Scientist

Payrate: $35.00 - $37.00/hr
 
Summary:
We are seeking a motivated and collaborative scientist to join an R&D imaging and image analysis team supporting research programs across multiple therapeutic and functional areas. Our group operates a high-content imaging core and partners with scientists throughout R&D to develop and execute imaging-based assays and enable quantitative cellular research.
 
Preferred Qualifications:

• BS or MS or Ph.D. in cell biology, immunology, bioengineering, biochemistry, biomedical sciences, or a related discipline, with relevant laboratory experience.
• Strong hands-on experience with mammalian cell culture and cell-based assays.
• Experience with fluorescence microscopy and quantitative image analysis.
• Experience with immunofluorescence staining, live-cell imaging, or other microscopy sample-preparation techniques.
• Experience with primary cells, immune cells, co-culture assays, or cell-cell interaction assays is a plus.
• Experience with high-content imaging platforms such as the Opera Phenix is a plus but is not required.
• Experience with automated laboratory workflows, robotic plate handling, or screening environments is beneficial but not required.
• Familiarity with Fiji/ImageJ, Imaris, CellProfiler, Harmony, or related image analysis tools is desirable.
• Programming experience in Python, R, MATLAB, or similar environments is a plus but is not required.

 
Top 3 Must Have Skill Sets:

• Strong mammalian cell culture and experimental skills:

• Hands-on experience culturing mammalian cells and performing cell-based experiments.
• The candidate should demonstrate excellent sterile technique, attention to experimental quality and reproducibility, and the ability to troubleshoot cell-based assays.
• Experience working with primary cells, immune cells, or co-culture systems is desirable but not required.

• Cell-based assay development and sample preparation

• Experience developing, optimizing, or executing cellular assays, including preparation of samples for microscopy or other quantitative readouts.
• The ideal candidate understands how experimental variables—including cell density, timing, treatments, staining, controls, and sample handling—affect assay performance and data quality.

 

• Microscopy and quantitative image analysis experience

• Hands-on experience with fluorescence microscopy and at least one image analysis platform or approach, such as Fiji/ImageJ, Imaris, CellProfiler, commercial imaging software, or custom computational workflows.
• Experience with automated or high-content imaging is beneficial but not required. More important is an interest in quantitative imaging and a willingness to learn new imaging and analysis technologies.

 
Day to Day Responsibilities:

• Maintain mammalian cell cultures and prepare cells and samples for imaging experiments.
• Develop, optimize, and execute image-based cellular assays, including co-culture and cell-cell interaction assays
• Perform fluorescence microscopy and automated imaging experiments.
• Support imaging studies conducted in collaboration with scientists across R&D, from experimental design and sample preparation through image acquisition and analysis.
• Develop and apply quantitative image analysis workflows using tools such as Fiji/ImageJ, Imaris, high-content analysis software, or other computational approaches.
• Analyze, interpret, document, and communicate experimental results.
• Contribute to research focused on immune synapses, cell-cell contacts, and other imaging-based approaches relevant to T-cell engager research.
• Assist with operation and routine maintenance of automated high-content imaging instrumentation, including Opera Phenix systems and associated automation.
• Troubleshoot imaging, assay, and sample-preparation issues and work with team members to identify practical solutions.
• Help maintain robust and reproducible imaging workflows, protocols, and documentation.
• Support and, with experience, help train scientists using imaging instrumentation and analysis tools.
• Work collaboratively with imaging scientists, biologists, and project teams across different areas of R&D.
• Learn and adopt new microscopy, automation, assay-development, and image-analysis technologies as needed.

 
Pay Transparency: The typical base pay for this role across the U.S. is: $35.00 - $37.00/hr Non-exempt positions are eligible for overtime at a rate of 1.5 times the base hourly rate for all hours worked in excess of 40 in a work week, or as required by state or local law. Final offer amounts, within the base pay set forth above, are determined by factors including your relevant skills, education and experience. Full-time employees are eligible to select from different benefits packages. Packages may include medical, dental, and vision benefits, health savings accounts with qualified medical plan enrollment, 10 paid days off, 3 days paid bereavement leave, 401(k) plan participation with employer match, life and disability insurance, commuter benefits, dependent care flexible spending account, accident insurance, critical illness insurance, hospital indemnity insurance, accommodations and reimbursement for work travel, and discretionary performance or recognition bonus. Sick leave and mobile phone reimbursement provided based on state or local law. 

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