Onsite in San Diego, CA. No relocations.
Max Client Bill Rate: ***
6 month contract, with extensions possible.
Position Summary:
*** is searching for an outstanding Scientist II to join the Gene Medicines team in San Diego, CA. This position offers an exciting opportunity to work with new non-viral nucleic acid delivery tools for in vivo genome editing and gene therapy applications. This person will be engaged in the analysis of Client lipid nanoparticle-based pharmaceuticals.
Responsibilities may include but are not limited to:
Work at the direction of Analytical scientists to analyze lipid nanoparticles (LNPs) encapsulating nucleic acids and LNP components using HPLC and Biolayer Interferometry (BLI)
Develop methods to characterize LNPs and LNP components
Establish relationships between physiochemical characteristics of experimental nanoparticle formulations and their efficacy and safety
Maintain detailed records of analytical data
Interface directly with other functional teams
Share responsibility for basic lab management activities (supply ordering, instrument calibration, maintaining schedules)
Requirements, Knowledge, Skills, and Abilities:
Master's or Bachelor's degree with 5+ years experience in pharmaceutical sciences, bioengineering, chemical engineering, chemistry, or related scientific discipline (an equivalent combination of education and experience may be considered).
Experience developing methods in gradient-elution HPLC modalities such as RP, IPRP, or AEX is required
Experience with BLI or Surface Plasmon Resonance (SPR) is highly desirable
Experience with LCMS is desirable
Excellent attention to detail and ability to produce consistent results and effectively communicate them to the team
Ability to be a team player, multitask and work on multiple projects at once, and excel in a collaborative work environment.
Proficiency at MS Excel is required; prior experience with advanced analytical software (Prism, JMP) is desirable
Excellent oral and written communication skills