Senior Research Associate – Next-Generation Sequencing (NGS) needs 3–5 years of bench experience falls dire
- End-to-End Library Prep:
Lead RNA-seq, bulk, amplicon, and highly specialized single-cell (scRNA-seq) and single-nucleus (snRNA-seq) sequencing workflows.
- Target Identification: Design and execute molecular and cell biology experiments to identify and validate novel drug targets.
- Assay Optimization:
Support assay design, optimization, validation, and complex data quality control (QC).
- Troubleshooting: Diagnose and resolve complex technical data anomalies to keep drug discovery projects moving forward.
- Collaborative Reporting:
Translate complex experimental results into clear oral presentations and written documentation.
- Education & Experience:
B.S. and/or M.S. in biological or biochemical sciences with 3–5 years of hands-on laboratory research experience.
- Molecular Biology Mastery:
Proven expertise in nucleic acid extraction, purification, quantification, qPCR, and NGS library prep/QC.
- Advanced Sequencing Background:
Deep understanding of NGS technologies and data QC (preferably Illumina), with direct experience in bulk RNA-seq and amplicon-seq.
- Single-Cell Expertise:
Direct experience with scRNA-seq and snRNA-seq library preparation is required. You must be familiar with multiple platforms (e.g., 10X Genomics Chromium, Illumina PIP-seq, ScaleBio, or Parse Biosciences).
- Operational Excellence:
Experience documenting experiments in electronic notebook software, alongside exceptional organizational and time-management skills.
Preferred Extras (A Plus, But Not Required)
- Familiarity with CRISPR-based gene editing and high-throughput screening.
- Experience operating lab automation equipment (Mantis, Integra systems, liquid handlers, SPTLabtech Firefly, Tecan, etc.).