounds.

What You'll Do

  • Design, execute, and analyze robust and reproducible experiments to optimize, validate, and scale up live-cell imaging-based assays for high-throughput screening using Eikon's proprietary super-resolution microscopy platform.
  • Collaborate with computational biologists and software engineers to apply state-of-the-art computational and statistical methods including machine-learning to analyze large datasets.
  • Summarize and deliver timely, high-quality and actionable data to drive project team decisions across drug discovery portfolios.
  • Exercise good scientific judgment and provide data-driven recommendations to project teams.
  • Maintain organized and comprehensive electronic records of experiments, results, and protocols in adherence to company standards and regulatory requirements.
  • Work closely with the High-Throughput Biology Operations Team to transfer optimized processes into productionized operations workflows with well-documented standard operating procedures.
  • Collaborate and communicate across a diverse team of biologists, chemists, and engineers.
  • Contribute to the growth and training of junior scientists.

Qualifications

  • Ph.D. or Master's plus 10 years of relevant experience or Bachelor's degree plus 12 years of relevant experience in Biology, Bioengineering, Biotechnology, or related field.
  • Proficiency in mammalian cell culture with sterile technique.
  • Proficiency in laboratory techniques and equipment relevant to molecular and cellular biological research.
  • Demonstrated experience in systematic optimization and validation of biological assays.
  • Strong analytical and troubleshooting skills with novel assay technologies.
  • Working experience in quantitative fluorescence microscopy and/or super-resolution microscopy.
  • Working experience with relevant quantitative and/or statistical analysis using common software tools (e.g., Microsoft Suite, GraphPad Prism, etc.).
  • Working experience with one or more high-level programming languages (e.g., Python, MATLAB or R) to perform large dataset analysis and visualization.
  • Excellent communication skills, with the ability to convey scientific concepts effectively.
  • Collaborative mindset with the capacity to work effectively within multidisciplinary teams.
  • Proactive and adaptable to evolving research priorities and challenges.
  • Working experience in protein dynamics using single-molecule microscopy is preferred.
  • Working experience with high-throughput instrumentation and automation systems is preferred.

At Eikon, employee compensation also includes bonus and equity compensation, in addition to several generous benefit programs, including:

  • 401k plan with company matching
  • Medical (premiums covered by Eikon at 95%), dental and vision insurance (premiums covered by Eikon at 100%)
  • Mental health and wellness benefits
  • Weeklong summer and winter holiday shutdowns
  • Generous paid time off and holiday policies
  • Life/AD&D Insurance (premiums covered by Eikon at 100%) and optional supplemental employee-paid life/AD&D policies
  • Enhanced parental leave benefit
  • Daily subsidized lunch program when on-site

The expected salary range for this role is $123,000 to $149,100 depending on skills, competency, and the market demand for your expertise.

Numbers & Facts

LocationMillbrae, CA
Salary$123,000–$149,100 Per Year

Skills

  • Analysis Skillsunmatched
  • Assaysunmatched
  • Automation Engineeringunmatched
  • Automation Systemsunmatched
  • Bioengineeringunmatched
  • Biological Assayunmatched
  • Biologyunmatched
  • Biotech and Pharmaceuticalunmatched
  • Cell Culturesunmatched
  • Chemistryunmatched
  • Communication Skillsunmatched
  • Computational Engineeringunmatched
  • Cross-Functionalunmatched
  • Data Setsunmatched
  • Detail Orientedunmatched
  • Drug Discoveryunmatched
  • Drug-Screening Assaysunmatched
  • High Throughputunmatched
  • High-Throughput Screening (HTS)unmatched
  • Identify Issuesunmatched
  • Instrumentationunmatched
  • Laboratory Equipmentunmatched
  • Laboratory Techniquesunmatched
  • MATLABunmatched
  • Machine Learningunmatched
  • Microscopyunmatched
  • Microsoft Product Familyunmatched
  • Operations Processesunmatched
  • Organizational Skillsunmatched
  • Prismunmatched
  • Problem Solving Skillsunmatched
  • Process Improvementunmatched
  • Programming Languagesunmatched
  • Python Programming/Scripting Languageunmatched
  • Quantitative Analysisunmatched
  • R Programming Languageunmatched
  • Regulatory Requirementsunmatched
  • Software Engineeringunmatched
  • Standard Operating Procedures (SOP)unmatched
  • Statistical Analysis System (SAS)unmatched
  • Statistics Softwareunmatched
  • Team Playerunmatched
  • Time Managementunmatched
  • Training Data Setsunmatched

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