Senior Clinical Trial Associate

Join Immatics and shape the future of cancer immunotherapy; one patient at a time!   

Immatics is committed to making a meaningful impact on the lives of patients with cancer. We are the global leader in precision targeting of PRAME, a target expressed in more than 50 cancers. Our cutting-edge science and robust clinical pipeline form the broadest PRAME franchise with the most PRAME indications and modalities, spanning TCR T-cell therapies and TCR bispecifics.  

Why Join Us?  

• Innovative Environment: Help to pioneer advancements in cancer immunotherapy.  

• Collaborative Culture: Be part of a diverse team dedicated to your professional growth.  

• Global Impact: Contribute to therapies that make a lasting impact on patients globally.  

Role Overview  

We are seeking a highly organized and proactive Senior Clinical Trial Associate (CTA) to join our Clinical Operations team. In this pivotal role, you will help drive the successful execution of clinical trials by providing critical operational and administrative support, ensuring studies are conducted efficiently, compliantly, and with the highest standards of quality. 

Reports to: Associate Director, Team Lead Site Operations  

Location: US,Fully Remote  

Salary Range: $95,000 to $120,000  

Basic Qualifications:  

• Bachelor’s degree in life sciences, nursing, or a related field 

• 4+ years’ working experience in the clinical research area in the Pharmaceutical or Biotech industry with ICH-GCP knowledge, or equivalent 

Preferred Qualifications:   

• Strong problem-solving skills with the ability to analyze issues, identify root causes, and implement effective solutions. 

• Self-motivated and able to work independently in a fast-paced environment. 

• Strong understanding of clinical trial processes and interconnected operational workflows. 

• Continuous improvement mindset with a passion for enhancing processes and team effectiveness. 

• Demonstrated ability to drive innovation and share expertise across teams.  

In this role you will:  

• Support clinical trial start-up, activation, maintenance, and closeout activities, ensuring timely collection and management of essential study documents. 

• Maintain and perform quality reviews of trial information within CTMS, eTMF, and other clinical systems. 

• Partner with internal teams, CROs, vendors, and investigative sites to drive study execution and resolve operational issues. 

• Support inspection and audit readiness through accurate, complete, and compliant trial documentation. 

• Coordinate trial-related meetings, documentation reviews, approvals, and key administrative activities. 

• Manage purchase orders, invoices, investigator payments, and study-related financial tracking. 

• Prepare, review, and quality-check study documents, reports, trackers, and investigator site files. 

• Support TMF and ISF maintenance, reconciliation, and quality oversight to ensure ongoing compliance. 

• Coordinate training assignments, system access, and compliance tracking for study teams. 

• Monitor site issues, action items, and data query resolution to support study milestones. 

• Support tracking and follow-up of outstanding EDC queries and facilitate timely resolution by appropriate study team members and/or sites. 

• Facilitate site communications, including study updates, newsletters, and distribution of trial materials. 

• Contribute to risk identification, issue escalation, process improvements, and inspection readiness efforts. 

• Support the development of SOPs, work instructions, guidance documents, and training materials. 

• May assist with remote and on-site monitoring activities, as appropriate. 

Travel Requirements: 

• Optional travelling for business reasons  

Qualified candidates will participate in a structured interview process, which includes: 

• An initial recruiter phone screen (conducted via video) 

• Interviews with the hiring leader and other key stakeholders (via video) 

• A final-stage interview 

What do we offer?   

At Immatics, we believe in investing in our team’s health, safety and well-being. Here’s what you can expect if you join Immatics  

Comprehensive Benefits:   

• Competitive rates for Health, Dental, and Vision Insurance  

• 4 weeks of vacation, granted up front each year and prorated for first and last year of employment.  

• 12 company paid holidays  

• 7 days of sick time  

• 100% employer-paid life insurance up to at 1x annual salary, up to one hundred thousand dollars   

• 100% employer-paid short- and long-Term disability coverage   

• 401(k) with immediate eligibility and company match. The company will match 100% of your contributions up to 3% of your base salary for the first two years of employment, 4% for years 2-3 of employment, and up to 5% of your salary from the fourth year onward of continued employment.  

• Partially paid parental leave for eligible employees.  

• Additional voluntary employee-paid benefits and services, including accident, hospital indemnity, and critical illness insurance, as well as identity theft protection and pet insurance.   

Equal Employment Opportunity 

We are an equal opportunity employer and are committed to building a diverse and inclusive workplace.  We consider all qualified applicants for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity or expression, national origin, ancestry, age, marital status, disability, genetic information, veteran status, or any other status protected by applicable law.   

Reasonable Accommodations 

We are committed to providing reasonable accommodations to individuals with disabilities and to applicants with sincerely held religious beliefs, practices, or observances.  If you require assistance or accommodation during the application or interview process, please contact us at 

RecruitingUS@immatics.com

Work Authorization 

Applicants must be authorized to work in the United States without the need for current or future sponsorship. 

Pre-Employment Requirements 

Employment is contingent upon successful completion of a background check, reference checks and pre-employment drug screening, where permitted by applicable law.  For certain roles, additional screenings such as a credit check or motor vehicle record review may be required, where job-related and consistent with business necessity.   

Notice to Staffing Agencies and Third-Party Recruiters 

Immatics US partners with a select group of approved staffing agencies. Candidate submissions are accepted only from agencies that have a current written agreement with Immatics US and signed and formally engaged by our Talent Acquisition team for an active search. Unsolicited resumes or candidate information, including submissions made directly to hiring managers, will not be considered and are not eligible for placement fees.